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PINK1- and PARK2-mediated local mitophagy in distal neuronal axons.

Ashrafi G, Schwarz TL.

Autophagy. 2015;11(1):187-9. doi: 10.1080/15548627.2014.996021.


Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin.

Ashrafi G, Schlehe JS, LaVoie MJ, Schwarz TL.

J Cell Biol. 2014 Sep 1;206(5):655-70. doi: 10.1083/jcb.201401070. Epub 2014 Aug 25.


Glucose regulates mitochondrial motility via Milton modification by O-GlcNAc transferase.

Pekkurnaz G, Trinidad JC, Wang X, Kong D, Schwarz TL.

Cell. 2014 Jul 3;158(1):54-68. doi: 10.1016/j.cell.2014.06.007.


Have you seen? For parkin, it's not all or nothing.

Shlevkov E, Schwarz TL.

EMBO J. 2014 Feb 18;33(4):277-9. doi: 10.1002/embj.201387723. Epub 2014 Feb 5. No abstract available.


The paradox of paclitaxel neurotoxicity: Mechanisms and unanswered questions.

Gornstein E, Schwarz TL.

Neuropharmacology. 2014 Jan;76 Pt A:175-83. doi: 10.1016/j.neuropharm.2013.08.016. Epub 2013 Aug 24. Review.


Ral mediates activity-dependent growth of postsynaptic membranes via recruitment of the exocyst.

Teodoro RO, Pekkurnaz G, Nasser A, Higashi-Kovtun ME, Balakireva M, McLachlan IG, Camonis J, Schwarz TL.

EMBO J. 2013 Jul 17;32(14):2039-55. doi: 10.1038/emboj.2013.147. Epub 2013 Jun 28. Erratum in: EMBO J. 2013 Aug 28;32(17):2418-9.


Mitochondrial trafficking in neurons.

Schwarz TL.

Cold Spring Harb Perspect Biol. 2013 Jun 1;5(6). pii: a011304. doi: 10.1101/cshperspect.a011304. Review.


The pathways of mitophagy for quality control and clearance of mitochondria.

Ashrafi G, Schwarz TL.

Cell Death Differ. 2013 Jan;20(1):31-42. doi: 10.1038/cdd.2012.81. Epub 2012 Jun 29. Review.


The CAP-Gly of p150: one domain, two diseases, and a function at the end.

Cronin MA, Schwarz TL.

Neuron. 2012 Apr 26;74(2):211-3. doi: 10.1016/j.neuron.2012.04.003.


PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.

Wang X, Winter D, Ashrafi G, Schlehe J, Wong YL, Selkoe D, Rice S, Steen J, LaVoie MJ, Schwarz TL.

Cell. 2011 Nov 11;147(4):893-906. doi: 10.1016/j.cell.2011.10.018.


Drosophila Importin-α2 is involved in synapse, axon and muscle development.

Mosca TJ, Schwarz TL.

PLoS One. 2010 Dec 6;5(12):e15223. doi: 10.1371/journal.pone.0015223.


Sec5, a member of the exocyst complex, mediates Drosophila embryo cellularization.

Murthy M, Teodoro RO, Miller TP, Schwarz TL.

Development. 2010 Aug;137(16):2773-83. doi: 10.1242/dev.048330. Epub 2010 Jul 14.


The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development.

Mosca TJ, Schwarz TL.

Nat Neurosci. 2010 Aug;13(8):935-43. doi: 10.1038/nn.2593. Epub 2010 Jul 4.


Are presynaptic proteins predisposed to self-assemble?

Goldstein AY, Schwarz TL.

Neuron. 2010 Jun 10;66(5):624-7. doi: 10.1016/j.neuron.2010.05.021.


Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction.

Higashi-Kovtun ME, Mosca TJ, Dickman DK, Meinertzhagen IA, Schwarz TL.

J Neurosci. 2010 Apr 14;30(15):5253-68. doi: 10.1523/JNEUROSCI.3739-09.2010.


Rab3 dynamically controls protein composition at active zones.

Graf ER, Daniels RW, Burgess RW, Schwarz TL, DiAntonio A.

Neuron. 2009 Dec 10;64(5):663-77. doi: 10.1016/j.neuron.2009.11.002.


Presynaptic alpha2delta-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions.

Kurshan PT, Oztan A, Schwarz TL.

Nat Neurosci. 2009 Nov;12(11):1415-23. doi: 10.1038/nn.2417. Epub 2009 Oct 11.


Imaging axonal transport of mitochondria.

Wang X, Schwarz TL.

Methods Enzymol. 2009;457:319-33. doi: 10.1016/S0076-6879(09)05018-6.


The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility.

Wang X, Schwarz TL.

Cell. 2009 Jan 9;136(1):163-74. doi: 10.1016/j.cell.2008.11.046.


Axonal transport and the delivery of pre-synaptic components.

Goldstein AY, Wang X, Schwarz TL.

Curr Opin Neurobiol. 2008 Oct;18(5):495-503. doi: 10.1016/j.conb.2008.10.003. Epub 2008 Oct 27. Review.

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