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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1889 1
1896 1
1925 1
1929 2
1930 1
1932 1
1933 2
1935 1
1938 3
1939 2
1940 1
1943 2
1944 1
1945 5
1946 98
1947 139
1948 137
1949 107
1950 142
1951 161
1952 147
1953 206
1954 279
1955 246
1956 236
1957 263
1958 252
1959 222
1960 278
1961 287
1962 423
1963 640
1964 1119
1965 899
1966 887
1967 1055
1968 1334
1969 1434
1970 1558
1971 1658
1972 1571
1973 1597
1974 1688
1975 1461
1976 1205
1977 1219
1978 1155
1979 1128
1980 1110
1981 1167
1982 1206
1983 1307
1984 1511
1985 1512
1986 1597
1987 1558
1988 1615
1989 1699
1990 1746
1991 1813
1992 1915
1993 1926
1994 2065
1995 2175
1996 2278
1997 2332
1998 2318
1999 2295
2000 2619
2001 2598
2002 2787
2003 2870
2004 3076
2005 3425
2006 3510
2007 3653
2008 3710
2009 3686
2010 3955
2011 4150
2012 4252
2013 4378
2014 4182
2015 4092
2016 3871
2017 3845
2018 3911
2019 3955
2020 4019
2021 3846
2022 3720
2023 3405
2024 1290

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139,511 results

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Page 1
Thiol-based antioxidants.
Deneke SM. Deneke SM. Curr Top Cell Regul. 2000;36:151-80. doi: 10.1016/s0070-2137(01)80007-8. Curr Top Cell Regul. 2000. PMID: 10842751 Review.
Exogenous thiols have been used successfully to increase cell and tissue thiol levels in cell cultures, in animal models, and in humans. ...A wide variety of thiol-related compounds have been used for these purposes. These include thiols such as …
Exogenous thiols have been used successfully to increase cell and tissue thiol levels in cell cultures, in animal models, and …
Thiol redox proteomics: Characterization of thiol-based post-translational modifications.
Li X, Gluth A, Zhang T, Qian WJ. Li X, et al. Proteomics. 2023 Jul;23(13-14):e2200194. doi: 10.1002/pmic.202200194. Epub 2023 May 29. Proteomics. 2023. PMID: 37248656 Free PMC article. Review.
Redox post-translational modifications on cysteine thiols (redox PTMs) have profound effects on protein structure and function, thus enabling regulation of various biological processes. ...A group of well-established approaches involves the initial blocking of free thio
Redox post-translational modifications on cysteine thiols (redox PTMs) have profound effects on protein structure and function, thus …
Fluorescent Probes for Live Cell Thiol Detection.
Wang S, Huang Y, Guan X. Wang S, et al. Molecules. 2021 Jun 11;26(12):3575. doi: 10.3390/molecules26123575. Molecules. 2021. PMID: 34208153 Free PMC article. Review.
Thiols play vital and irreplaceable roles in the biological system. Abnormality of thiol levels has been linked with various diseases and biological disorders. ...
Thiols play vital and irreplaceable roles in the biological system. Abnormality of thiol levels has been linked with various d
Thiol reactive probes and chemosensors.
Peng H, Chen W, Cheng Y, Hakuna L, Strongin R, Wang B. Peng H, et al. Sensors (Basel). 2012 Nov 19;12(11):15907-46. doi: 10.3390/s121115907. Sensors (Basel). 2012. PMID: 23202239 Free PMC article. Review.
Thiols are important molecules in the environment and in biological processes. ...This review focuses on the design of fluorescent and colorimetric probes and sensors for thiol detection. Thiol detection methods include probes and labeling agents based on nuc
Thiols are important molecules in the environment and in biological processes. ...This review focuses on the design of fluorescent an
Thiol-Based Redox Modulation of Soluble Guanylyl Cyclase, the Nitric Oxide Receptor.
Beuve A. Beuve A. Antioxid Redox Signal. 2017 Jan 20;26(3):137-149. doi: 10.1089/ars.2015.6591. Epub 2016 Apr 1. Antioxid Redox Signal. 2017. PMID: 26906466 Free PMC article. Review.
This thiol-based resistance to NO (e.g., increase in peripheral resistance) is observed in hypertension and hyperaldosteronism. ...To understand modulation of sGC activity, it is critical to investigate the roles of specific oxidative thiol modifications that are fo …
This thiol-based resistance to NO (e.g., increase in peripheral resistance) is observed in hypertension and hyperaldosteronism. ...To …
The Cys Sense: Thiol Redox Switches Mediate Life Cycles of Cellular Proteins.
Radzinski M, Oppenheim T, Metanis N, Reichmann D. Radzinski M, et al. Biomolecules. 2021 Mar 22;11(3):469. doi: 10.3390/biom11030469. Biomolecules. 2021. PMID: 33809923 Free PMC article. Review.
At the heart of this process are redox-regulated proteins or thiol-based switches, which carefully mediate various steps of protein homeostasis across folding, localization, quality control, and degradation pathways. In this review, we discuss the "redox code" of the prote …
At the heart of this process are redox-regulated proteins or thiol-based switches, which carefully mediate various steps of protein h …
Thiol-disulfide exchange in signaling: disulfide bonds as a switch.
Messens J, Collet JF. Messens J, et al. Antioxid Redox Signal. 2013 May 1;18(13):1594-6. doi: 10.1089/ars.2012.5156. Epub 2013 Feb 25. Antioxid Redox Signal. 2013. PMID: 23330837
Over the last 30 years, a change in perspective took place driven by groundbreaking experiments, which promoted disulfide bonds to central players in essential thiol-disulfide exchange reactions involved in signal transduction, thiol protection, and redox homeostasi …
Over the last 30 years, a change in perspective took place driven by groundbreaking experiments, which promoted disulfide bonds to central p …
Silicon-Containing Thiol-Specific Bioconjugating Reagent.
Zhang Z, Li L, Xu H, Lee CK, Jia Z, Loh TP. Zhang Z, et al. J Am Chem Soc. 2024 Jan 24;146(3):1776-1782. doi: 10.1021/jacs.3c12050. Epub 2024 Jan 10. J Am Chem Soc. 2024. PMID: 38198597
A new bioconjugation reagent containing silicon has been developed for the selective reaction with thiols. The inclusion of silicon significantly improves chemoselectivity and suppresses retro processes, thereby exceeding the capabilities of traditional reagents. The metho …
A new bioconjugation reagent containing silicon has been developed for the selective reaction with thiols. The inclusion of silicon s …
Glutaredoxins in thiol/disulfide exchange.
Lillig CH, Berndt C. Lillig CH, et al. Antioxid Redox Signal. 2013 May 1;18(13):1654-65. doi: 10.1089/ars.2012.5007. Epub 2012 Dec 21. Antioxid Redox Signal. 2013. PMID: 23231445 Review.
SIGNIFICANCE: Glutaredoxins (Grxs) are small oxidoreductases of the thioredoxin family of proteins regulating the thiol redox state of several proteins. Thereby, Grxs are key elements in redox signaling. ...FUTURE DIRECTIONS: With this review, we provide a condensed summar …
SIGNIFICANCE: Glutaredoxins (Grxs) are small oxidoreductases of the thioredoxin family of proteins regulating the thiol redox state o …
Thiol signalling network with an eye to diabetes.
Matteucci E, Giampietro O. Matteucci E, et al. Molecules. 2010 Dec 6;15(12):8890-903. doi: 10.3390/molecules15128890. Molecules. 2010. PMID: 21135801 Free PMC article. Review.
The many oxidation states of sulphur are found in numerous sulphur species with distinct functional groups (thiols, disulphides, polysulphides, sulphenic, sulphinic and sulphonic acids, etc.), which participate in a complicated network of sulphur-based redox events. Human …
The many oxidation states of sulphur are found in numerous sulphur species with distinct functional groups (thiols, disulphides, poly …
139,511 results
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