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Showing results for podocyte
Your search for podolite retrieved no results
Podocyte injury and its consequences.
Nagata M. Nagata M. Kidney Int. 2016 Jun;89(6):1221-30. doi: 10.1016/j.kint.2016.01.012. Epub 2016 Mar 19. Kidney Int. 2016. PMID: 27165817 Free article. Review.
In addition to "sick" podocytes and their detachment, our understanding of glomerular responses following podocyte loss needs to address the pathways from podocyte injury to sclerosis. Studies have found a variety of glomerular responses to podocyte dy …
In addition to "sick" podocytes and their detachment, our understanding of glomerular responses following podocyte loss needs …
A Review of Podocyte Biology.
Garg P. Garg P. Am J Nephrol. 2018;47 Suppl 1:3-13. doi: 10.1159/000481633. Epub 2018 May 31. Am J Nephrol. 2018. PMID: 29852492 Free article. Review.
Proteinuria in nephrotic syndrome has been linked to mechanistic dysfunctions in the renal glomerulus involving the function of podocyte epithelial cells, including podocyte foot process effacement. ...The process of podocyte depletion correlates with the dev …
Proteinuria in nephrotic syndrome has been linked to mechanistic dysfunctions in the renal glomerulus involving the function of podocyte …
Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.
Fu Y, Sun Y, Wang M, Hou Y, Huang W, Zhou D, Wang Z, Yang S, Tang W, Zhen J, Li Y, Wang X, Liu M, Zhang Y, Wang B, Liu G, Yu X, Sun J, Zhang C, Yi F. Fu Y, et al. Cell Metab. 2020 Dec 1;32(6):1052-1062.e8. doi: 10.1016/j.cmet.2020.10.019. Epub 2020 Nov 12. Cell Metab. 2020. PMID: 33186558 Free article.
Lipid accumulation in podocytes is a major determinant of diabetic kidney disease (DKD) and identification of potential therapeutic targets by mediating podocyte lipid metabolism has clinical importance. This study was to elucidate the role of JAML (junctional adhes …
Lipid accumulation in podocytes is a major determinant of diabetic kidney disease (DKD) and identification of potential therapeutic t …
Podocyte Sphingolipid Signaling in Nephrotic Syndrome.
Li G, Kidd J, Gehr TWB, Li PL. Li G, et al. Cell Physiol Biochem. 2021 Apr 17;55(S4):13-34. doi: 10.33594/000000356. Cell Physiol Biochem. 2021. PMID: 33861526 Free PMC article. Review.
Podocytes play a vital role in the pathogenesis of nephrotic syndrome (NS), which is clinically characterized by heavy proteinuria, hypoalbuminemia, hyperlipidemia, and peripheral edema. ...This review briefly summarizes current evidence demonstrating the regulation of sph …
Podocytes play a vital role in the pathogenesis of nephrotic syndrome (NS), which is clinically characterized by heavy proteinuria, h …
Role of Podocyte Injury in Glomerulosclerosis.
Lu CC, Wang GH, Lu J, Chen PP, Zhang Y, Hu ZB, Ma KL. Lu CC, et al. Adv Exp Med Biol. 2019;1165:195-232. doi: 10.1007/978-981-13-8871-2_10. Adv Exp Med Biol. 2019. PMID: 31399967 Free PMC article. Review.
Due to a living environment of various stresses and pathological stimuli, podocytes are prone to injuries; moreover, as a cell without proliferative potential, loss of podocytes is vital in the pathogenesis of glomerulosclerosis. ...Injury-induced changes in podo …
Due to a living environment of various stresses and pathological stimuli, podocytes are prone to injuries; moreover, as a cell withou …
Bioengineering Strategies to Develop Podocyte Culture Systems.
Williams S, Charest JL, Pollak MR, Subramanian B. Williams S, et al. Tissue Eng Part B Rev. 2022 Aug;28(4):938-948. doi: 10.1089/ten.TEB.2021.0154. Epub 2021 Dec 8. Tissue Eng Part B Rev. 2022. PMID: 34541902 Free PMC article. Review.
With the advent of bioengineered models, an increasingly powerful and diverse set of tools is available to develop novel podocyte culture systems. This review discusses the pertinence of various culture models of podocytes to study podocyte mechanisms in both …
With the advent of bioengineered models, an increasingly powerful and diverse set of tools is available to develop novel podocyte cul …
Gangliosides in Podocyte Biology and Disease.
Savas B, Astarita G, Aureli M, Sahali D, Ollero M. Savas B, et al. Int J Mol Sci. 2020 Dec 17;21(24):9645. doi: 10.3390/ijms21249645. Int J Mol Sci. 2020. PMID: 33348903 Free PMC article. Review.
In this review, we make a point on the relevance of gangliosides and some of their metabolic precursors, such as ceramides, in the function of podocytes, the main cellular component of the glomerular filtration barrier, as well as their implications in podocytopathies. ...
In this review, we make a point on the relevance of gangliosides and some of their metabolic precursors, such as ceramides, in the function …
The podocyte protease web: uncovering the gatekeepers of glomerular disease.
Rinschen MM, Huesgen PF, Koch RE. Rinschen MM, et al. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1812-F1816. doi: 10.1152/ajprenal.00380.2018. Epub 2018 Sep 19. Am J Physiol Renal Physiol. 2018. PMID: 30230368 Free article. Review.
Both the extracellular and intracellular proteolytic networks are perturbed in focal segmental glomerulosclerosis, as well as hypertensive and diabetic nephropathy. Accordingly, the highly intertwined podocyte protease web is an integrative part of the podocyte's …
Both the extracellular and intracellular proteolytic networks are perturbed in focal segmental glomerulosclerosis, as well as hypertensive a …
Imaging podocyte dynamics.
Moeller MJ, Holzman LB. Moeller MJ, et al. Nephron Exp Nephrol. 2006;103(2):e69-74. doi: 10.1159/000090619. Epub 2006 Mar 10. Nephron Exp Nephrol. 2006. PMID: 16543767 Review.
Cytoskeletal dynamics play important roles during normal podocyte development, in maintenance of the healthy glomerular filter, and in glomerular pathology. ...This review will summarize recent progress in understanding cytoskeletal dynamics in the podocyte and will …
Cytoskeletal dynamics play important roles during normal podocyte development, in maintenance of the healthy glomerular filter, and i …
Quantifying podocyte depletion: theoretical and practical considerations.
Puelles VG, Bertram JF, Moeller MJ. Puelles VG, et al. Cell Tissue Res. 2017 Jul;369(1):229-236. doi: 10.1007/s00441-017-2630-z. Epub 2017 May 30. Cell Tissue Res. 2017. PMID: 28560693 Review.
Podocyte depletion is a central event in the pathogenesis of many glomerular diseases. For this reason, methods to quantify podocyte depletion have become increasingly important. Here, we review currently available methods for quantifying podocyte depletion, …
Podocyte depletion is a central event in the pathogenesis of many glomerular diseases. For this reason, methods to quantify podocy …
11,140 results
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