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Page 1
Synthesis and Preliminary Biological Evaluations of Fluorescent or (149)Promethium Labeled Trastuzumab-Polyethylenimine.
Fitzsimmons J, Nayak T, Cutler C, Atcher R. Fitzsimmons J, et al. Biomedicines. 2015 Dec 30;4(1):1. doi: 10.3390/biomedicines4010001. Biomedicines. 2015. PMID: 28536369 Free PMC article.
In vitro uptake, internalization and/or the binding affinity to the Her2/neu expressing human breast adenocarcinoma SKBr3 cells was investigated with the labeled compounds. RESULTS: Fluorescent-labeled Trastuzumab-PEI was internalized more into cells at 2 and 18 h t …
In vitro uptake, internalization and/or the binding affinity to the Her2/neu expressing human breast adenocarcinoma SKBr3 cells was i …
Toxicological and cytophysiological aspects of lanthanides action.
Pałasz A, Czekaj P. Pałasz A, et al. Acta Biochim Pol. 2000;47(4):1107-14. Acta Biochim Pol. 2000. PMID: 11996100 Free article. Review.
In the liver, gadolinium selectively inhibits secretion by Kupffer cells and it decreases cytochrome P450 activity in hepatocytes, thereby protecting liver cells against toxic products of xenobiotic biotransformation. ...Trivalent lanthanide ions, especially La3+ an …
In the liver, gadolinium selectively inhibits secretion by Kupffer cells and it decreases cytochrome P450 activity in hepatocytes, th …
Effects of lanthanum in cellular systems. A review.
Das T, Sharma A, Talukder G. Das T, et al. Biol Trace Elem Res. 1988 Dec;18:201-28. doi: 10.1007/BF02917504. Biol Trace Elem Res. 1988. PMID: 2484565 Review.
Lanthanum belongs to the group of elements known as "lanthanons," which also includes cerium, europium, promethium, and thulium. It is the most electropositive element of the rare earth group, is uniformly trivalent, and is similar in its chemical properties to the alkalin …
Lanthanum belongs to the group of elements known as "lanthanons," which also includes cerium, europium, promethium, and thulium. It i …
Pm-149 DOTA bombesin analogs for potential radiotherapy. in vivo comparison with Sm-153 and Lu-177 labeled DO3A-amide-betaAla-BBN(7-14)NH(2).
Hu F, Cutler CS, Hoffman T, Sieckman G, Volkert WA, Jurisson SS. Hu F, et al. Nucl Med Biol. 2002 May;29(4):423-30. doi: 10.1016/s0969-8051(02)00290-1. Nucl Med Biol. 2002. PMID: 12031877
Promethium-149 (149Pm) is one of only three radiolanthanides that can be prepared in no carrier added concentrations. This high specific activity radiolanthanide is thus suitable for targeting limited numbers of specific receptors found on many tumor cells. Prome …
Promethium-149 (149Pm) is one of only three radiolanthanides that can be prepared in no carrier added concentrations. This high speci …
Antibacterial, Antifungal and Nematicidal Activities of Rare Earth Ions.
Wakabayashi T, Ymamoto A, Kazaana A, Nakano Y, Nojiri Y, Kashiwazaki M. Wakabayashi T, et al. Biol Trace Elem Res. 2016 Dec;174(2):464-470. doi: 10.1007/s12011-016-0727-y. Epub 2016 May 5. Biol Trace Elem Res. 2016. PMID: 27147430
In this study, we have examined the effect of rare earth ions on the growth of bacteria, fungi and soil nematode. All rare earth ions, except radioactive promethium that we have not tested, showed antibacterial and antifungal activities comparable to that of copper ions, w …
In this study, we have examined the effect of rare earth ions on the growth of bacteria, fungi and soil nematode. All rare earth ions, excep …
The response of murine intestinal crypts to short-range promethium-147 beta irradiation: deductions concerning clonogenic cell numbers and positions.
Hendry JH, Potten CS, Ghafoor A, Moore JV, Roberts SA, Williams PC. Hendry JH, et al. Radiat Res. 1989 May;118(2):364-74. Radiat Res. 1989. PMID: 2727264
The shape of the curve was interpreted in terms of survival parameters for colony-forming cells (clonogens) derived using 137Cs gamma rays and the depth-dose curve measured for 147Pm electrons. ...A computer fitting procedure showed that the best agreement between predicte …
The shape of the curve was interpreted in terms of survival parameters for colony-forming cells (clonogens) derived using 137Cs gamma …
Nonstochastic effects of different energy beta emitters on pig skin.
Peel DM, Hopewell JW, Wells J, Charles MW. Peel DM, et al. Radiat Res. 1984 Aug;99(2):372-82. Radiat Res. 1984. PMID: 6463213
During the first 16 weeks after irradiation 90Sr produced a first reaction due to epithelial cell death followed by a second reaction attributable to damage to the dermal blood vessels. 170Tm and 147Pm produced the epithelial reaction only. ...
During the first 16 weeks after irradiation 90Sr produced a first reaction due to epithelial cell death followed by a second reaction …
Distribution of a lanthanide (147 Pm) in vascular smooth muscle.
Weiss GB, Goodman FR. Weiss GB, et al. J Pharmacol Exp Ther. 1976 Aug;198(2):366-74. J Pharmacol Exp Ther. 1976. PMID: 820850
In order to ascertain whether trivalent rare earth ions such as lanthanum (La+++) penetrate the cell membrane under physiological conditions, the extracellular and cellular distribution of promethium (147 Pm), a carrier-free rare earth radioisotope, was examined in …
In order to ascertain whether trivalent rare earth ions such as lanthanum (La+++) penetrate the cell membrane under physiological con …
[Selective accumulation of 147Pm in organism on induction of micronucleus and SCE of bone marrow cells as well as the mutagenic effect on fetal liver and spleen].
Zhu SP. Zhu SP. Zhonghua Yu Fang Yi Xue Za Zhi. 1989 May;23(3):166-9. Zhonghua Yu Fang Yi Xue Za Zhi. 1989. PMID: 2582927 Chinese.
A statistically significant elevation of SCEs was observed after 147Pm intake. The number of SCEs per cell in bone marrow cells was always higher in mice when the animals were maintained on the doses of 37 Bq/g. ...Studies indicated that maternal contamination of 14 …
A statistically significant elevation of SCEs was observed after 147Pm intake. The number of SCEs per cell in bone marrow cells …
14 results