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Items: 1 to 20 of 48

1.

Individual and Familial Susceptibility to MPTP in a Common Marmoset Model for Parkinson's Disease.

Franke SK, van Kesteren RE, Hofman S, Wubben JA, Smit AB, Philippens IH.

Neurodegener Dis. 2016 Mar 22. [Epub ahead of print]

PMID:
26999593
2.

Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels.

Schreiber J, Végh MJ, Dawitz J, Kroon T, Loos M, Labonté D, Li KW, Van Nierop P, Van Diepen MT, De Zeeuw CI, Kneussel M, Meredith RM, Smit AB, Van Kesteren RE.

J Cell Biol. 2015 Nov 9;211(3):569-86. doi: 10.1083/jcb.201506048. Epub 2015 Nov 2.

3.

Progression and recovery of Parkinsonism in a chronic progressive MPTP-induction model in the marmoset without persistent molecular and cellular damage.

Franke SK, van Kesteren RE, Wubben JA, Hofman S, Paliukhovich I, van der Schors RC, van Nierop P, Smit AB, Philippens IH.

Neuroscience. 2016 Jan 15;312:247-59. doi: 10.1016/j.neuroscience.2015.09.065. Epub 2015 Oct 9.

PMID:
26431624
4.

Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson's Disease.

Dijkstra AA, Ingrassia A, de Menezes RX, van Kesteren RE, Rozemuller AJ, Heutink P, van de Berg WD.

PLoS One. 2015 Jun 18;10(6):e0128651. doi: 10.1371/journal.pone.0128651. eCollection 2015.

5.

Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2.

Wiemhoefer A, Stargardt A, van der Linden WA, Renner MC, van Kesteren RE, Stap J, Raspe MA, Tomkinson B, Kessels HW, Ovaa H, Overkleeft HS, Florea B, Reits EA.

Mol Cell Proteomics. 2015 Aug;14(8):2177-93. doi: 10.1074/mcp.M114.043331. Epub 2015 Jun 3.

PMID:
26041847
6.

Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo.

van der Kallen LR, Eggers R, Ehlert EM, Verhaagen J, Smit AB, van Kesteren RE.

PLoS One. 2015 May 20;10(5):e0127163. doi: 10.1371/journal.pone.0127163. eCollection 2015.

7.

Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.

Végh MJ, Rausell A, Loos M, Heldring CM, Jurkowski W, van Nierop P, Paliukhovich I, Li KW, del Sol A, Smit AB, Spijker S, van Kesteren RE.

Mol Cell Proteomics. 2014 Nov;13(11):2975-85. doi: 10.1074/mcp.M113.032086. Epub 2014 Jul 20.

8.

Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease.

Végh MJ, Heldring CM, Kamphuis W, Hijazi S, Timmerman AJ, Li KW, van Nierop P, Mansvelder HD, Hol EM, Smit AB, van Kesteren RE.

Acta Neuropathol Commun. 2014 Jun 29;2:76. doi: 10.1186/s40478-014-0076-z.

9.

TRIM3 regulates the motility of the kinesin motor protein KIF21B.

Labonté D, Thies E, Pechmann Y, Groffen AJ, Verhage M, Smit AB, van Kesteren RE, Kneussel M.

PLoS One. 2013 Sep 24;8(9):e75603. doi: 10.1371/journal.pone.0075603. eCollection 2013.

10.

FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain.

Rizzi TS, van der Sluis S, Derom C, Thiery E, van Kesteren RE, Jacobs N, Van Gestel S, Vlietinck R, Verhage M, Heutink P, Posthuma D.

PLoS One. 2013 Jun 27;8(6):e68000. doi: 10.1371/journal.pone.0068000. Print 2013.

11.

A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons.

Roet KC, Franssen EH, de Bree FM, Essing AH, Zijlstra SJ, Fagoe ND, Eggink HM, Eggers R, Smit AB, van Kesteren RE, Verhaagen J.

J Neurosci. 2013 Jul 3;33(27):11116-35. doi: 10.1523/JNEUROSCI.1002-13.2013.

12.

Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling.

Korecka JA, van Kesteren RE, Blaas E, Spitzer SO, Kamstra JH, Smit AB, Swaab DF, Verhaagen J, Bossers K.

PLoS One. 2013 May 28;8(5):e63862. doi: 10.1371/journal.pone.0063862. Print 2013.

13.

Molecular target discovery for neural repair in the functional genomics era.

Verhaagen J, Van Kesteren RE, Bossers KA, Macgillavry HD, Mason MR, Smit AB.

Handb Clin Neurol. 2012;109:595-616. doi: 10.1016/B978-0-444-52137-8.00037-1. Review.

PMID:
23098739
14.

Synaptic proteome changes in a DNA repair deficient ercc1 mouse model of accelerated aging.

Végh MJ, de Waard MC, van der Pluijm I, Ridwan Y, Sassen MJ, van Nierop P, van der Schors RC, Li KW, Hoeijmakers JH, Smit AB, van Kesteren RE.

J Proteome Res. 2012 Mar 2;11(3):1855-67. doi: 10.1021/pr201203m. Epub 2012 Feb 13.

PMID:
22289077
15.

High content screening in neurodegenerative diseases.

Jain S, van Kesteren RE, Heutink P.

J Vis Exp. 2012 Jan 6;(59):e3452. doi: 10.3791/3452.

16.

A gene network perspective on axonal regeneration.

van Kesteren RE, Mason MR, Macgillavry HD, Smit AB, Verhaagen J.

Front Mol Neurosci. 2011 Nov 22;4:46. doi: 10.3389/fnmol.2011.00046. eCollection 2011.

17.

Identification of context-specific gene regulatory networks with GEMULA--gene expression modeling using LAsso.

Geeven G, van Kesteren RE, Smit AB, de Gunst MC.

Bioinformatics. 2012 Jan 15;28(2):214-21. doi: 10.1093/bioinformatics/btr641. Epub 2011 Nov 21.

18.

Caltubin, a novel molluscan tubulin-interacting protein, promotes axonal growth and attenuates axonal degeneration of rodent neurons.

Nejatbakhsh N, Guo CH, Lu TZ, Pei L, Smit AB, Sun HS, van Kesteren RE, Feng ZP.

J Neurosci. 2011 Oct 26;31(43):15231-44. doi: 10.1523/JNEUROSCI.2516-11.2011.

19.

LLM3D: a log-linear modeling-based method to predict functional gene regulatory interactions from genome-wide expression data.

Geeven G, Macgillavry HD, Eggers R, Sassen MM, Verhaagen J, Smit AB, de Gunst MC, van Kesteren RE.

Nucleic Acids Res. 2011 Jul;39(13):5313-27. doi: 10.1093/nar/gkr139. Epub 2011 Mar 21.

20.

Defective glial maturation in vanishing white matter disease.

Bugiani M, Boor I, van Kollenburg B, Postma N, Polder E, van Berkel C, van Kesteren RE, Windrem MS, Hol EM, Scheper GC, Goldman SA, van der Knaap MS.

J Neuropathol Exp Neurol. 2011 Jan;70(1):69-82. doi: 10.1097/NEN.0b013e318203ae74.

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