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Results: 1 to 20 of 152

1.

Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model.

Robbins GR, Roberts RA, Guo H, Reuter K, Shen T, Sempowski GD, McKinnon KP, Su L, DeSimone JM, Ting JP.

Nanomedicine. 2015 Jan 14. pii: S1549-9634(15)00004-0. doi: 10.1016/j.nano.2014.11.010. [Epub ahead of print]

PMID:
25596079
[PubMed - as supplied by publisher]
2.

Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization.

Fromen CA, Robbins GR, Shen TW, Kai MP, Ting JP, DeSimone JM.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):488-93. doi: 10.1073/pnas.1422923112. Epub 2014 Dec 29.

PMID:
25548169
[PubMed - in process]
3.

G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3.

Giguère PM, Gall BJ, Ezekwe EA Jr, Laroche G, Buckley BK, Kebaier C, Wilson JE, Ting JP, Siderovski DP, Duncan JA.

J Biol Chem. 2014 Nov 28;289(48):33245-57. doi: 10.1074/jbc.M114.578393. Epub 2014 Sep 30.

PMID:
25271165
[PubMed - in process]
4.

MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma.

Fang L, Gong J, Wang Y, Liu R, Li Z, Wang Z, Zhang Y, Zhang C, Song C, Yang A, Ting JP, Jin B, Chen L.

J Exp Clin Cancer Res. 2014 Sep 18;33(1):76. [Epub ahead of print]

PMID:
25228093
[PubMed - as supplied by publisher]
Free PMC Article
5.

The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation.

Rodgers MA, Bowman JW, Fujita H, Orazio N, Shi M, Liang Q, Amatya R, Kelly TJ, Iwai K, Ting J, Jung JU.

J Exp Med. 2014 Jun 30;211(7):1333-47. doi: 10.1084/jem.20132486. Epub 2014 Jun 23.

PMID:
24958845
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes.

Guo H, Gao J, Taxman DJ, Ting JP, Su L.

J Biol Chem. 2014 Aug 1;289(31):21716-26. doi: 10.1074/jbc.M114.566620. Epub 2014 Jun 17.

PMID:
24939850
[PubMed - indexed for MEDLINE]
7.

Inflammasomes and metabolic disorders: old genes in modern diseases.

Robbins GR, Wen H, Ting JP.

Mol Cell. 2014 Apr 24;54(2):297-308. doi: 10.1016/j.molcel.2014.03.029. Review.

PMID:
24766894
[PubMed - indexed for MEDLINE]
8.

Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.

Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE.

J Immunol. 2014 Apr 15;192(8):3958-68. doi: 10.4049/jimmunol.1301533. Epub 2014 Mar 14.

PMID:
24634494
[PubMed - indexed for MEDLINE]
9.

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.

Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, Ting JP.

Immunity. 2014 Mar 20;40(3):329-41. doi: 10.1016/j.immuni.2014.01.010. Epub 2014 Feb 20. Review.

PMID:
24560620
[PubMed - indexed for MEDLINE]
10.

The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.

Eitas TK, Chou WC, Wen H, Gris D, Robbins GR, Brickey J, Oyama Y, Ting JP.

J Biol Chem. 2014 Feb 14;289(7):4173-9. doi: 10.1074/jbc.M113.533034. Epub 2013 Dec 23.

PMID:
24366868
[PubMed - indexed for MEDLINE]
11.

Mechanisms of NOD-like receptor-associated inflammasome activation.

Wen H, Miao EA, Ting JP.

Immunity. 2013 Sep 19;39(3):432-41. doi: 10.1016/j.immuni.2013.08.037. Review.

PMID:
24054327
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.

Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C.

EMBO Rep. 2013 Oct;14(10):900-6. doi: 10.1038/embor.2013.132. Epub 2013 Sep 6.

PMID:
24008845
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Nanoparticle clearance is governed by Th1/Th2 immunity and strain background.

Jones SW, Roberts RA, Robbins GR, Perry JL, Kai MP, Chen K, Bo T, Napier ME, Ting JP, Desimone JM, Bear JE.

J Clin Invest. 2013 Jul 1;123(7):3061-73. doi: 10.1172/JCI66895. Epub 2013 Jun 17.

PMID:
23778144
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Agitation by suffocation: how hypoxia activates innate immunity via the Warburg effect.

Wen H, Ting JP.

Cell Metab. 2013 Jun 4;17(6):814-5. doi: 10.1016/j.cmet.2013.05.016.

PMID:
23747241
[PubMed - indexed for MEDLINE]
Free Article
15.

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.

Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, Sher A.

J Immunol. 2013 Jun 1;190(11):5722-30. doi: 10.4049/jimmunol.1203343. Epub 2013 Apr 29.

PMID:
23630357
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles.

Roberts RA, Shen T, Allen IC, Hasan W, DeSimone JM, Ting JP.

PLoS One. 2013 Apr 12;8(4):e62115. doi: 10.1371/journal.pone.0062115. Print 2013.

PMID:
23593509
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.

Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM.

PLoS Pathog. 2013;9(4):e1003256. doi: 10.1371/journal.ppat.1003256. Epub 2013 Apr 11.

PMID:
23592984
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis.

Allen IC, McElvania-TeKippe E, Wilson JE, Lich JD, Arthur JC, Sullivan JT, Braunstein M, Ting JP.

PLoS One. 2013;8(4):e60842. doi: 10.1371/journal.pone.0060842. Epub 2013 Apr 5.

PMID:
23577168
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance.

Xie L, Liu C, Wang L, Gunawardena HP, Yu Y, Du R, Taxman DJ, Dai P, Yan Z, Yu J, Holly SP, Parise LV, Wan YY, Ting JP, Chen X.

Cell Rep. 2013 Mar 28;3(3):678-88. doi: 10.1016/j.celrep.2013.01.029. Epub 2013 Feb 21.

PMID:
23434512
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy.

Lei Y, Wen H, Ting JP.

Autophagy. 2013 Mar;9(3):432-3. doi: 10.4161/auto.23026. Epub 2013 Jan 15.

PMID:
23321557
[PubMed - indexed for MEDLINE]
Free PMC Article
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