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Items: 1 to 20 of 319

1.

Response to BONE-D-15-01038.

Sánchez-Duffhues G, Hiepen C, Knaus P, Ten Dijke P.

Bone. 2016 Jan 26. pii: S8756-3282(16)30010-2. doi: 10.1016/j.bone.2016.01.022. [Epub ahead of print] No abstract available.

PMID:
26825814
2.

The Rationale for Targeting TGF-β in Chronic Liver Diseases.

Giannelli G, Mikulits W, Dooley S, Fabregat I, Moustakas A, Ten Dijke P, Portincasa P, Winter P, Janssen R, Leporatti S, Herrera B, Sanchez A.

Eur J Clin Invest. 2016 Jan 29. doi: 10.1111/eci.12596. [Epub ahead of print] Review.

PMID:
26823073
3.

TGF-β Signaling and Liver Disease.

Fabregat I, Moreno-Càceres J, Sánchez A, Dooley S, Dewidar B, Giannelli G, Ten Dijke P; IT-LIVER Consortium.

FEBS J. 2016 Jan 25. doi: 10.1111/febs.13665. [Epub ahead of print]

PMID:
26807763
4.

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva.

Cai J, Orlova VV, Cai X, Eekhoff EM, Zhang K, Pei D, Pan G, Mummery CL, Ten Dijke P.

Stem Cell Reports. 2015 Dec 8;5(6):963-70. doi: 10.1016/j.stemcr.2015.10.020. Epub 2015 Nov 26.

5.

Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels.

Ramnath NW, Hawinkels LJ, van Heijningen PM, Riet LT, Paauwe M, Vermeij M, Danser AH, Kanaar R, Ten Dijke P, Essers J.

Sci Rep. 2015 Nov 26;5:16872. doi: 10.1038/srep16872.

6.

Interrogating TGF-β Function and Regulation in Endothelial Cells.

Maring JA, van Meeteren LA, Goumans MJ, Ten Dijke P.

Methods Mol Biol. 2016;1344:193-203. doi: 10.1007/978-1-4939-2966-5_11.

PMID:
26520125
7.

Determining TGF-β Receptor Levels in the Cell Membrane.

Zhang L, Zhou F, van Dinther M, Ten Dijke P.

Methods Mol Biol. 2016;1344:35-47. doi: 10.1007/978-1-4939-2966-5_2.

PMID:
26520116
8.

Targeting BMP signalling in cardiovascular disease and anaemia.

Morrell NW, Bloch DB, Ten Dijke P, Goumans MJ, Hata A, Smith J, Yu PB, Bloch KD.

Nat Rev Cardiol. 2016 Feb;13(2):106-20. doi: 10.1038/nrcardio.2015.156. Epub 2015 Oct 13. Review.

PMID:
26461965
9.

In Brief: Endothelial-to-mesenchymal transition.

Sanchez-Duffhues G, Orlova V, Ten Dijke P.

J Pathol. 2016 Feb;238(3):378-80. doi: 10.1002/path.4653. Epub 2016 Jan 4.

PMID:
26446982
10.

Bone morphogenetic protein 6 and oxidized low-density lipoprotein synergistically recruit osteogenic differentiation in endothelial cells.

Yung LM, Sánchez-Duffhues G, Ten Dijke P, Yu PB.

Cardiovasc Res. 2015 Nov 1;108(2):278-87. doi: 10.1093/cvr/cvv221. Epub 2015 Sep 25.

PMID:
26410368
11.

Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice.

González-Núñez M, Riolobos AS, Castellano O, Fuentes-Calvo I, de los Ángeles Sevilla M, Oujo B, Pericacho M, Cruz-Gonzalez I, Pérez-Barriocanal F, ten Dijke P, López-Novoa JM.

Dis Model Mech. 2015 Nov;8(11):1427-39. doi: 10.1242/dmm.019695. Epub 2015 Sep 17.

12.

Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors.

Hawinkels LJ, de Vinuesa AG, Paauwe M, Kruithof-de Julio M, Wiercinska E, Pardali E, Mezzanotte L, Keereweer S, Braumuller TM, Heijkants RC, Jonkers J, Löwik CW, Goumans MJ, Ten Hagen TL, Ten Dijke P.

Clin Cancer Res. 2016 Jan 1;22(1):96-106. doi: 10.1158/1078-0432.CCR-15-0743. Epub 2015 Sep 15.

PMID:
26373572
13.

Bone morphogenetic protein signaling in bone homeostasis.

Sánchez-Duffhues G, Hiepen C, Knaus P, Ten Dijke P.

Bone. 2015 Nov;80:43-59. doi: 10.1016/j.bone.2015.05.025. Epub 2015 Jun 5. Review.

PMID:
26051467
14.

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins.

de Wilde AH, Wannee KF, Scholte FE, Goeman JJ, Ten Dijke P, Snijder EJ, Kikkert M, van Hemert MJ.

J Virol. 2015 Aug;89(16):8318-33. doi: 10.1128/JVI.01029-15. Epub 2015 Jun 3.

15.

Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models.

Li Y, Drabsch Y, Pujuguet P, Ren J, van Laar T, Zhang L, van Dam H, Clément-Lacroix P, Ten Dijke P.

Breast Cancer Res. 2015 Feb 25;17:28. doi: 10.1186/s13058-015-0537-8.

16.

Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2.

de Miranda NF, van Dinther M, van den Akker BE, van Wezel T, ten Dijke P, Morreau H.

Gastroenterology. 2015 Jun;148(7):1427-37.e8. doi: 10.1053/j.gastro.2015.02.052. Epub 2015 Feb 28.

PMID:
25736321
17.

Disorganised stroma determined on pre-treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial.

Dekker TJ, Charehbili A, Smit VT, ten Dijke P, Kranenbarg EM, van de Velde CJ, Nortier JW, Tollenaar RA, Mesker WE, Kroep JR.

Mol Oncol. 2015 Jun;9(6):1120-8. doi: 10.1016/j.molonc.2015.02.001. Epub 2015 Feb 14.

PMID:
25735561
18.

The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1.

van Caam A, Blaney Davidson E, Garcia de Vinuesa A, van Geffen E, van den Berg W, Goumans MJ, ten Dijke P, van der Kraan P.

Osteoarthritis Cartilage. 2015 Jun;23(6):985-95. doi: 10.1016/j.joca.2015.02.007. Epub 2015 Feb 12.

PMID:
25681563
19.

14-3-3ζ turns TGF-β to the dark side.

ten Dijke P, van Dam H.

Cancer Cell. 2015 Feb 9;27(2):151-3. doi: 10.1016/j.ccell.2015.01.005.

PMID:
25670073
20.

SLUG is expressed in endothelial cells lacking primary cilia to promote cellular calcification.

Sánchez-Duffhues G, de Vinuesa AG, Lindeman JH, Mulder-Stapel A, DeRuiter MC, Van Munsteren C, Goumans MJ, Hierck BP, Ten Dijke P.

Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):616-27. doi: 10.1161/ATVBAHA.115.305268. Epub 2015 Jan 29.

PMID:
25633317
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