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Results: 1 to 20 of 23


In vitro model suggests oxidative stress involved in keratoconus disease.

Karamichos D, Hutcheon AE, Rich CB, Trinkaus-Randall V, Asara JM, Zieske JD.

Sci Rep. 2014 Apr 9;4:4608. doi: 10.1038/srep04608.


Wounding the cornea to learn how it heals.

Stepp MA, Zieske JD, Trinkaus-Randall V, Kyne BM, Pal-Ghosh S, Tadvalkar G, Pajoohesh-Ganji A.

Exp Eye Res. 2014 Apr;121:178-93. doi: 10.1016/j.exer.2014.02.007. Epub 2014 Mar 4. Review.


TGF-β3 stimulates stromal matrix assembly by human corneal keratocyte-like cells.

Karamichos D, Rich CB, Zareian R, Hutcheon AE, Ruberti JW, Trinkaus-Randall V, Zieske JD.

Invest Ophthalmol Vis Sci. 2013 Oct 9;54(10):6612-9. doi: 10.1167/iovs.13-12861.


Communication between corneal epithelial cells and trigeminal neurons is facilitated by purinergic (P2) and glutamatergic receptors.

Oswald DJ, Lee A, Trinidad M, Chi C, Ren R, Rich CB, Trinkaus-Randall V.

PLoS One. 2012;7(9):e44574. doi: 10.1371/journal.pone.0044574. Epub 2012 Sep 7.


Disorganized collagen scaffold interferes with fibroblast mediated deposition of organized extracellular matrix in vitro.

Saeidi N, Guo X, Hutcheon AE, Sander EA, Bale SS, Melotti SA, Zieske JD, Trinkaus-Randall V, Ruberti JW.

Biotechnol Bioeng. 2012 Oct;109(10):2683-98. doi: 10.1002/bit.24533. Epub 2012 May 4.


The P2X(7) receptor regulates proteoglycan expression in the corneal stroma.

Mankus C, Chi C, Rich C, Ren R, Trinkaus-Randall V.

Mol Vis. 2012;18:128-38. Epub 2012 Jan 18.


Corneal epithelium expresses a variant of P2X(7) receptor in health and disease.

Mankus C, Rich C, Minns M, Trinkaus-Randall V.

PLoS One. 2011;6(12):e28541. doi: 10.1371/journal.pone.0028541. Epub 2011 Dec 6.


Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis.

Ward JE, Ren R, Toraldo G, Soohoo P, Guan J, O'Hara C, Jasuja R, Trinkaus-Randall V, Liao R, Connors LH, Seldin DC.

Blood. 2011 Dec 15;118(25):6610-7. doi: 10.1182/blood-2011-04-351643. Epub 2011 Oct 12.


Distinct activation of epidermal growth factor receptor by UTP contributes to epithelial cell wound repair.

Boucher I, Kehasse A, Marcincin M, Rich C, Rahimi N, Trinkaus-Randall V.

Am J Pathol. 2011 Mar;178(3):1092-105. doi: 10.1016/j.ajpath.2010.11.060.


Self-assembled matrix by umbilical cord stem cells.

Karamichos D, Rich CB, Hutcheon AE, Ren R, Saitta B, Trinkaus-Randall V, Zieske JD.

J Funct Biomater. 2011 Sep 1;2(3):213-29. doi: 10.3390/jfb2030213.


Role of glycosaminoglycan sulfation in the formation of immunoglobulin light chain amyloid oligomers and fibrils.

Ren R, Hong Z, Gong H, Laporte K, Skinner M, Seldin DC, Costello CE, Connors LH, Trinkaus-Randall V.

J Biol Chem. 2010 Nov 26;285(48):37672-82. doi: 10.1074/jbc.M110.149575. Epub 2010 Sep 24.


The P2Y2 receptor mediates the epithelial injury response and cell migration.

Boucher I, Rich C, Lee A, Marcincin M, Trinkaus-Randall V.

Am J Physiol Cell Physiol. 2010 Aug;299(2):C411-21. doi: 10.1152/ajpcell.00100.2009. Epub 2010 Apr 28.


RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1.

Wang X, Belguise K, O'Neill CF, Sánchez-Morgan N, Romagnoli M, Eddy SF, Mineva ND, Yu Z, Min C, Trinkaus-Randall V, Chalbos D, Sonenshein GE.

Mol Cell Biol. 2009 Jul;29(14):3832-44. doi: 10.1128/MCB.00032-09. Epub 2009 May 11.


Human primary corneal fibroblasts synthesize and deposit proteoglycans in long-term 3-D cultures.

Ren R, Hutcheon AE, Guo XQ, Saeidi N, Melotti SA, Ruberti JW, Zieske JD, Trinkaus-Randall V.

Dev Dyn. 2008 Oct;237(10):2705-15. doi: 10.1002/dvdy.21606.


Regulation by P2X7: epithelial migration and stromal organization in the cornea.

Mayo C, Ren R, Rich C, Stepp MA, Trinkaus-Randall V.

Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4384-91. doi: 10.1167/iovs.08-1688. Epub 2008 May 23.


Tri-nucleotide receptors play a critical role in epithelial cell wound repair.

Weinger I, Klepeis VE, Trinkaus-Randall V.

Purinergic Signal. 2005 Sep;1(3):281-92. doi: 10.1007/s11302-005-8132-6. Epub 2005 Jul 29.


Injury and nucleotides induce phosphorylation of epidermal growth factor receptor: MMP and HB-EGF dependent pathway.

Boucher I, Yang L, Mayo C, Klepeis V, Trinkaus-Randall V.

Exp Eye Res. 2007 Jul;85(1):130-41. Epub 2007 Mar 31.


Role of endocytic inhibitory drugs on internalization of amyloidogenic light chains by cardiac fibroblasts.

Monis GF, Schultz C, Ren R, Eberhard J, Costello C, Connors L, Skinner M, Trinkaus-Randall V.

Am J Pathol. 2006 Dec;169(6):1939-52.


Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways.

Kaczmarek E, Erb L, Koziak K, Jarzyna R, Wink MR, Guckelberger O, Blusztajn JK, Trinkaus-Randall V, Weisman GA, Robson SC.

Thromb Haemost. 2005 Apr;93(4):735-42.


Cellular response of cardiac fibroblasts to amyloidogenic light chains.

Trinkaus-Randall V, Walsh MT, Steeves S, Monis G, Connors LH, Skinner M.

Am J Pathol. 2005 Jan;166(1):197-208.

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