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Results: 1 to 20 of 55

1.

Thermogenic Activity of UCP1 in Human White Fat-Derived Beige Adipocytes.

Bartesaghi S, Hallen S, Huang L, Svensson PA, Momo RA, Wallin S, Carlsson EK, Forslöw A, Seale P, Peng XR.

Mol Endocrinol. 2014 Nov 12:me20141295. [Epub ahead of print]

PMID:
25389910
[PubMed - as supplied by publisher]
2.

Ebf2 is a selective marker of brown and beige adipogenic precursor cells.

Wang W, Kissig M, Rajakumari S, Huang L, Lim HW, Won KJ, Seale P.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14466-71. doi: 10.1073/pnas.1412685111. Epub 2014 Sep 2.

PMID:
25197048
[PubMed - in process]
3.

Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis.

Lim MA, Bence KK, Sandesara I, Andreux P, Auwerx J, Ishibashi J, Seale P, Kalb RG.

Hum Mol Genet. 2014 Sep 15;23(18):4995-5008. doi: 10.1093/hmg/ddu214. Epub 2014 May 15.

PMID:
24833719
[PubMed - in process]
4.

Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.

Harms MJ, Ishibashi J, Wang W, Lim HW, Goyama S, Sato T, Kurokawa M, Won KJ, Seale P.

Cell Metab. 2014 Apr 1;19(4):593-604. doi: 10.1016/j.cmet.2014.03.007.

PMID:
24703692
[PubMed - in process]
5.

p107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells.

De Sousa M, Porras DP, Perry CG, Seale P, Scimè A.

Stem Cells. 2014 May;32(5):1323-36. doi: 10.1002/stem.1637.

PMID:
24449206
[PubMed - in process]
6.

Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.

Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, Kajimura S, Piston DW, Mathis D, Cinti S, Shulman GI, Seale P, Spiegelman BM.

Cell. 2014 Jan 16;156(1-2):304-16. doi: 10.1016/j.cell.2013.12.021.

PMID:
24439384
[PubMed - indexed for MEDLINE]
7.

The nuclear receptor Rev-erbα controls circadian thermogenic plasticity.

Gerhart-Hines Z, Feng D, Emmett MJ, Everett LJ, Loro E, Briggs ER, Bugge A, Hou C, Ferrara C, Seale P, Pryma DA, Khurana TS, Lazar MA.

Nature. 2013 Nov 21;503(7476):410-3. doi: 10.1038/nature12642. Epub 2013 Oct 27.

PMID:
24162845
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Brown and beige fat: development, function and therapeutic potential.

Harms M, Seale P.

Nat Med. 2013 Oct;19(10):1252-63. doi: 10.1038/nm.3361. Epub 2013 Sep 29. Review.

PMID:
24100998
[PubMed - indexed for MEDLINE]
9.

Brown adipose tissue biology and therapeutic potential.

Seale P.

Front Endocrinol (Lausanne). 2013 Mar 19;4:14. doi: 10.3389/fendo.2013.00014. eCollection 2013. No abstract available.

PMID:
23513074
[PubMed]
Free PMC Article
10.

EBF2 determines and maintains brown adipocyte identity.

Rajakumari S, Wu J, Ishibashi J, Lim HW, Giang AH, Won KJ, Reed RR, Seale P.

Cell Metab. 2013 Apr 2;17(4):562-74. doi: 10.1016/j.cmet.2013.01.015. Epub 2013 Mar 14.

PMID:
23499423
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16.

Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F, Dekemp RA, Boushel R, Harper ME, Rudnicki MA.

Cell Metab. 2013 Feb 5;17(2):210-24. doi: 10.1016/j.cmet.2013.01.004.

PMID:
23395168
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity.

Derecka M, Gornicka A, Koralov SB, Szczepanek K, Morgan M, Raje V, Sisler J, Zhang Q, Otero D, Cichy J, Rajewsky K, Shimoda K, Poli V, Strobl B, Pellegrini S, Harris TE, Seale P, Russell AP, McAinch AJ, O'Brien PE, Keller SR, Croniger CM, Kordula T, Larner AC.

Cell Metab. 2012 Dec 5;16(6):814-24. doi: 10.1016/j.cmet.2012.11.005.

PMID:
23217260
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

An Evi1-C/EBPβ complex controls peroxisome proliferator-activated receptor γ2 gene expression to initiate white fat cell differentiation.

Ishibashi J, Firtina Z, Rajakumari S, Wood KH, Conroe HM, Steger DJ, Seale P.

Mol Cell Biol. 2012 Jun;32(12):2289-99. doi: 10.1128/MCB.06529-11. Epub 2012 Apr 2.

PMID:
22473998
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Orexin turns up the heat on obesity.

Seale P.

Cell Metab. 2011 Oct 5;14(4):441-2. doi: 10.1016/j.cmet.2011.09.007.

PMID:
21982704
[PubMed]
Free Article
15.

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.

Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM.

J Clin Invest. 2011 Jan;121(1):96-105. doi: 10.1172/JCI44271. Epub 2010 Dec 1.

PMID:
21123942
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Transcriptional control of brown adipocyte development and thermogenesis.

Seale P.

Int J Obes (Lond). 2010 Oct;34 Suppl 1:S17-22. doi: 10.1038/ijo.2010.178.

PMID:
20935660
[PubMed - indexed for MEDLINE]
17.

Validity of a continuous metabolic risk score as an index for modeling metabolic syndrome in adolescents.

Okosun IS, Lyn R, Davis-Smith M, Eriksen M, Seale P.

Ann Epidemiol. 2010 Nov;20(11):843-51. doi: 10.1016/j.annepidem.2010.08.001.

PMID:
20933191
[PubMed - indexed for MEDLINE]
18.

Medicine. Beige can be slimming.

Ishibashi J, Seale P.

Science. 2010 May 28;328(5982):1113-4. doi: 10.1126/science.1190816. Epub 2010 May 6. No abstract available.

PMID:
20448151
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Transcriptional control of brown fat development.

Kajimura S, Seale P, Spiegelman BM.

Cell Metab. 2010 Apr 7;11(4):257-62. doi: 10.1016/j.cmet.2010.03.005. Review.

PMID:
20374957
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Transcriptional control of preadipocyte determination by Zfp423.

Gupta RK, Arany Z, Seale P, Mepani RJ, Ye L, Conroe HM, Roby YA, Kulaga H, Reed RR, Spiegelman BM.

Nature. 2010 Mar 25;464(7288):619-23. doi: 10.1038/nature08816. Epub 2010 Mar 3.

PMID:
20200519
[PubMed - indexed for MEDLINE]
Free PMC Article

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