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Results: 1 to 20 of 85

1.

Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1.

Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL, Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM, James LI, Frye SV.

ACS Chem Biol. 2015 Jan 15. [Epub ahead of print]

PMID:
25590533
[PubMed - as supplied by publisher]
2.

Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.

Tong Q, Cui G, Botuyan MV, Rothbart SB, Hayashi R, Musselman CA, Singh N, Appella E, Strahl BD, Mer G, Kutateladze TG.

Structure. 2015 Jan 8. pii: S0969-2126(14)00406-7. doi: 10.1016/j.str.2014.11.013. [Epub ahead of print]

PMID:
25579814
[PubMed - as supplied by publisher]
3.

Product binding enforces the genomic specificity of a yeast polycomb repressive complex.

Dumesic PA, Homer CM, Moresco JJ, Pack LR, Shanle EK, Coyle SM, Strahl BD, Fujimori DG, Yates JR 3rd, Madhani HD.

Cell. 2015 Jan 15;160(1-2):204-18. doi: 10.1016/j.cell.2014.11.039. Epub 2014 Dec 18.

PMID:
25533783
[PubMed - in process]
4.

A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.

Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BC, Wade H, Tackett AJ, Strahl BD, Taverna SD.

Mol Cell Proteomics. 2014 Nov;13(11):2883-95. doi: 10.1074/mcp.M114.038224. Epub 2014 Aug 6.

PMID:
25104842
[PubMed - in process]
5.

SET-ting the stage for DNA repair.

Jha DK, Pfister SX, Humphrey TC, Strahl BD.

Nat Struct Mol Biol. 2014 Aug;21(8):655-7. doi: 10.1038/nsmb.2866. No abstract available.

PMID:
25093525
[PubMed - indexed for MEDLINE]
6.

Catalysis-dependent stabilization of Bre1 fine-tunes histone H2B ubiquitylation to regulate gene transcription.

Wozniak GG, Strahl BD.

Genes Dev. 2014 Aug 1;28(15):1647-52. doi: 10.1101/gad.243121.114.

PMID:
25085417
[PubMed - indexed for MEDLINE]
7.

Chromatin biochemistry enters the next generation of code 'seq-ing'.

Shanle EK, Rothbart SB, Strahl BD.

Nat Methods. 2014 Aug;11(8):799-800. doi: 10.1038/nmeth.3044. No abstract available.

PMID:
25075906
[PubMed - indexed for MEDLINE]
8.

An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair.

Jha DK, Strahl BD.

Nat Commun. 2014 Jun 9;5:3965. doi: 10.1038/ncomms4965.

PMID:
24910128
[PubMed - in process]
Free PMC Article
9.

A histone methylation network regulates transgenerational epigenetic memory in C. elegans.

Greer EL, Beese-Sims SE, Brookes E, Spadafora R, Zhu Y, Rothbart SB, Aristizábal-Corrales D, Chen S, Badeaux AI, Jin Q, Wang W, Strahl BD, Colaiácovo MP, Shi Y.

Cell Rep. 2014 Apr 10;7(1):113-26. doi: 10.1016/j.celrep.2014.02.044. Epub 2014 Mar 27.

PMID:
24685137
[PubMed - in process]
Free Article
10.

Hitting the 'mark': Interpreting lysine methylation in the context of active transcription.

Wozniak GG, Strahl BD.

Biochim Biophys Acta. 2014 Dec;1839(12):1353-1361. doi: 10.1016/j.bbagrm.2014.03.002. Epub 2014 Mar 12. Review.

PMID:
24631869
[PubMed - as supplied by publisher]
11.

Interpreting the language of histone and DNA modifications.

Rothbart SB, Strahl BD.

Biochim Biophys Acta. 2014 Aug;1839(8):627-43. doi: 10.1016/j.bbagrm.2014.03.001. Epub 2014 Mar 12. Review.

PMID:
24631868
[PubMed - indexed for MEDLINE]
12.

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function.

Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, Strahl BD, Bouhassira EE, Edelmann W, Keogh MC.

Cell Rep. 2014 Mar 13;6(5):892-905. doi: 10.1016/j.celrep.2014.01.029. Epub 2014 Feb 22.

PMID:
24565511
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.

Klein BJ, Piao L, Xi Y, Rincon-Arano H, Rothbart SB, Peng D, Wen H, Larson C, Zhang X, Zheng X, Cortazar MA, Peña PV, Mangan A, Bentley DL, Strahl BD, Groudine M, Li W, Shi X, Kutateladze TG.

Cell Rep. 2014 Jan 30;6(2):325-35. doi: 10.1016/j.celrep.2013.12.021. Epub 2014 Jan 9.

PMID:
24412361
[PubMed - indexed for MEDLINE]
Free Article
14.

A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation.

Dronamraju R, Strahl BD.

Nucleic Acids Res. 2014 Jan;42(2):870-81. doi: 10.1093/nar/gkt1003. Epub 2013 Oct 25.

PMID:
24163256
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue.

Kinkelin K, Wozniak GG, Rothbart SB, Lidschreiber M, Strahl BD, Cramer P.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15277-82. doi: 10.1073/pnas.1311010110. Epub 2013 Sep 3.

PMID:
24003114
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Recombinant antibodies to histone post-translational modifications.

Hattori T, Taft JM, Swist KM, Luo H, Witt H, Slattery M, Koide A, Ruthenburg AJ, Krajewski K, Strahl BD, White KP, Farnham PJ, Zhao Y, Koide S.

Nat Methods. 2013 Oct;10(10):992-5. doi: 10.1038/nmeth.2605. Epub 2013 Aug 18.

PMID:
23955773
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Stress-free with Rpd3: a unique chromatin complex mediates the response to oxidative stress.

McDaniel SL, Strahl BD.

Mol Cell Biol. 2013 Oct;33(19):3726-7. doi: 10.1128/MCB.01000-13. Epub 2013 Aug 12. No abstract available.

PMID:
23938299
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Dido3 PHD modulates cell differentiation and division.

Gatchalian J, Fütterer A, Rothbart SB, Tong Q, Rincon-Arano H, Sánchez de Diego A, Groudine M, Strahl BD, Martínez-A C, van Wely KH, Kutateladze TG.

Cell Rep. 2013 Jul 11;4(1):148-58. doi: 10.1016/j.celrep.2013.06.014. Epub 2013 Jul 3.

PMID:
23831028
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Molecular basis for chromatin binding and regulation of MLL5.

Ali M, Rincón-Arano H, Zhao W, Rothbart SB, Tong Q, Parkhurst SM, Strahl BD, Deng LW, Groudine M, Kutateladze TG.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11296-301. doi: 10.1073/pnas.1310156110. Epub 2013 Jun 24.

PMID:
23798402
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation.

Rothbart SB, Dickson BM, Ong MS, Krajewski K, Houliston S, Kireev DB, Arrowsmith CH, Strahl BD.

Genes Dev. 2013 Jun 1;27(11):1288-98. doi: 10.1101/gad.220467.113.

PMID:
23752590
[PubMed - indexed for MEDLINE]
Free PMC Article

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