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Items: 1 to 20 of 191


Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.

George NM, Boerner BP, Mir SU, Guinn Z, Sarvetnick NE.

Mol Endocrinol. 2015 Nov;29(11):1594-607. doi: 10.1210/me.2014-1375. Epub 2015 Sep 17.


WS6 induces both alpha and beta cell proliferation without affecting differentiation or viability.

Boerner BP, George NM, Mir SU, Sarvetnick NE.

Endocr J. 2015;62(4):379-86. doi: 10.1507/endocrj.EJ14-0449. Epub 2015 Mar 11.


Altered CD161 bright CD8+ mucosal associated invariant T (MAIT)-like cell dynamics and increased differentiation states among juvenile type 1 diabetics.

Harms RZ, Lorenzo KM, Corley KP, Cabrera MS, Sarvetnick NE.

PLoS One. 2015 Jan 27;10(1):e0117335. doi: 10.1371/journal.pone.0117335. eCollection 2015.


Increased expression of IL-18 in the serum and islets of type 1 diabetics.

Harms RZ, Yarde DN, Guinn Z, Lorenzo-Arteaga KM, Corley KP, Cabrera MS, Sarvetnick NE.

Mol Immunol. 2015 Apr;64(2):306-12. doi: 10.1016/j.molimm.2014.12.012. Epub 2015 Jan 7.


Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death.

Mir SU, George NM, Zahoor L, Harms R, Guinn Z, Sarvetnick NE.

J Biol Chem. 2015 Mar 6;290(10):6071-85. doi: 10.1074/jbc.M114.605345. Epub 2014 Dec 29.


CD28⁻ CD8⁺ T cells are significantly reduced and correlate with disease duration in juveniles with type 1 diabetes.

Yarde DN, Lorenzo-Arteaga K, Corley KP, Cabrera M, Sarvetnick NE.

Hum Immunol. 2014 Oct;75(10):1069-74. doi: 10.1016/j.humimm.2014.09.007. Epub 2014 Sep 19.


TLR signaling controls lethal encephalitis in WNV-infected brain.

Sabouri AH, Marcondes MC, Flynn C, Berger M, Xiao N, Fox HS, Sarvetnick NE.

Brain Res. 2014 Jul 29;1574:84-95. doi: 10.1016/j.brainres.2014.05.049. Epub 2014 Jun 11.


TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability.

Boerner BP, George NM, Targy NM, Sarvetnick NE.

Endocrinology. 2013 Nov;154(11):4099-112. doi: 10.1210/en.2013-1197. Epub 2013 Aug 22.


Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.

Lao VV, Welcsh P, Luo Y, Carter KT, Dzieciatkowski S, Dintzis S, Meza J, Sarvetnick NE, Monnat RJ Jr, Loeb LA, Grady WM.

Transl Oncol. 2013 Aug 1;6(4):458-69. Print 2013 Aug.


Methamphetamine administration targets multiple immune subsets and induces phenotypic alterations suggestive of immunosuppression.

Harms R, Morsey B, Boyer CW, Fox HS, Sarvetnick N.

PLoS One. 2012;7(12):e49897. doi: 10.1371/journal.pone.0049897. Epub 2012 Dec 5.


Hippo signaling regulates pancreas development through inactivation of Yap.

George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE.

Mol Cell Biol. 2012 Dec;32(24):5116-28. doi: 10.1128/MCB.01034-12. Epub 2012 Oct 15.


Type 1 diabetes: role of intestinal microbiome in humans and mice.

Boerner BP, Sarvetnick NE.

Ann N Y Acad Sci. 2011 Dec;1243:103-18. doi: 10.1111/j.1749-6632.2011.06340.x. Review.


Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.

Liu SM, Lee DH, Sullivan JM, Chung D, Jäger A, Shum BO, Sarvetnick NE, Anderson AC, Kuchroo VK.

J Clin Invest. 2011 Nov;121(11):4303-10. doi: 10.1172/JCI46187. Epub 2011 Oct 24.


IL-18 is required for self-reactive T cell expansion in NOD mice.

Marleau AM, Sarvetnick NE.

J Autoimmun. 2011 May;36(3-4):263-77. doi: 10.1016/j.jaut.2011.02.005. Epub 2011 Mar 16.


The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditions.

King C, Sarvetnick N.

PLoS One. 2011 Feb 25;6(2):e17049. doi: 10.1371/journal.pone.0017049.


Beta-cell specific expression of suppressor of cytokine signaling-1 (SOCS-1) delays islet allograft rejection by down-regulating Interferon Regulatory Factor-1 (IRF-1) signaling.

Solomon M, Flodström-Tullberg M, Sarvetnick N.

Transpl Immunol. 2011 Apr 15;24(3):181-8. doi: 10.1016/j.trim.2010.11.007. Epub 2010 Dec 1.


Epithelial progenitor 1, a novel factor associated with epithelial cell growth and differentiation.

Kritzik MR, Lago CU, Kayali AG, Arnaud-Dabernat S, Liu G, Zhang YQ, Hua H, Fox HS, Sarvetnick NE.

Endocrine. 2010 Apr;37(2):312-21. doi: 10.1007/s12020-009-9297-5. Epub 2010 Jan 9.


CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse.

Solomon M, Balasa B, Sarvetnick N.

Autoimmunity. 2010 Mar;43(2):156-63. doi: 10.3109/08916930903246464.


Lymphocyte proliferation in immune-mediated diseases.

Datta S, Sarvetnick N.

Trends Immunol. 2009 Sep;30(9):430-8. doi: 10.1016/ Epub 2009 Aug 19. Review.


Upregulation of activin signaling in experimental colitis.

Zhang YQ, Resta S, Jung B, Barrett KE, Sarvetnick N.

Am J Physiol Gastrointest Liver Physiol. 2009 Oct;297(4):G768-80. doi: 10.1152/ajpgi.90631.2008. Epub 2009 Jul 30.

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