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Items: 1 to 20 of 67

1.

Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program.

Shao M, Ishibashi J, Kusminski CM, Wang QA, Hepler C, Vishvanath L, MacPherson KA, Spurgin SB, Sun K, Holland WL, Seale P, Gupta RK.

Cell Metab. 2016 Jun 14;23(6):1167-84. doi: 10.1016/j.cmet.2016.04.023. Epub 2016 May 26.

PMID:
27238639
2.

Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue.

Tran CM, Mukherjee S, Ye L, Frederick DW, Kissig M, Davis JG, Lamming DW, Seale P, Baur JA.

Diabetes. 2016 Apr;65(4):927-41. doi: 10.2337/db15-0502. Epub 2016 Feb 8.

PMID:
26858361
3.

EBF2 promotes the recruitment of beige adipocytes in white adipose tissue.

Stine RR, Shapira SN, Lim HW, Ishibashi J, Harms M, Won KJ, Seale P.

Mol Metab. 2015 Nov 14;5(1):57-65. doi: 10.1016/j.molmet.2015.11.001. eCollection 2016 Jan.

4.

Brown and Beige Fat: Physiological Roles beyond Heat Generation.

Kajimura S, Spiegelman BM, Seale P.

Cell Metab. 2015 Oct 6;22(4):546-59. doi: 10.1016/j.cmet.2015.09.007. Review.

PMID:
26445512
5.

Single-cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis.

Spaethling JM, Sanchez-Alavez M, Lee J, Xia FC, Dueck H, Wang W, Fisher SA, Sul JY, Seale P, Kim J, Bartfai T, Eberwine J.

FASEB J. 2016 Jan;30(1):81-92. doi: 10.1096/fj.15-273797. Epub 2015 Aug 24.

PMID:
26304220
6.

Multidrug-resistant tuberculosis in New South Wales, Australia, 1999-2010: a case series report.

Roberts-Witteveen A, Reinten T, Christensen A, Sintchenko V, Seale P, Lowbridge C.

Int J Tuberc Lung Dis. 2015 Jul;19(7):850-6. doi: 10.5588/ijtld.14.0575.

PMID:
26056113
7.

Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation.

Dueck H, Khaladkar M, Kim TK, Spaethling JM, Francis C, Suresh S, Fisher SA, Seale P, Beck SG, Bartfai T, Kuhn B, Eberwine J, Kim J.

Genome Biol. 2015 Jun 9;16:122. doi: 10.1186/s13059-015-0683-4.

8.

Transcriptional Regulatory Circuits Controlling Brown Fat Development and Activation.

Seale P.

Diabetes. 2015 Jul;64(7):2369-75. doi: 10.2337/db15-0203. Epub 2015 Jun 7. Review.

9.

The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin.

DiPilato LM, Ahmad F, Harms M, Seale P, Manganiello V, Birnbaum MJ.

Mol Cell Biol. 2015 Aug;35(16):2752-60. doi: 10.1128/MCB.00422-15. Epub 2015 Jun 1.

10.

PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.

Harms MJ, Lim HW, Ho Y, Shapira SN, Ishibashi J, Rajakumari S, Steger DJ, Lazar MA, Won KJ, Seale P.

Genes Dev. 2015 Feb 1;29(3):298-307. doi: 10.1101/gad.252734.114.

11.

Functions of Prdm16 in thermogenic fat cells.

Ishibashi J, Seale P.

Temperature (Austin). 2015 Mar 17;2(1):65-72. doi: 10.4161/23328940.2014.974444. eCollection 2015 Jan-Mar. Review.

12.

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D.

Nature. 2015 Mar 12;519(7542):242-6. doi: 10.1038/nature14115. Epub 2014 Dec 22.

13.

Thermogenic activity of UCP1 in human white fat-derived beige adipocytes.

Bartesaghi S, Hallen S, Huang L, Svensson PA, Momo RA, Wallin S, Carlsson EK, Forslöw A, Seale P, Peng XR.

Mol Endocrinol. 2015 Jan;29(1):130-9. doi: 10.1210/me.2014-1295.

PMID:
25389910
14.

Ebf2 is a selective marker of brown and beige adipogenic precursor cells.

Wang W, Kissig M, Rajakumari S, Huang L, Lim HW, Won KJ, Seale P.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14466-71. doi: 10.1073/pnas.1412685111. Epub 2014 Sep 2.

15.

Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis.

Lim MA, Bence KK, Sandesara I, Andreux P, Auwerx J, Ishibashi J, Seale P, Kalb RG.

Hum Mol Genet. 2014 Sep 15;23(18):4995-5008. doi: 10.1093/hmg/ddu214. Epub 2014 May 15.

16.

Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.

Harms MJ, Ishibashi J, Wang W, Lim HW, Goyama S, Sato T, Kurokawa M, Won KJ, Seale P.

Cell Metab. 2014 Apr 1;19(4):593-604. doi: 10.1016/j.cmet.2014.03.007.

17.

p107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells.

De Sousa M, Porras DP, Perry CG, Seale P, Scimè A.

Stem Cells. 2014 May;32(5):1323-36. doi: 10.1002/stem.1637.

18.

Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.

Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, Kajimura S, Piston DW, Mathis D, Cinti S, Shulman GI, Seale P, Spiegelman BM.

Cell. 2014 Jan 16;156(1-2):304-16. doi: 10.1016/j.cell.2013.12.021.

19.

The nuclear receptor Rev-erbα controls circadian thermogenic plasticity.

Gerhart-Hines Z, Feng D, Emmett MJ, Everett LJ, Loro E, Briggs ER, Bugge A, Hou C, Ferrara C, Seale P, Pryma DA, Khurana TS, Lazar MA.

Nature. 2013 Nov 21;503(7476):410-3. doi: 10.1038/nature12642. Epub 2013 Oct 27.

20.

Brown and beige fat: development, function and therapeutic potential.

Harms M, Seale P.

Nat Med. 2013 Oct;19(10):1252-63. doi: 10.1038/nm.3361. Epub 2013 Sep 29. Review.

PMID:
24100998
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