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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 19
2002 2
2003 5
2004 3
2005 3
2006 6
2007 4
2008 5
2009 1
2010 5
2011 3
2012 2
2013 3
2014 8
2015 8
2016 10
2017 3
2024 0

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80 results

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Page 1
The rasH2 transgenic mouse: nature of the model and mechanistic studies on tumorigenesis.
Tamaoki N. Tamaoki N. Toxicol Pathol. 2001;29 Suppl:81-9. doi: 10.1080/019262301753178492. Toxicol Pathol. 2001. PMID: 11695564 Review.
The rasH2 mouse is a hemizygous transgenic mouse carrying the c-Ha-ras oncogene and that gene's promotor/enhancer within the genetic background of a BALB/cByJ x C57BL/6J F1 mouse. ...Hemizygotes are selected by polymerase chain reaction (PCR) analysis …
The rasH2 mouse is a hemizygous transgenic mouse carrying the c-Ha-ras oncogene and that gene's promotor/enhancer withi …
Mouse models in oncoimmunology.
Zitvogel L, Pitt JM, Daillère R, Smyth MJ, Kroemer G. Zitvogel L, et al. Nat Rev Cancer. 2016 Dec;16(12):759-773. doi: 10.1038/nrc.2016.91. Epub 2016 Sep 30. Nat Rev Cancer. 2016. PMID: 27687979 Review.
Specific aspects of pharmacological development, as well as attempts to personalize cancer treatments using patient-derived xenografts, require the development of mouse models in which murine genes and cells are replaced with their human equivalents. Such 'humanized …
Specific aspects of pharmacological development, as well as attempts to personalize cancer treatments using patient-derived xenografts, requ …
Promising future for the transgenic rat in transplantation research.
Doorschodt BM, Teubner A, Kobayashi E, Tolba RH. Doorschodt BM, et al. Transplant Rev (Orlando). 2014 Oct;28(4):155-62. doi: 10.1016/j.trre.2014.05.002. Epub 2014 May 27. Transplant Rev (Orlando). 2014. PMID: 24975516 Review.
The rat is the most widely used animal species in surgical research and offers distinct advantages over the mouse in transplantation models due to its size and close genetic similarity to humans. Sequencing of the rat genome and successful application of t …
The rat is the most widely used animal species in surgical research and offers distinct advantages over the mouse in transplan …
The Tg.AC (v-Ha-ras) transgenic mouse: nature of the model.
Tennant RW, Stasiewicz S, Eastin WC, Mennear JH, Spalding JW. Tennant RW, et al. Toxicol Pathol. 2001;29 Suppl:51-9. doi: 10.1080/019262301753178474. Toxicol Pathol. 2001. PMID: 11695562 Review.
The Tg.AC (v-Ha-ras) transgenic mouse model provides a reporter phenotype of skin papillomas in response to either genotoxic or nongenotoxic carcinogens. In common with the conventional bioassay, the Tg.AC model responds to known human carcinogens and …
The Tg.AC (v-Ha-ras) transgenic mouse model provides a reporter phenotype of skin papillomas in response to either geno …
How genetically engineered mouse tumor models provide insights into human cancers.
Politi K, Pao W. Politi K, et al. J Clin Oncol. 2011 Jun 1;29(16):2273-81. doi: 10.1200/JCO.2010.30.8304. Epub 2011 Jan 24. J Clin Oncol. 2011. PMID: 21263096 Free PMC article. Review.
Genetically engineered mouse models (GEMMs) of human cancer were first created nearly 30 years ago. These early transgenic models demonstrated that mouse cells could be transformed in vivo by expression of an oncogene. ...
Genetically engineered mouse models (GEMMs) of human cancer were first created nearly 30 years ago. These early transgenic …
Prolonged pain research in mice: trends in reference to the 3Rs.
Balcombe J, Ferdowsian H, Briese L. Balcombe J, et al. J Appl Anim Welf Sci. 2013;16(1):77-95. doi: 10.1080/10888705.2013.741004. J Appl Anim Welf Sci. 2013. PMID: 23282295 Review.
There has also been a significant rise in the number of prolonged mouse pain studies as a proportion of all mouse studies and of all mouse pain studies. The use of transgenic mice has also risen significantly in prolonged pain research, though n …
There has also been a significant rise in the number of prolonged mouse pain studies as a proportion of all mouse studies and …
Piscine islet xenotransplantation.
Wright JR Jr, Pohajdak B, Xu BY, Leventhal JR. Wright JR Jr, et al. ILAR J. 2004;45(3):314-23. doi: 10.1093/ilar.45.3.314. ILAR J. 2004. PMID: 15229378 Review.
When transplanted into streptozotocin-diabetic nude or severe combined immunodeficient mice, BBs provide long-term normoglycemia and mammalian-like glucose tolerance profiles. ...Future improvements on these transgenic fish may allow tilapia to play an important rol …
When transplanted into streptozotocin-diabetic nude or severe combined immunodeficient mice, BBs provide long-term normoglycemia and …
Spontaneous and genetically engineered animal models; use in preclinical cancer drug development.
Hansen K, Khanna C. Hansen K, et al. Eur J Cancer. 2004 Apr;40(6):858-80. doi: 10.1016/j.ejca.2003.11.031. Eur J Cancer. 2004. PMID: 15120042 Review.
The preclinical development of anticancer drugs has been based primarily on the transplantation of murine or human cancers into mice. Alternatives to these transplantation models are animals that naturally develop cancers with features relevant to the human d …
The preclinical development of anticancer drugs has been based primarily on the transplantation of murine or human cancers into mice. …
Use of genetically modified mouse models for evaluation of carcinogenic risk: considerations for the laboratory animal scientist.
Recio L, Everitt J. Recio L, et al. Comp Med. 2001 Oct;51(5):399-405. Comp Med. 2001. PMID: 11924798 Review.
There has been increasing interest in the use of selected genetically modified (GM) mouse models for the testing of chemicals to determine their carcinogenic potential. ...They have been proposed as alternatives to the traditional 2-year mouse oncogeni …
There has been increasing interest in the use of selected genetically modified (GM) mouse models for the testing of chemicals …
DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models.
van Steeg H, de Vries A, van Oostrom CTh, van Benthem J, Beems RB, van Kreijl CF. van Steeg H, et al. Toxicol Pathol. 2001;29 Suppl:109-16. doi: 10.1080/019262301753178519. Toxicol Pathol. 2001. PMID: 11695546 Review.
Based on these phenotypic characteristics, the Xpa mice were considered to be an attractive candidate mouse model for use in identifying human carcinogens. ...It appeared that the Xpa/p53+/- double knockout mouse model is favorable over both the …
Based on these phenotypic characteristics, the Xpa mice were considered to be an attractive candidate mouse model for u …
80 results