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Diet-Induced Changes in n-3- and n-6-Derived Endocannabinoids and Reductions in Headache Pain and Psychological Distress.

Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, Faurot KR, MacIntosh BA, Majchrzak-Hong SF, Gross JR, Courville AB, Davis JM, Hibbeln JR.

J Pain. 2015 Aug;16(8):707-16. doi: 10.1016/j.jpain.2015.04.007. Epub 2015 May 7.


Targeted alterations in dietary n-3 and n-6 fatty acids improve life functioning and reduce psychological distress among patients with chronic headache: a secondary analysis of a randomized trial.

Ramsden CE, Faurot KR, Zamora D, Palsson OS, MacIntosh BA, Gaylord S, Taha AY, Rapoport SI, Hibbeln JR, Davis JM, Mann JD.

Pain. 2015 Apr;156(4):587-96. doi: 10.1097/01.j.pain.0000460348.84965.47.


The effect of modifying dietary LA and ALA intakes on omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) status in human adults: a systematic review and commentary.

Wood KE, Mantzioris E, Gibson RA, Ramsden CE, Muhlhausler BS.

Prostaglandins Leukot Essent Fatty Acids. 2015 Apr;95:47-55. doi: 10.1016/j.plefa.2015.01.001. Epub 2015 Jan 19.


Transient receptor potential vanilloid 1 gene deficiency ameliorates hepatic injury in a mouse model of chronic binge alcohol-induced alcoholic liver disease.

Liu H, Beier JI, Arteel GE, Ramsden CE, Feldstein AE, McClain CJ, Kirpich IA.

Am J Pathol. 2015 Jan;185(1):43-54. doi: 10.1016/j.ajpath.2014.09.007. Epub 2014 Oct 31.


Dietary omega-6 fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools.

Taha AY, Cheon Y, Faurot KF, Macintosh B, Majchrzak-Hong SF, Mann JD, Hibbeln JR, Ringel A, Ramsden CE.

Prostaglandins Leukot Essent Fatty Acids. 2014 May;90(5):151-7. doi: 10.1016/j.plefa.2014.02.003. Epub 2014 Feb 24.


A low omega-6 polyunsaturated fatty acid (n-6 PUFA) diet increases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans.

Wood KE, Lau A, Mantzioris E, Gibson RA, Ramsden CE, Muhlhausler BS.

Prostaglandins Leukot Essent Fatty Acids. 2014 Apr;90(4):133-8. doi: 10.1016/j.plefa.2013.12.010. Epub 2014 Jan 8.


Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.

Ramsden CE, Faurot KR, Zamora D, Suchindran CM, Macintosh BA, Gaylord S, Ringel A, Hibbeln JR, Feldstein AE, Mori TA, Barden A, Lynch C, Coble R, Mas E, Palsson O, Barrow DA, Mann JD.

Pain. 2013 Nov;154(11):2441-51. doi: 10.1016/j.pain.2013.07.028. Epub 2013 Jul 22.


Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis.

Ramsden CE, Zamora D, Leelarthaepin B, Majchrzak-Hong SF, Faurot KR, Suchindran CM, Ringel A, Davis JM, Hibbeln JR.

BMJ. 2013 Feb 4;346:e8707. doi: 10.1136/bmj.e8707. Erratum in: BMJ. 2013;346:f903.


Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research.

MacIntosh BA, Ramsden CE, Faurot KR, Zamora D, Mangan M, Hibbeln JR, Mann JD.

Br J Nutr. 2013 Aug 28;110(3):559-68. doi: 10.1017/S0007114512005181. Epub 2013 Jan 18.


Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry.

Yuan ZX, Rapoport SI, Soldin SJ, Remaley AT, Taha AY, Kellom M, Gu J, Sampson M, Ramsden CE.

Biomed Chromatogr. 2013 Apr;27(4):422-32. doi: 10.1002/bmc.2809. Epub 2012 Oct 5.


Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans.

Ramsden CE, Ringel A, Feldstein AE, Taha AY, MacIntosh BA, Hibbeln JR, Majchrzak-Hong SF, Faurot KR, Rapoport SI, Cheon Y, Chung YM, Berk M, Mann JD.

Prostaglandins Leukot Essent Fatty Acids. 2012 Oct-Nov;87(4-5):135-41. doi: 10.1016/j.plefa.2012.08.004. Epub 2012 Sep 5.


Fatty acids in cardiovascular health and disease: a comprehensive update.

Baum SJ, Kris-Etherton PM, Willett WC, Lichtenstein AH, Rudel LL, Maki KC, Whelan J, Ramsden CE, Block RC.

J Clin Lipidol. 2012 May-Jun;6(3):216-34. doi: 10.1016/j.jacl.2012.04.077. Epub 2012 Apr 13. Review.


All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts.

Ramsden CE, Hibbeln JR, Majchrzak-Hong SF.

World Rev Nutr Diet. 2011;102:30-43. doi: 10.1159/000327789. Epub 2011 Aug 5. No abstract available.


Don't disregard the essential distinction between PUFA species.

Ramsden CE, Hibbeln JR, Majchrzak-Hong SF, Davis JM.

Br J Nutr. 2011 Sep;106(6):953-7. Epub 2011 Jun 17. No abstract available.


Low omega-6 vs. low omega-6 plus high omega-3 dietary intervention for chronic daily headache: protocol for a randomized clinical trial.

Ramsden CE, Mann JD, Faurot KR, Lynch C, Imam ST, MacIntosh BA, Hibbeln JR, Loewke J, Smith S, Coble R, Suchindran C, Gaylord SA.

Trials. 2011 Apr 15;12:97. doi: 10.1186/1745-6215-12-97.


Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century.

Blasbalg TL, Hibbeln JR, Ramsden CE, Majchrzak SF, Rawlings RR.

Am J Clin Nutr. 2011 May;93(5):950-62. doi: 10.3945/ajcn.110.006643. Epub 2011 Mar 2.


n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials.

Ramsden CE, Hibbeln JR, Majchrzak SF, Davis JM.

Br J Nutr. 2010 Dec;104(11):1586-600. doi: 10.1017/S0007114510004010.


Dietary fat quality and coronary heart disease prevention: a unified theory based on evolutionary, historical, global, and modern perspectives.

Ramsden CE, Faurot KR, Carrera-Bastos P, Cordain L, De Lorgeril M, Sperling LS.

Curr Treat Options Cardiovasc Med. 2009 Aug;11(4):289-301.


Letter to the Editor re: Linoleic acid and coronary heart disease. Prostaglandins Leukot. Essent. Fatty Acids (2008), by W.S. Harris.

Ramsden CE, Hibbeln JR, Lands WE.

Prostaglandins Leukot Essent Fatty Acids. 2009 Jan;80(1):77; author reply 77-8. doi: 10.1016/j.plefa.2008.12.002. Epub 2009 Jan 14. No abstract available.


Pudendal nerve entrapment as source of intractable perineal pain.

Ramsden CE, McDaniel MC, Harmon RL, Renney KM, Faure A.

Am J Phys Med Rehabil. 2003 Jun;82(6):479-84. Review.

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