Sort by

Send to

Choose Destination

Search results

Items: 1 to 20 of 30


Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.

Ikpa PT, Sleddens HF, Steinbrecher KA, Peppelenbosch MP, de Jonge HR, Smits R, Bijvelds MJ.

Histochem Cell Biol. 2016 May 31. [Epub ahead of print]


Natural compound methyl protodioscin protects against intestinal inflammation through modulation of intestinal immune responses.

Zhang R, Gilbert S, Yao X, Vallance J, Steinbrecher K, Moriggl R, Zhang D, Eluri M, Chen H, Cao H, Shroyer N, Denson L, Han X.

Pharmacol Res Perspect. 2015 Mar;3(2):e00118. doi: 10.1002/prp2.118. Epub 2015 Feb 10.


Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2.

Xin L, Jiang TT, Chaturvedi V, Kinder JM, Ertelt JM, Rowe JH, Steinbrecher KA, Way SS.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10672-7. doi: 10.1073/pnas.1402336111. Epub 2014 Jul 7.


Effect of guanylate cyclase-C activity on energy and glucose homeostasis.

Begg DP, Steinbrecher KA, Mul JD, Chambers AP, Kohli R, Haller A, Cohen MB, Woods SC, Seeley RJ.

Diabetes. 2014 Nov;63(11):3798-804. doi: 10.2337/db14-0160. Epub 2014 Jun 4.


Thrombin drives tumorigenesis in colitis-associated colon cancer.

Turpin B, Miller W, Rosenfeldt L, Kombrinck K, Flick MJ, Steinbrecher KA, Harmel-Laws E, Mullins ES, Shaw M, Witte DP, Revenko A, Monia B, Palumbo JS.

Cancer Res. 2014 Jun 1;74(11):3020-30. doi: 10.1158/0008-5472.CAN-13-3276. Epub 2014 Apr 7.


The multiple roles of guanylate cyclase C, a heat stable enterotoxin receptor.

Steinbrecher KA.

Curr Opin Gastroenterol. 2014 Jan;30(1):1-6. doi: 10.1097/MOG.0000000000000020. Review.


Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis.

Harmel-Laws E, Mann EA, Cohen MB, Steinbrecher KA.

PLoS One. 2013 Nov 11;8(11):e79180. doi: 10.1371/journal.pone.0079180. eCollection 2013.


Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection.

Elahi S, Ertelt JM, Kinder JM, Jiang TT, Zhang X, Xin L, Chaturvedi V, Strong BS, Qualls JE, Steinbrecher KA, Kalfa TA, Shaaban AF, Way SS.

Nature. 2013 Dec 5;504(7478):158-62. doi: 10.1038/nature12675. Epub 2013 Nov 6.


IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice.

Harley IT, Stankiewicz TE, Giles DA, Softic S, Flick LM, Cappelletti M, Sheridan R, Xanthakos SA, Steinbrecher KA, Sartor RB, Kohli R, Karp CL, Divanovic S.

Hepatology. 2014 May;59(5):1830-9. doi: 10.1002/hep.26746. Epub 2014 Mar 27.


Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.

Mann EA, Harmel-Laws E, Cohen MB, Steinbrecher KA.

BMC Gastroenterol. 2013 Sep 2;13:135. doi: 10.1186/1471-230X-13-135.


Inflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation.

Du W, Amarachintha S, Sipple J, Schick J, Steinbrecher K, Pang Q.

J Immunol. 2013 Sep 1;191(5):2806-17. doi: 10.4049/jimmunol.1203474. Epub 2013 Aug 7.


Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.

Waddell A, Ahrens R, Tsai YT, Sherrill JD, Denson LA, Steinbrecher KA, Hogan SP.

J Immunol. 2013 May 1;190(9):4773-85. doi: 10.4049/jimmunol.1200057. Epub 2013 Apr 5.


Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation.

Gilbert S, Zhang R, Denson L, Moriggl R, Steinbrecher K, Shroyer N, Lin J, Han X.

EMBO Mol Med. 2012 Feb;4(2):109-24. doi: 10.1002/emmm.201100192. Epub 2012 Jan 9.


Murine guanylate cyclase C regulates colonic injury and inflammation.

Steinbrecher KA, Harmel-Laws E, Garin-Laflam MP, Mann EA, Bezerra LD, Hogan SP, Cohen MB.

J Immunol. 2011 Jun 15;186(12):7205-14. doi: 10.4049/jimmunol.1002469. Epub 2011 May 9.


Colonic eosinophilic inflammation in experimental colitis is mediated by Ly6C(high) CCR2(+) inflammatory monocyte/macrophage-derived CCL11.

Waddell A, Ahrens R, Steinbrecher K, Donovan B, Rothenberg ME, Munitz A, Hogan SP.

J Immunol. 2011 May 15;186(10):5993-6003. doi: 10.4049/jimmunol.1003844. Epub 2011 Apr 15.


Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.

Han X, Mann E, Gilbert S, Guan Y, Steinbrecher KA, Montrose MH, Cohen MB.

PLoS One. 2011 Jan 31;6(1):e16139. doi: 10.1371/journal.pone.0016139.


Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.

Wu D, Ahrens R, Osterfeld H, Noah TK, Groschwitz K, Foster PS, Steinbrecher KA, Rothenberg ME, Shroyer NF, Matthaei KI, Finkelman FD, Hogan SP.

J Biol Chem. 2011 Apr 15;286(15):13357-69. doi: 10.1074/jbc.M110.214965. Epub 2011 Feb 8.


Transmembrane guanylate cyclase in intestinal pathophysiology.

Steinbrecher KA, Cohen MB.

Curr Opin Gastroenterol. 2011 Mar;27(2):139-45. doi: 10.1097/MOG.0b013e328341ead5. Review.


Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis.

Munitz A, Cole ET, Beichler A, Groschwitz K, Ahrens R, Steinbrecher K, Willson T, Han X, Denson L, Rothenberg ME, Hogan SP.

Gastroenterology. 2010 Aug;139(2):530-41. doi: 10.1053/j.gastro.2010.04.006. Epub 2010 Apr 14.


Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen.

Steinbrecher KA, Horowitz NA, Blevins EA, Barney KA, Shaw MA, Harmel-Laws E, Finkelman FD, Flick MJ, Pinkerton MD, Talmage KE, Kombrinck KW, Witte DP, Palumbo JS.

Cancer Res. 2010 Apr 1;70(7):2634-43. doi: 10.1158/0008-5472.CAN-09-3465. Epub 2010 Mar 16.

Items per page

Supplemental Content

Loading ...
Write to the Help Desk