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Results: 1 to 20 of 64

1.

Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals.

Barral S, Reitz C, Small SA, Mayeux R.

Neurobiol Aging. 2014 Jun 28. pii: S0197-4580(14)00462-X. doi: 10.1016/j.neurobiolaging.2014.06.024. [Epub ahead of print]

PMID:
25150575
[PubMed - as supplied by publisher]
2.

Pharmacological chaperones in the age of proteomic pathology.

Small SA.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12274-5. doi: 10.1073/pnas.1413111111. Epub 2014 Aug 13. No abstract available.

PMID:
25122676
[PubMed - in process]
3.

Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition.

Gilani AI, Chohan MO, Inan M, Schobel SA, Chaudhury NH, Paskewitz S, Chuhma N, Glickstein S, Merker RJ, Xu Q, Small SA, Anderson SA, Ross ME, Moore H.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7450-5. doi: 10.1073/pnas.1316488111. Epub 2014 May 2.

PMID:
24794528
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pharmacological chaperones stabilize retromer to limit APP processing.

Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA.

Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508. Epub 2014 Apr 20.

PMID:
24747528
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease.

Morabito MV, Berman DE, Schneider RT, Zhang Y, Leibel RL, Small SA.

Neurobiol Dis. 2014 May;65:188-92. doi: 10.1016/j.nbd.2013.12.017. Epub 2014 Jan 14.

PMID:
24440570
[PubMed - in process]
6.

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease.

Khan UA, Liu L, Provenzano FA, Berman DE, Profaci CP, Sloan R, Mayeux R, Duff KE, Small SA.

Nat Neurosci. 2014 Feb;17(2):304-11. doi: 10.1038/nn.3606. Epub 2013 Dec 22.

PMID:
24362760
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48.

Pavlopoulos E, Jones S, Kosmidis S, Close M, Kim C, Kovalerchik O, Small SA, Kandel ER.

Sci Transl Med. 2013 Aug 28;5(200):200ra115. doi: 10.1126/scitranslmed.3006373.

PMID:
23986399
[PubMed - indexed for MEDLINE]
Free Article
8.

Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.

Morel E, Chamoun Z, Lasiecka ZM, Chan RB, Williamson RL, Vetanovetz C, Dall'Armi C, Simoes S, Point Du Jour KS, McCabe BD, Small SA, Di Paolo G.

Nat Commun. 2013;4:2250. doi: 10.1038/ncomms3250.

PMID:
23907271
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver.

Schobel SA, Chaudhury NH, Khan UA, Paniagua B, Styner MA, Asllani I, Inbar BP, Corcoran CM, Lieberman JA, Moore H, Small SA.

Neuron. 2013 Apr 10;78(1):81-93. doi: 10.1016/j.neuron.2013.02.011.

PMID:
23583108
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.

MacLeod DA, Rhinn H, Kuwahara T, Zolin A, Di Paolo G, McCabe BD, Marder KS, Honig LS, Clark LN, Small SA, Abeliovich A.

Neuron. 2013 Feb 6;77(3):425-39. doi: 10.1016/j.neuron.2012.11.033. Erratum in: Neuron. 2013 Mar 6;77(5):994. MacCabe, Brian D [corrected to McCabe, Brian D].

PMID:
23395371
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Regional vulnerability in Huntington's disease: fMRI-guided molecular analysis in patients and a mouse model of disease.

Lewandowski NM, Bordelon Y, Brickman AM, Angulo S, Khan U, Muraskin J, Griffith EY, Wasserman P, Menalled L, Vonsattel JP, Marder K, Small SA, Moreno H.

Neurobiol Dis. 2013 Apr;52:84-93. doi: 10.1016/j.nbd.2012.11.014. Epub 2012 Dec 4. Erratum in: Neurobiol Dis. 2013 Jun;54:115.

PMID:
23220414
[PubMed - indexed for MEDLINE]
12.

Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes.

Lane RF, St George-Hyslop P, Hempstead BL, Small SA, Strittmatter SM, Gandy S.

J Neurosci. 2012 Oct 10;32(41):14080-6. doi: 10.1523/JNEUROSCI.3359-12.2012. Review.

PMID:
23055476
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

R6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures.

Cepeda-Prado E, Popp S, Khan U, Stefanov D, Rodríguez J, Menalled LB, Dow-Edwards D, Small SA, Moreno H.

J Neurosci. 2012 May 9;32(19):6456-67. doi: 10.1523/JNEUROSCI.0388-12.2012.

PMID:
22573668
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mechanisms of age-related cognitive change and targets for intervention: epigenetics.

Kosik KS, Rapp PR, Raz N, Small SA, Sweatt JD, Tsai LH.

J Gerontol A Biol Sci Med Sci. 2012 Jun;67(7):741-6. doi: 10.1093/gerona/gls110. Epub 2012 Apr 20. Review.

PMID:
22522509
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport.

Bhalla A, Vetanovetz CP, Morel E, Chamoun Z, Di Paolo G, Small SA.

Neurobiol Dis. 2012 Jul;47(1):126-34. doi: 10.1016/j.nbd.2012.03.030. Epub 2012 Apr 6.

PMID:
22516235
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Motor deficits correlate with resting state motor network connectivity in patients with brain tumours.

Otten ML, Mikell CB, Youngerman BE, Liston C, Sisti MB, Bruce JN, Small SA, McKhann GM 2nd.

Brain. 2012 Apr;135(Pt 4):1017-26. doi: 10.1093/brain/aws041. Epub 2012 Mar 8.

PMID:
22408270
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles.

Baseri B, Choi JJ, Deffieux T, Samiotaki G, Tung YS, Olumolade O, Small SA, Morrison B, Konofagou EE.

Phys Med Biol. 2012 Apr 7;57(7):N65-81. doi: 10.1088/0031-9155/57/7/N65. Epub 2012 Mar 9.

PMID:
22407323
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Depressive symptoms, antidepressant use, and brain volumes on MRI in a population-based cohort of old persons without dementia.

Geerlings MI, Brickman AM, Schupf N, Devanand DP, Luchsinger JA, Mayeux R, Small SA.

J Alzheimers Dis. 2012;30(1):75-82. doi: 10.3233/JAD-2012-112009.

PMID:
22377782
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Trans-synaptic spread of tau pathology in vivo.

Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, Duff K.

PLoS One. 2012;7(2):e31302. doi: 10.1371/journal.pone.0031302. Epub 2012 Feb 1.

PMID:
22312444
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Alzheimer's disease.

Gazzaley A, Small SA.

Network. 2011;22(1-4):173-85. doi: 10.3109/0954898X.2011.638696. Review. No abstract available.

PMID:
22149678
[PubMed - indexed for MEDLINE]

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