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Year Number of Results
1998 1
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2007 13
2008 12
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2012 7
2013 11
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178 results

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Page 1
Role of epigallocatechin gallate (EGCG) in the treatment of breast and prostate cancer.
Stuart EC, Scandlyn MJ, Rosengren RJ. Stuart EC, et al. Life Sci. 2006 Nov 17;79(25):2329-36. doi: 10.1016/j.lfs.2006.07.036. Epub 2006 Aug 5. Life Sci. 2006. PMID: 16945390 Review.
Epidemiological data have suggested that EGCG may provide protective effects against hormone related cancers, namely breast or prostate cancer. ...This review will highlight the important in vitro mechanistic actions elicited by EGCG in various breast …
Epidemiological data have suggested that EGCG may provide protective effects against hormone related cancers, namely breast or pro …
Increased expression of androgen receptor and PSA genes in LNCaP (prostate cancer) cell line due to high concentrations of EGCG, an active ingredient in green tea.
Bakhshandeh N, Mohammadi M, Mohammadi P, Nazari E, Damchi M, Khodabandelu S, Mokhtari H. Bakhshandeh N, et al. Horm Mol Biol Clin Investig. 2022 Dec 30;44(2):181-186. doi: 10.1515/hmbci-2022-0054. eCollection 2023 Jun 1. Horm Mol Biol Clin Investig. 2022. PMID: 36578191
Previous studies have shown that EGCG at low concentrations reduces the expression of AR and prostate-specific antigen (PSA) in the LNCaP cell line of prostate cancer. In this study, the effect of higher EGCG concentrations on AR and PSA express …
Previous studies have shown that EGCG at low concentrations reduces the expression of AR and prostate-specific antigen (PSA) i …
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism.
Modernelli A, Naponelli V, Giovanna Troglio M, Bonacini M, Ramazzina I, Bettuzzi S, Rizzi F. Modernelli A, et al. Sci Rep. 2015 Oct 16;5:15270. doi: 10.1038/srep15270. Sci Rep. 2015. PMID: 26471237 Free PMC article.
We investigated whether combined delivery of a proteasome inhibitor with EGCG enhances prostate cancer cell death through increased induction of ER stress. ...Conversely, the MG132 dose-response curve was unaffected by co-administration of EGCG. Moreov …
We investigated whether combined delivery of a proteasome inhibitor with EGCG enhances prostate cancer cell death throu …
EGCG/gelatin-doxorubicin gold nanoparticles enhance therapeutic efficacy of doxorubicin for prostate cancer treatment.
Tsai LC, Hsieh HY, Lu KY, Wang SY, Mi FL. Tsai LC, et al. Nanomedicine (Lond). 2016 Jan;11(1):9-30. doi: 10.2217/nnm.15.183. Epub 2015 Dec 11. Nanomedicine (Lond). 2016. PMID: 26654241
AIM: Development of epigallocatechin gallate (EGCG) and gelatin-doxorubicin conjugate (GLT-DOX)-coated gold nanoparticles (DOX-GLT/EGCG AuNPs) for fluorescence imaging and inhibition of prostate cancer cell growth. MATERIALS & METHODS: AuNPs altern …
AIM: Development of epigallocatechin gallate (EGCG) and gelatin-doxorubicin conjugate (GLT-DOX)-coated gold nanoparticles (DOX-GLT/ …
Reports of Plant-Derived Nanoparticles for Prostate Cancer Therapy.
Elbagory AM, Hull R, Meyer M, Dlamini Z. Elbagory AM, et al. Plants (Basel). 2023 May 3;12(9):1870. doi: 10.3390/plants12091870. Plants (Basel). 2023. PMID: 37176928 Free PMC article. Review.
Plants have demonstrated potential in providing various types of phytomedicines with chemopreventive properties that can combat prostate cancer. However, despite their promising in vitro activity, the incorporation of these phytochemicals into the market as anticanc …
Plants have demonstrated potential in providing various types of phytomedicines with chemopreventive properties that can combat prostate …
Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer.
Siddiqui IA, Asim M, Hafeez BB, Adhami VM, Tarapore RS, Mukhtar H. Siddiqui IA, et al. FASEB J. 2011 Apr;25(4):1198-207. doi: 10.1096/fj.10-167924. Epub 2010 Dec 21. FASEB J. 2011. PMID: 21177307 Free PMC article.
Androgen deprivation therapy is the major treatment for advanced prostate cancer (PCa). However, it is a temporary remission, and the patients almost inevitably develop hormone refractory prostate cancer (HRPC). ...As the physiological consequence of A …
Androgen deprivation therapy is the major treatment for advanced prostate cancer (PCa). However, it is a temporary remission, …
EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity.
Lee YH, Kwak J, Choi HK, Choi KC, Kim S, Lee J, Jun W, Park HJ, Yoon HG. Lee YH, et al. Int J Mol Med. 2012 Jul;30(1):69-74. doi: 10.3892/ijmm.2012.966. Epub 2012 Apr 10. Int J Mol Med. 2012. PMID: 22505206
Manipulating acetylation status of key gene targets is likely to be crucial for effective cancer therapy. In this study, we utilized green tea catechins, epicatechin (EC), epigallocatechin (EGC) and epigallocatechin-3-gallate (EGCG) to examine the regulation of andr …
Manipulating acetylation status of key gene targets is likely to be crucial for effective cancer therapy. In this study, we utilized …
Epigenetic Changes Induced by Green Tea Catechins a re Associated with Prostate Cancer.
Giudice A, Montella M, Boccellino M, Crispo A, D'Arena G, Bimonte S, Facchini G, Ciliberto G, Botti G, Quagliuolo L, Caraglia M, Capunzo M. Giudice A, et al. Curr Mol Med. 2017;17(6):405-420. doi: 10.2174/1566524018666171219101937. Curr Mol Med. 2017. PMID: 29256350 Review.
Prostate cancer is one of the most difficult cancers to treat especially when it becomes hormone resistant such as castrate resistant prostate cancer (CRPC) and subsequent metastatic CRPC. ...This review will summarize the key results from recent studi …
Prostate cancer is one of the most difficult cancers to treat especially when it becomes hormone resistant such as castrate re …
Green tea polyphenol epigallocatechin-3-gallate (EGCG) as adjuvant in cancer therapy.
Lecumberri E, Dupertuis YM, Miralbell R, Pichard C. Lecumberri E, et al. Clin Nutr. 2013 Dec;32(6):894-903. doi: 10.1016/j.clnu.2013.03.008. Epub 2013 Mar 15. Clin Nutr. 2013. PMID: 23582951 Review.
BACKGROUND & AIMS: Green tea catechins, especially epigallocatechin-3-gallate (EGCG), have been associated with cancer prevention and treatment. ...Further research, especially at the clinical level, is needed to ascertain the potential role of EGCG as ad …
BACKGROUND & AIMS: Green tea catechins, especially epigallocatechin-3-gallate (EGCG), have been associated with cancer pre …
The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition.
Tang SN, Singh C, Nall D, Meeker D, Shankar S, Srivastava RK. Tang SN, et al. J Mol Signal. 2010 Aug 18;5:14. doi: 10.1186/1750-2187-5-14. J Mol Signal. 2010. PMID: 20718984 Free PMC article.
RESULTS: Our data indicate that human prostate cancer cell lines contain a small population of CD44+CD133+ cancer stem cells and their self-renewal capacity is inhibited by EGCG. ...CONCLUSION: Since carcinogenesis is a complex process, combination of …
RESULTS: Our data indicate that human prostate cancer cell lines contain a small population of CD44+CD133+ cancer stem …
178 results