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Year Number of Results
1960 2
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1964 1
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1966 2
1968 1
1970 1
1971 1
1972 1
1976 1
1977 1
1978 1
1979 1
1981 3
1982 1
1983 4
1984 1
1985 1
1986 1
1987 5
1988 3
1989 2
1991 1
1993 1
1994 1
1996 2
1997 2
1998 1
2000 4
2001 1
2003 1
2004 1
2005 2
2006 2
2011 2
2012 1
2013 1
2015 3
2016 1
2017 7
2018 11
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2020 5
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2023 3
2024 2

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110 results

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Page 1
Chlorthalidone.
[No authors listed] [No authors listed] 2021 Jan 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Jan 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000622 Free Books & Documents. Review.
1-Isoindolinone scaffold-based natural products with a promising diverse bioactivity.
Upadhyay SP, Thapa P, Sharma R, Sharma M. Upadhyay SP, et al. Fitoterapia. 2020 Oct;146:104722. doi: 10.1016/j.fitote.2020.104722. Epub 2020 Sep 10. Fitoterapia. 2020. PMID: 32920034 Review.
Isoindolin-1-one or 1-isoindolinone framework is referred to phthalimidines or benzo fused gamma-lactams of the corresponding gamma-amino carboxylic acids and has been of prime interest for scientists for last several decades. 1-Isoindolinone framework is found in a wide r …
Isoindolin-1-one or 1-isoindolinone framework is referred to phthalimidines or benzo fused gamma-lactams of the corresponding gamma-a …
Design, synthesis and biological assessment of N-adamantyl, substituted adamantyl and noradamantyl phthalimidines for nitrite, TNF-alpha and angiogenesis inhibitory activities.
Luo W, Tweedie D, Beedie SL, Vargesson N, Figg WD, Greig NH, Scerba MT. Luo W, et al. Bioorg Med Chem. 2018 May 1;26(8):1547-1559. doi: 10.1016/j.bmc.2018.01.032. Epub 2018 Feb 10. Bioorg Med Chem. 2018. PMID: 29472124 Free PMC article.
Phthalimidine treatment in LPS-challenged cells effected reductions in levels of secreted TNF-alpha and nitrite relative to basal amounts. ...Site-specific nitration and thioamidation provided phthalimidine 24, effecting an 88.5% drop in nitrite concurrent with only …
Phthalimidine treatment in LPS-challenged cells effected reductions in levels of secreted TNF-alpha and nitrite relative to basal amo …
Isoindolinone Synthesis via One-Pot Type Transition Metal Catalyzed C-C Bond Forming Reactions.
Savela R, Méndez-Gálvez C. Savela R, et al. Chemistry. 2021 Mar 22;27(17):5344-5378. doi: 10.1002/chem.202004375. Epub 2021 Feb 2. Chemistry. 2021. PMID: 33125790 Free PMC article. Review.
In general, the synthetic strategies can be divided into two categories: First, direct utilization of phthalimides or phthalimidines as starting materials for the synthesis of isoindolinones; and second, construction of the lactam and/or aromatic rings by different catalyt …
In general, the synthetic strategies can be divided into two categories: First, direct utilization of phthalimides or phthalimidines …
Marilines A-C: novel phthalimidines from the sponge-derived fungus Stachylidium sp.
Almeida C, Hemberger Y, Schmitt SM, Bouhired S, Natesan L, Kehraus S, Dimas K, Gütschow M, Bringmann G, König GM. Almeida C, et al. Chemistry. 2012 Jul 9;18(28):8827-34. doi: 10.1002/chem.201103278. Epub 2012 Jun 18. Chemistry. 2012. PMID: 22711513
Chemical investigation of the bioactive fungal extract led to the isolation of the novel phthalimidine derivatives marilines A(1) (1a), A(2) (1b), B (2), and C (3). ...
Chemical investigation of the bioactive fungal extract led to the isolation of the novel phthalimidine derivatives marilines A(1) (1a …
Synthesis of antifungal 2-substituted phthalimidines.
Schwan TJ, Gray JE. Schwan TJ, et al. J Pharm Sci. 1978 Jun;67(6):863-4. doi: 10.1002/jps.2600670638. J Pharm Sci. 1978. PMID: 660477
An improved synthesis of phthalimidine is reported. Two N-substituted phthalimidines were synthesized by alkylation of the parent compound, and they showed complete inhibition of Microsporum and Trichophyton species at 10-100 microgram/ml in an agar dilution test. . …
An improved synthesis of phthalimidine is reported. Two N-substituted phthalimidines were synthesized by alkylation of the par …
Traceless and Chemoselective Amine Bioconjugation via Phthalimidine Formation in Native Protein Modification.
Tung CL, Wong CT, Fung EY, Li X. Tung CL, et al. Org Lett. 2016 Jun 3;18(11):2600-3. doi: 10.1021/acs.orglett.6b00983. Epub 2016 May 18. Org Lett. 2016. PMID: 27191384
ortho-Phthalaldehyde (OPA) and its derivatives are found to react chemoselectively with amino groups on peptides and proteins rapidly and tracelessly under the physiological condition via formation of phthalimidines, which provides a novel and promising approach when perfo …
ortho-Phthalaldehyde (OPA) and its derivatives are found to react chemoselectively with amino groups on peptides and proteins rapidly and tr …
Ligands for the common allosteric site of acetylcholine M2-receptors: development and application.
Holzgrabe U, Bender W, Cid HM, Staudt M, Pick R, Pfletschinger C, Balatková E, Tränkle C, Mohr K. Holzgrabe U, et al. Pharm Acta Helv. 2000 Mar;74(2-3):149-55. doi: 10.1016/s0031-6865(99)00028-x. Pharm Acta Helv. 2000. PMID: 10812952 Review.
Thus, we synthesized and pharmacologically evaluated compounds bearing "saturated" phthalimide moieties as well as phthalimidines with substituents of systematically increasing size in position 3 or on the aromatic ring at one or both ends of the molecule. ...
Thus, we synthesized and pharmacologically evaluated compounds bearing "saturated" phthalimide moieties as well as phthalimidines wit …
110 results