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Results: 1 to 20 of 68

1.

Retromer in Alzheimer disease, Parkinson disease and other neurological disorders.

Small SA, Petsko GA.

Nat Rev Neurosci. 2015 Mar;16(3):126-32. doi: 10.1038/nrn3896. Epub 2015 Feb 11. Review.

PMID:
25669742
2.

The use of pharmacological retromer chaperones in Alzheimer's disease and other endosomal-related disorders.

Berman DE, Ringe D, Petsko GA, Small SA.

Neurotherapeutics. 2015 Jan;12(1):12-8. doi: 10.1007/s13311-014-0321-y.

PMID:
25472693
3.

Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults.

Brickman AM, Khan UA, Provenzano FA, Yeung LK, Suzuki W, Schroeter H, Wall M, Sloan RP, Small SA.

Nat Neurosci. 2014 Dec;17(12):1798-803. doi: 10.1038/nn.3850. Epub 2014 Oct 26.

4.

Isolating pathogenic mechanisms embedded within the hippocampal circuit through regional vulnerability.

Small SA.

Neuron. 2014 Oct 1;84(1):32-9. doi: 10.1016/j.neuron.2014.08.030. Review.

PMID:
25277453
5.

Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals.

Barral S, Reitz C, Small SA, Mayeux R.

Neurobiol Aging. 2014 Dec;35(12):2881.e7-2881.e10. doi: 10.1016/j.neurobiolaging.2014.06.024. Epub 2014 Jun 28.

6.

Pharmacological chaperones in the age of proteomic pathology.

Small SA.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12274-5. doi: 10.1073/pnas.1413111111. Epub 2014 Aug 13. No abstract available.

7.

Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition.

Gilani AI, Chohan MO, Inan M, Schobel SA, Chaudhury NH, Paskewitz S, Chuhma N, Glickstein S, Merker RJ, Xu Q, Small SA, Anderson SA, Ross ME, Moore H.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7450-5. doi: 10.1073/pnas.1316488111. Epub 2014 May 2.

8.

Pharmacological chaperones stabilize retromer to limit APP processing.

Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA.

Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508. Epub 2014 Apr 20.

9.

Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease.

Morabito MV, Berman DE, Schneider RT, Zhang Y, Leibel RL, Small SA.

Neurobiol Dis. 2014 May;65:188-92. doi: 10.1016/j.nbd.2013.12.017. Epub 2014 Jan 14.

10.

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease.

Khan UA, Liu L, Provenzano FA, Berman DE, Profaci CP, Sloan R, Mayeux R, Duff KE, Small SA.

Nat Neurosci. 2014 Feb;17(2):304-11. doi: 10.1038/nn.3606. Epub 2013 Dec 22.

11.

Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48.

Pavlopoulos E, Jones S, Kosmidis S, Close M, Kim C, Kovalerchik O, Small SA, Kandel ER.

Sci Transl Med. 2013 Aug 28;5(200):200ra115. doi: 10.1126/scitranslmed.3006373.

12.

Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.

Morel E, Chamoun Z, Lasiecka ZM, Chan RB, Williamson RL, Vetanovetz C, Dall'Armi C, Simoes S, Point Du Jour KS, McCabe BD, Small SA, Di Paolo G.

Nat Commun. 2013;4:2250. doi: 10.1038/ncomms3250.

13.

Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver.

Schobel SA, Chaudhury NH, Khan UA, Paniagua B, Styner MA, Asllani I, Inbar BP, Corcoran CM, Lieberman JA, Moore H, Small SA.

Neuron. 2013 Apr 10;78(1):81-93. doi: 10.1016/j.neuron.2013.02.011.

14.

RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.

MacLeod DA, Rhinn H, Kuwahara T, Zolin A, Di Paolo G, McCabe BD, Marder KS, Honig LS, Clark LN, Small SA, Abeliovich A.

Neuron. 2013 Feb 6;77(3):425-39. doi: 10.1016/j.neuron.2012.11.033. Erratum in: Neuron. 2013 Mar 6;77(5):994. MacCabe, Brian D [corrected to McCabe, Brian D].

15.

Regional vulnerability in Huntington's disease: fMRI-guided molecular analysis in patients and a mouse model of disease.

Lewandowski NM, Bordelon Y, Brickman AM, Angulo S, Khan U, Muraskin J, Griffith EY, Wasserman P, Menalled L, Vonsattel JP, Marder K, Small SA, Moreno H.

Neurobiol Dis. 2013 Apr;52:84-93. doi: 10.1016/j.nbd.2012.11.014. Epub 2012 Dec 4. Erratum in: Neurobiol Dis. 2013 Jun;54:115.

16.

Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes.

Lane RF, St George-Hyslop P, Hempstead BL, Small SA, Strittmatter SM, Gandy S.

J Neurosci. 2012 Oct 10;32(41):14080-6. doi: 10.1523/JNEUROSCI.3359-12.2012. Review.

17.

R6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures.

Cepeda-Prado E, Popp S, Khan U, Stefanov D, Rodríguez J, Menalled LB, Dow-Edwards D, Small SA, Moreno H.

J Neurosci. 2012 May 9;32(19):6456-67. doi: 10.1523/JNEUROSCI.0388-12.2012.

18.

Mechanisms of age-related cognitive change and targets for intervention: epigenetics.

Kosik KS, Rapp PR, Raz N, Small SA, Sweatt JD, Tsai LH.

J Gerontol A Biol Sci Med Sci. 2012 Jun;67(7):741-6. doi: 10.1093/gerona/gls110. Epub 2012 Apr 20. Review.

19.

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport.

Bhalla A, Vetanovetz CP, Morel E, Chamoun Z, Di Paolo G, Small SA.

Neurobiol Dis. 2012 Jul;47(1):126-34. doi: 10.1016/j.nbd.2012.03.030. Epub 2012 Apr 6.

20.

Motor deficits correlate with resting state motor network connectivity in patients with brain tumours.

Otten ML, Mikell CB, Youngerman BE, Liston C, Sisti MB, Bruce JN, Small SA, McKhann GM 2nd.

Brain. 2012 Apr;135(Pt 4):1017-26. doi: 10.1093/brain/aws041. Epub 2012 Mar 8.

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