Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1956 2
1957 1
1958 2
1959 3
1960 5
1961 3
1962 3
1963 3
1964 1
1965 1
1966 6
1967 9
1968 8
1969 5
1970 7
1971 10
1972 14
1973 4
1974 12
1975 70
1976 72
1977 64
1978 57
1979 48
1980 76
1981 73
1982 86
1983 103
1984 115
1985 116
1986 129
1987 133
1988 132
1989 132
1990 141
1991 152
1992 112
1993 136
1994 132
1995 152
1996 164
1997 155
1998 179
1999 177
2000 203
2001 210
2002 210
2003 266
2004 247
2005 265
2006 279
2007 332
2008 335
2009 358
2010 418
2011 504
2012 477
2013 641
2014 647
2015 700
2016 793
2017 867
2018 939
2019 1066
2020 1245
2021 1469
2022 1535
2023 1497
2024 661

Text availability

Article attribute

Article type

Publication date

Search Results

17,263 results

Results by year

Filters applied: . Clear all
Page 1
TCA precipitation.
Koontz L. Koontz L. Methods Enzymol. 2014;541:3-10. doi: 10.1016/B978-0-12-420119-4.00001-X. Methods Enzymol. 2014. PMID: 24674058
Trichloroacetic acid (TCA) precipitation of proteins is commonly used to concentrate protein samples or remove contaminants, including salts and detergents, prior to downstream applications such as SDS-PAGE or 2D-gels. TCA precipitation denatures the protein, so it …
Trichloroacetic acid (TCA) precipitation of proteins is commonly used to concentrate protein samples or remove contaminants, includin …
The functional roles of TCA cycle metabolites in cancer.
Eniafe J, Jiang S. Eniafe J, et al. Oncogene. 2021 May;40(19):3351-3363. doi: 10.1038/s41388-020-01639-8. Epub 2021 Apr 16. Oncogene. 2021. PMID: 33864000 Review.
The tricarboxylic acid cycle (TCA cycle) has been known for decades as a hub for generating cellular energy and precursors for biosynthetic pathways. ...In this review, we discuss the functional roles of the TCA cycle intermediates in suppressing or promoting the pr …
The tricarboxylic acid cycle (TCA cycle) has been known for decades as a hub for generating cellular energy and precursors for biosyn …
TCA Cycle Rewiring as Emerging Metabolic Signature of Hepatocellular Carcinoma.
Todisco S, Convertini P, Iacobazzi V, Infantino V. Todisco S, et al. Cancers (Basel). 2019 Dec 25;12(1):68. doi: 10.3390/cancers12010068. Cancers (Basel). 2019. PMID: 31881713 Free PMC article. Review.
In this review, we summarize the role of the TCA cycle rewiring in HCC by reporting gene expression and activity dysregulation of enzymes relating not only to the TCA cycle but also to glutamine metabolism, malate/aspartate, and citrate/pyruvate shuttles. Regarding …
In this review, we summarize the role of the TCA cycle rewiring in HCC by reporting gene expression and activity dysregulation of enz …
The Role of TCA Cycle Enzymes in Plants.
Zhang Y, Fernie AR. Zhang Y, et al. Adv Biol (Weinh). 2023 Aug;7(8):e2200238. doi: 10.1002/adbi.202200238. Epub 2023 Jun 21. Adv Biol (Weinh). 2023. PMID: 37341441 Review.
The alteration of TCA cycle enzyme expression results in changed plant growth and photosynthesis under controlled conditions. ...This article additionally highlights the recent finding that the plant TCA cycle, like that of mammals and microbes, dynamically assemble …
The alteration of TCA cycle enzyme expression results in changed plant growth and photosynthesis under controlled conditions. ...This …
Tricarboxylic Acid (TCA) Cycle Intermediates: Regulators of Immune Responses.
Choi I, Son H, Baek JH. Choi I, et al. Life (Basel). 2021 Jan 19;11(1):69. doi: 10.3390/life11010069. Life (Basel). 2021. PMID: 33477822 Free PMC article. Review.
In the eukaryotic system, the TCA cycle occurs completely in mitochondria, while the intermediates of the TCA cycle are retained inside mitochondria due to their polarity and hydrophilicity. ...Increasing evidence shows that the metabolites of the TCA cycle a …
In the eukaryotic system, the TCA cycle occurs completely in mitochondria, while the intermediates of the TCA cycle are retain …
Emerging Role of TCA Cycle-Related Enzymes in Human Diseases.
Kang W, Suzuki M, Saito T, Miyado K. Kang W, et al. Int J Mol Sci. 2021 Dec 2;22(23):13057. doi: 10.3390/ijms222313057. Int J Mol Sci. 2021. PMID: 34884868 Free PMC article. Review.
The tricarboxylic acid (TCA) cycle is the main source of cellular energy and participates in many metabolic pathways in cells. ...The diseases which develop as a consequence of loss or dysfunction of TCA cycle-related enzymes are distinct, suggesting that each enzym …
The tricarboxylic acid (TCA) cycle is the main source of cellular energy and participates in many metabolic pathways in cells. ...The …
Rescue of TCA Cycle Dysfunction for Cancer Therapy.
Marquez J, Flores J, Kim AH, Nyamaa B, Nguyen ATT, Park N, Han J. Marquez J, et al. J Clin Med. 2019 Dec 6;8(12):2161. doi: 10.3390/jcm8122161. J Clin Med. 2019. PMID: 31817761 Free PMC article. Review.
Mitochondrion, a maternally hereditary, subcellular organelle, is the site of the tricarboxylic acid (TCA) cycle, electron transport chain (ETC), and oxidative phosphorylation (OXPHOS)-the basic processes of ATP production. ...In this review, we explored the different sign …
Mitochondrion, a maternally hereditary, subcellular organelle, is the site of the tricarboxylic acid (TCA) cycle, electron transport …
The TCA cycle as a bridge between oncometabolism and DNA transactions in cancer.
Ciccarone F, Vegliante R, Di Leo L, Ciriolo MR. Ciccarone F, et al. Semin Cancer Biol. 2017 Dec;47:50-56. doi: 10.1016/j.semcancer.2017.06.008. Epub 2017 Jun 20. Semin Cancer Biol. 2017. PMID: 28645607 Review.
Thus, dysregulation of the TCA cycle flux is frequently observed in cancer. The identification of mutations in several enzymes of the TCA cycle in human tumours demonstrated a direct connection between this metabolic pathway and cancer occurrence. ...In this review, …
Thus, dysregulation of the TCA cycle flux is frequently observed in cancer. The identification of mutations in several enzymes of the …
Ins and Outs of the TCA Cycle: The Central Role of Anaplerosis.
Inigo M, Deja S, Burgess SC. Inigo M, et al. Annu Rev Nutr. 2021 Oct 11;41:19-47. doi: 10.1146/annurev-nutr-120420-025558. Epub 2021 Jul 16. Annu Rev Nutr. 2021. PMID: 34270333 Review.
The reactions of the tricarboxylic acid (TCA) cycle allow the controlled combustion of fat and carbohydrate. In principle, TCA cycle intermediates are regenerated on every turn and can facilitate the oxidation of an infinite number of nutrient molecules. ...
The reactions of the tricarboxylic acid (TCA) cycle allow the controlled combustion of fat and carbohydrate. In principle, TCA …
The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis.
Shen T, Wang H, Tang B, Zhu G, Wang X. Shen T, et al. RNA Biol. 2023 Jan;20(1):223-234. doi: 10.1080/15476286.2023.2216562. RNA Biol. 2023. PMID: 37221841 Free PMC article. Review.
The tricarboxylic acid (TCA) cycle is a central route for generating cellular energy and precursors for biosynthetic pathways. ...Interestingly, several TCA enzymes exhibit the characteristics of RNA binding properties, and their long non-coding RNA (lncRNA) partner …
The tricarboxylic acid (TCA) cycle is a central route for generating cellular energy and precursors for biosynthetic pathways. ...Int …
17,263 results
You have reached the last available page of results. Please see the User Guide for more information.

Searches related to "tca"