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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1976 2
1977 3
1978 1
1979 1
1983 2
1985 3
1986 3
1988 3
1989 2
1990 1
1991 1
1992 2
1993 5
1994 4
1995 2
1996 5
1997 3
1998 6
1999 6
2000 9
2001 15
2002 6
2003 24
2004 18
2005 16
2006 16
2007 24
2008 23
2009 32
2010 30
2011 45
2012 44
2013 40
2014 49
2015 59
2016 63
2017 79
2018 82
2019 75
2020 86
2021 104
2022 140
2023 136
2024 68

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Search Results

1,194 results

Results by year

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Page 1
Chronic kidney disease and the gut microbiome.
Hobby GP, Karaduta O, Dusio GF, Singh M, Zybailov BL, Arthur JM. Hobby GP, et al. Am J Physiol Renal Physiol. 2019 Jun 1;316(6):F1211-F1217. doi: 10.1152/ajprenal.00298.2018. Epub 2019 Mar 13. Am J Physiol Renal Physiol. 2019. PMID: 30864840 Free PMC article. Review.
Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption.
Zarkada G, Chen X, Zhou X, Lange M, Zeng L, Lv W, Zhang X, Li Y, Zhou W, Liu K, Chen D, Ricard N, Liao J, Kim YB, Benedito R, Claesson-Welsh L, Alitalo K, Simons M, Ju R, Li X, Eichmann A, Zhang F. Zarkada G, et al. Circ Res. 2023 Aug 4;133(4):333-349. doi: 10.1161/CIRCRESAHA.123.322607. Epub 2023 Jul 18. Circ Res. 2023. PMID: 37462027 Free article.
RESULTS: By studying the permeability of intestinal lacteal capillaries to lipoprotein particles known as chylomicrons, we show that ROCK (Rho-associated kinase)-dependent cytoskeletal contractility is a fundamental mechanism of LEC permeability regulation. W …
RESULTS: By studying the permeability of intestinal lacteal capillaries to lipoprotein particles known as chylomicrons, we show that …
Rho-Associated Coiled-Coil Kinase (ROCK) in Molecular Regulation of Angiogenesis.
Liu J, Wada Y, Katsura M, Tozawa H, Erwin N, Kapron CM, Bao G, Liu J. Liu J, et al. Theranostics. 2018 Nov 26;8(21):6053-6069. doi: 10.7150/thno.30305. eCollection 2018. Theranostics. 2018. PMID: 30613282 Free PMC article. Review.
In this review, we summarize recent advances in understanding the role of ROCK signaling in regulating the permeability, migration, proliferation and tubulogenesis of endothelial cells (ECs), as well as its functions in non-ECs which constitute the pro-angiogenic mi …
In this review, we summarize recent advances in understanding the role of ROCK signaling in regulating the permeability, migra …
Paleo-Rock-Hosted Life on Earth and the Search on Mars: A Review and Strategy for Exploration.
Onstott TC, Ehlmann BL, Sapers H, Coleman M, Ivarsson M, Marlow JJ, Neubeck A, Niles P. Onstott TC, et al. Astrobiology. 2019 Oct;19(10):1230-1262. doi: 10.1089/ast.2018.1960. Epub 2019 Jun 25. Astrobiology. 2019. PMID: 31237436 Free PMC article. Review.
These findings suggest that rock-hosted life would have been more likely to emerge and be preserved in a martian context. ...We expect an emphasis on rock-hosted life and this scale-dependent strategy to be crucial in the search for life on Mars....
These findings suggest that rock-hosted life would have been more likely to emerge and be preserved in a martian context. ...We expec …
Impact of the clinical use of ROCK inhibitor on the pathogenesis and treatment of glaucoma.
Honjo M, Tanihara H. Honjo M, et al. Jpn J Ophthalmol. 2018 Mar;62(2):109-126. doi: 10.1007/s10384-018-0566-9. Epub 2018 Feb 14. Jpn J Ophthalmol. 2018. PMID: 29445943 Review.
Previous studies, including our own, found that ROCK inhibitor lowers intraocular pressure (IOP) via a direct effect on the conventional AH outflow pathway, by regulation of contractile properties, fibrotic activity, and permeability of the trabecular meshwork (TM) …
Previous studies, including our own, found that ROCK inhibitor lowers intraocular pressure (IOP) via a direct effect on the conventio …
RhoA/ROCK inhibition attenuates endothelin-1-induced glomerulopathy in the rats.
Saleh MA, Shaaban AA, Talaat IM, Elmougy A, Adra SF, Ahmad F, Qaisar R, Elmoselhi AB, Abu-Gharbieh E, El-Huneidi W, Eladl MA, Shehatou G, Kafl HE. Saleh MA, et al. Life Sci. 2023 Jun 15;323:121687. doi: 10.1016/j.lfs.2023.121687. Epub 2023 Apr 6. Life Sci. 2023. PMID: 37030613
Y-27632 significantly reduced the elevation of P(alb) and albuminuria. The activities of both RhoA and ROCK-1/2 were increased by ET-1 infusion. Selective ET(B) receptor antagonism had no effect on the elevated activity of both RhoA and ROCK-1/2 enzymes. ...These ef …
Y-27632 significantly reduced the elevation of P(alb) and albuminuria. The activities of both RhoA and ROCK-1/2 were increased by ET- …
[Research progress of Rho/ROCK signal pathway].
Han JY, Yi Y, Liang AH, Zhang YS, Li CY, Wang LM, Pan C, Zhao Y. Han JY, et al. Yao Xue Xue Bao. 2016 Jun;51(6):853-9. Yao Xue Xue Bao. 2016. PMID: 29878737 Review. Chinese.
Rho/ROCK signal pathway induces cytoskeletal reorganization, cell migration and stress fiber formation, affects endothelial permeability, tissue constriction and growth, involves in diabetic nephropathy, eye disease, cancer, heart disease, nerve injury disease, hype …
Rho/ROCK signal pathway induces cytoskeletal reorganization, cell migration and stress fiber formation, affects endothelial permea …
MLCK and ROCK mutualism in endothelial barrier dysfunction.
Kazakova OA, Khapchaev AY, Shirinsky VP. Kazakova OA, et al. Biochimie. 2020 Jan;168:83-91. doi: 10.1016/j.biochi.2019.10.010. Epub 2019 Oct 24. Biochimie. 2020. PMID: 31668993
However, MLCK relies on the ROCK assistance that attenuates MLCP activity. On the other hand, MLCK supplies P-RLC myosin as an intermediate substrate to ROCK thus adding to a faster accumulation of di-(Thr18/Ser19)phosphorylated RLC (PP-RLC) by the latter kinase. .. …
However, MLCK relies on the ROCK assistance that attenuates MLCP activity. On the other hand, MLCK supplies P-RLC myosin as an interm …
Rho/Rho-associated kinase pathway in glaucoma (Review).
Wang J, Liu X, Zhong Y. Wang J, et al. Int J Oncol. 2013 Nov;43(5):1357-67. doi: 10.3892/ijo.2013.2100. Epub 2013 Sep 16. Int J Oncol. 2013. PMID: 24042317 Review.
The Rho/ROCK pathway plays important roles in the modulation of the cytoskeletal integrity of cells, the synthesis of extracellular matrix components in the aqueous humor outflow tissue and the permeability of Schlemm's canal endothelial cells. ...Furthermore, the R …
The Rho/ROCK pathway plays important roles in the modulation of the cytoskeletal integrity of cells, the synthesis of extracellular m …
1,194 results