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Page 1
Tenofovir alafenamide fumarate.
Lee WA, Cheng AK. Lee WA, et al. Antivir Ther. 2022 Apr;27(2):13596535211067600. doi: 10.1177/13596535211067600. Antivir Ther. 2022. PMID: 35499175 Free article.
Tenofovir alafenamide fumarate is a lipophilic prodrug of tenofovir which is preferentially metabolized in lymphatic tissue resulting in high concentrations of tenofovir (TFV) and its active diphosphate metabolite inside the cells that replicate HIV. Due to i …
Tenofovir alafenamide fumarate is a lipophilic prodrug of tenofovir which is preferentially metabolized in lymphatic tissue re …
Tenofovir Urine Assay to Monitor Adherence to HIV Pre-exposure Prophylaxis.
Moorthy GS, Lalley-Chareczko L, Koenig HC, Zuppa AF. Moorthy GS, et al. Curr Clin Pharmacol. 2020;15(2):102-104. doi: 10.2174/1574884714666191111125348. Curr Clin Pharmacol. 2020. PMID: 31713497 Review.
Tenofovir Disoproxil Fumarate (TDF) and tenofovir Alafenamide (TAF) are prodrugs of tenofovir and have excellent long-term efficacy and tolerability for the treatment of HIV. ...A semi-quantitative high-performance liquid chromatographymass spectrometry metho …
Tenofovir Disoproxil Fumarate (TDF) and tenofovir Alafenamide (TAF) are prodrugs of tenofovir and have excellent long-t …
Tenofovir and bone health.
Grant PM, Cotter AG. Grant PM, et al. Curr Opin HIV AIDS. 2016 May;11(3):326-32. doi: 10.1097/COH.0000000000000248. Curr Opin HIV AIDS. 2016. PMID: 26859637 Free PMC article. Review.
The aims of this review are to describe potential mechanisms underlying the adverse effects of tenofovir on bone, clinical studies of tenofovir disoproxil fumarate (TDF) and bone, and more recent bone data on tenofovir alafenamide. RECENT FINDING: Several stu …
The aims of this review are to describe potential mechanisms underlying the adverse effects of tenofovir on bone, clinical studies of …
Tenofovir alafenamide nephrotoxicity: a case report and literature review.
Ueaphongsukkit T, Gatechompol S, Avihingsanon A, Surintrspanont J, Iampenkhae K, Avihingsanon Y, Udomkarnjananun S. Ueaphongsukkit T, et al. AIDS Res Ther. 2021 Aug 21;18(1):53. doi: 10.1186/s12981-021-00380-w. AIDS Res Ther. 2021. PMID: 34419091 Free PMC article. Review.
BACKGROUND: Tenofovir alafenamide (TAF), a novel prodrug of tenofovir (TFV), has become the preferred drug for the treatment of HIV-1 and chronic hepatitis B infection in clinical practice. Results from clinical trials showed that it had better renal and bone minera …
BACKGROUND: Tenofovir alafenamide (TAF), a novel prodrug of tenofovir (TFV), has become the preferred drug for the treatment o …
Tenofovir alafenamide revisited.
Di Perri G. Di Perri G. Infez Med. 2020 Dec 1;28(4):525-533. Infez Med. 2020. PMID: 33257626 Free article.
Two Tenofovir pro-drugs are available for the treatment of HIV and HBV infection. Tenofovir Alafenamide (TAF) was clinically developed as a safer alternative to the older Tenofovir Disoproxil Fumarate (TDF) as the latter was consistently found to be associate …
Two Tenofovir pro-drugs are available for the treatment of HIV and HBV infection. Tenofovir Alafenamide (TAF) was clinically d …
Tenofovir for Prevention of HIV Infection.
Kaufman B, Zehtabchi S. Kaufman B, et al. Am Fam Physician. 2017 Jul 1;96(1):Online. Am Fam Physician. 2017. PMID: 28671379 Free article. Review. No abstract available.
Tenofovir alafenamide for the treatment of chronic hepatitis B virus infection.
Abdul Basit S, Dawood A, Ryan J, Gish R. Abdul Basit S, et al. Expert Rev Clin Pharmacol. 2017 Jul;10(7):707-716. doi: 10.1080/17512433.2017.1323633. Epub 2017 May 17. Expert Rev Clin Pharmacol. 2017. PMID: 28460547 Review.
In April 2017 tenofovir alafenamide (TAF) was added to the list of first-line therapies recommended for chronic hepatitis B (CHB). TAF has pharmacology similar to tenofovir disoproxil fumarate (TDF) with higher cell delivery to the hepatocytes but less systemic expo …
In April 2017 tenofovir alafenamide (TAF) was added to the list of first-line therapies recommended for chronic hepatitis B (CHB). TA …
Is Tenofovir Alafenamide Safer than Tenofovir Disoproxil Fumarate for the Kidneys?
Aloy B, Tazi I, Bagnis CI, Gauthier M, Janus N, Launay-Vacher V, Deray G, Tourret J. Aloy B, et al. AIDS Rev. 2016 Oct-Dec;18(4):184-192. AIDS Rev. 2016. PMID: 27438578 Free article. Review.
Tenofovir disoproxil fumarate is currently the cornerstone of HIV treatment. ...Pharmacokinetic studies suggest a better renal tolerance of tenofovir alafenamide than tenofovir disoproxil fumarate, probably because tenofovir plasma concentrations are l …
Tenofovir disoproxil fumarate is currently the cornerstone of HIV treatment. ...Pharmacokinetic studies suggest a better renal tolera …
Advancing HIV prevention using tenofovir-based pre-exposure prophylaxis.
Abdool Karim SS, Baxter C, Abdool Karim Q. Abdool Karim SS, et al. Antivir Ther. 2022 Apr;27(2):13596535211067589. doi: 10.1177/13596535211067589. Antivir Ther. 2022. PMID: 35499171 Free article.
Tenofovir-based pre-exposure prophylaxis (PrEP) revolutionized the global HIV prevention landscape. ...By 2021, 1.5 million people had initiated oral tenofovir-based PrEP, contributing to declines in HIV incidence in some regions. ...
Tenofovir-based pre-exposure prophylaxis (PrEP) revolutionized the global HIV prevention landscape. ...By 2021, 1.5 million people ha …
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