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Page 1
Showing results for pocket
Search for porket instead (1 results)
The periodontal pocket.
Donos N. Donos N. Periodontol 2000. 2018 Feb;76(1):7-15. doi: 10.1111/prd.12203. Epub 2017 Nov 30. Periodontol 2000. 2018. PMID: 29194794 Review.
Periodontal disease is synonymous with the presence of periodontal pockets, and very often the clinical success of periodontal therapy is based on periodontal pocket depth reduction. ...These reviews aim to provide the readers with current and future perspectives on …
Periodontal disease is synonymous with the presence of periodontal pockets, and very often the clinical success of periodontal therap …
Pocket closure and residual pockets after non-surgical periodontal therapy: A systematic review and meta-analysis.
Citterio F, Gualini G, Chang M, Piccoli GM, Giraudi M, Manavella V, Baima G, Mariani GM, Romano F, Aimetti M. Citterio F, et al. J Clin Periodontol. 2022 Jan;49(1):2-14. doi: 10.1111/jcpe.13547. Epub 2021 Nov 11. J Clin Periodontol. 2022. PMID: 34517433 Free PMC article. Review.
AIM: To analyse the efficacy of non-surgical therapy (NST) in terms of pocket closure (PC) and changes in percentage and number of pockets. ...The mean number of residual PPD 5 after NST was 14.13. CONCLUSIONS: NST is able to eradicate the majority of the pockets …
AIM: To analyse the efficacy of non-surgical therapy (NST) in terms of pocket closure (PC) and changes in percentage and number of …
Protein Binding Pocket Dynamics.
Stank A, Kokh DB, Fuller JC, Wade RC. Stank A, et al. Acc Chem Res. 2016 May 17;49(5):809-15. doi: 10.1021/acs.accounts.5b00516. Epub 2016 Apr 25. Acc Chem Res. 2016. PMID: 27110726 Free article. Review.
For example, channels and tunnels can exist permanently or transiently to transport compounds to and from a binding site. The influence of protein flexibility on binding pockets can vary from small changes to an already existent pocket to the formation of a complete …
For example, channels and tunnels can exist permanently or transiently to transport compounds to and from a binding site. The influence of p …
Accelerating Cryptic Pocket Discovery Using AlphaFold.
Meller A, Bhakat S, Solieva S, Bowman GR. Meller A, et al. J Chem Theory Comput. 2023 Jul 25;19(14):4355-4363. doi: 10.1021/acs.jctc.2c01189. Epub 2023 Mar 22. J Chem Theory Comput. 2023. PMID: 36948209 Free PMC article.
Here, we investigate whether AlphaFold can be used to accelerate cryptic pocket discovery either by generating structures with open pockets directly or generating structures with partially open pockets that can be used as starting points for simulations. ...T …
Here, we investigate whether AlphaFold can be used to accelerate cryptic pocket discovery either by generating structures with open …
Surgical treatment of the residual periodontal pocket.
Graziani F, Karapetsa D, Mardas N, Leow N, Donos N. Graziani F, et al. Periodontol 2000. 2018 Feb;76(1):150-163. doi: 10.1111/prd.12156. Epub 2017 Nov 29. Periodontol 2000. 2018. PMID: 29193404 Review.
However, despite completion of nonsurgical treatment, a number of periodontal pockets, defined as 'residual', often remain. The presence of residual pockets may jeopardize tooth survival and be a risk factor of further disease progression, and ultimately tooth loss. …
However, despite completion of nonsurgical treatment, a number of periodontal pockets, defined as 'residual', often remain. The prese …
Pocket-based drug design: exploring pocket space.
Zheng X, Gan L, Wang E, Wang J. Zheng X, et al. AAPS J. 2013 Jan;15(1):228-41. doi: 10.1208/s12248-012-9426-6. Epub 2012 Nov 22. AAPS J. 2013. PMID: 23180158 Free PMC article. Review.
Herein, some recent progresses and developments of the computational analysis of pockets have been covered. Also, the pockets at the protein-protein interfaces (PPI) have been considered to further explore the pocket space for drug discovery. We have presente …
Herein, some recent progresses and developments of the computational analysis of pockets have been covered. Also, the pockets …
SiteFerret: Beyond Simple Pocket Identification in Proteins.
Gagliardi L, Rocchia W. Gagliardi L, et al. J Chem Theory Comput. 2023 Aug 8;19(15):5242-5259. doi: 10.1021/acs.jctc.2c01306. Epub 2023 Jul 20. J Chem Theory Comput. 2023. PMID: 37470784 Free PMC article.
The final ranking of putative pockets is based on the Isolation Forest method, an unsupervised learning approach originally developed for anomaly detection. ...The method also provides a segmentation of pockets into smaller subpockets. We prove that subpockets are a …
The final ranking of putative pockets is based on the Isolation Forest method, an unsupervised learning approach originally developed …
Opening of a cryptic pocket in beta-lactamase increases penicillinase activity.
Knoverek CR, Mallimadugula UL, Singh S, Rennella E, Frederick TE, Yuwen T, Raavicharla S, Kay LE, Bowman GR. Knoverek CR, et al. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2106473118. doi: 10.1073/pnas.2106473118. Proc Natl Acad Sci U S A. 2021. PMID: 34799442 Free PMC article.
Using thiol-labeling assays to probe omega-loop pocket dynamics and kinetic assays to probe activity, we find that while this pocket is not completely conserved across beta-lactamase homologs, those with the omega-loop pocket have a higher activity against th …
Using thiol-labeling assays to probe omega-loop pocket dynamics and kinetic assays to probe activity, we find that while this pock …
Tympanic membrane. Retraction pocket.
Ars B. Ars B. Acta Otorhinolaryngol Belg. 1995;49(2):163-71. Acta Otorhinolaryngol Belg. 1995. PMID: 7610909 Review.
The author attempts to analyse the pathogenesis of the retraction pocket. Middle ear pressure, behaviour of both the tympanic membrane lamina propria and the stratified squamous epithelium are considered. ...A conservative surgical treatment is suggested in cases of non-fi …
The author attempts to analyse the pathogenesis of the retraction pocket. Middle ear pressure, behaviour of both the tympanic membran …
Pocket closure after repeated subgingival instrumentation: a stress test to the EFP guideline for stage III-IV periodontitis.
Ferrarotti F, Baima G, Rendinelli M, Citterio F, Mariani GM, Mussano F, Romano F, Romandini M, Aimetti M. Ferrarotti F, et al. Clin Oral Investig. 2023 Nov;27(11):6701-6708. doi: 10.1007/s00784-023-05279-6. Epub 2023 Sep 29. Clin Oral Investig. 2023. PMID: 37773418 Free PMC article.
OBJECTIVES: To study the effects of one or two repeated subgingival instrumentations (RSI) in achieving the endpoints of therapy (EoT) in open pockets [residual probing pocket depth (PPD) 6 mm and PPD 4-5 mm with bleeding on probing (BoP)] after steps I-II of therap …
OBJECTIVES: To study the effects of one or two repeated subgingival instrumentations (RSI) in achieving the endpoints of therapy (EoT) in op …
75,874 results
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