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Results: 1 to 20 of 41

1.

Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets.

Sui H, Yi Y, Yao J, Liang B, Sun X, Hu S, Uc A, Nelson DJ, Ode KL, Philipson LH, Engelhardt JF, Norris AW.

PLoS One. 2014 Mar 3;9(3):e90519. doi: 10.1371/journal.pone.0090519. eCollection 2014.

PMID:
24594704
[PubMed - in process]
Free PMC Article
2.

Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin.

Park SY, Ludwig MZ, Tamarina NA, He BZ, Carl SH, Dickerson DA, Barse L, Arun B, Williams CL, Miles CM, Philipson LH, Steiner DF, Bell GI, Kreitman M.

Genetics. 2014 Feb;196(2):539-55. doi: 10.1534/genetics.113.157602. Epub 2013 Nov 26.

PMID:
24281154
[PubMed - in process]
Free PMC Article
3.

Distribution of directional change as a signature of complex dynamics.

Burov S, Tabei SM, Huynh T, Murrell MP, Philipson LH, Rice SA, Gardel ML, Scherer NF, Dinner AR.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19689-94. doi: 10.1073/pnas.1319473110. Epub 2013 Nov 18.

PMID:
24248363
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Ion channels and regulation of insulin secretion in human β-cells: a computational systems analysis.

Fridlyand LE, Jacobson DA, Philipson LH.

Islets. 2013 Jan-Feb;5(1):1-15. doi: 10.4161/isl.24166. Review.

PMID:
23624892
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Transgenic zebrafish model of the C43G human insulin gene mutation.

Eames SC, Kinkel MD, Rajan S, Prince VE, Philipson LH.

J Diabetes Investig. 2013 Mar 18;4(2):157-67. doi: 10.1111/jdi.12015. Epub 2012 Nov 5.

PMID:
24843647
[PubMed]
Free PMC Article
6.

Intracellular transport of insulin granules is a subordinated random walk.

Tabei SM, Burov S, Kim HY, Kuznetsov A, Huynh T, Jureller J, Philipson LH, Dinner AR, Scherer NF.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4911-6. doi: 10.1073/pnas.1221962110. Epub 2013 Mar 11.

PMID:
23479621
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion.

Kaihara KA, Dickson LM, Jacobson DA, Tamarina N, Roe MW, Philipson LH, Wicksteed B.

Diabetes. 2013 May;62(5):1527-36. doi: 10.2337/db12-1013. Epub 2013 Jan 24.

PMID:
23349500
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A computational systems analysis of factors regulating α cell glucagon secretion.

Fridlyand LE, Philipson LH.

Islets. 2012 Jul-Aug;4(4):262-83. doi: 10.4161/isl.22193. Epub 2012 Jul 1.

PMID:
23093806
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion.

Rajan S, Torres J, Thompson MS, Philipson LH.

Am J Physiol Endocrinol Metab. 2012 Mar 15;302(6):E714-23. doi: 10.1152/ajpendo.00486.2011. Epub 2012 Jan 10.

PMID:
22234371
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment.

Greeley SA, Naylor RN, Philipson LH, Bell GI.

Curr Diab Rep. 2011 Dec;11(6):519-32. doi: 10.1007/s11892-011-0234-7. Review.

PMID:
21993633
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Creation of the Web-based University of Chicago Monogenic Diabetes Registry: using technology to facilitate longitudinal study of rare subtypes of diabetes.

Greeley SA, Naylor RN, Cook LS, Tucker SE, Lipton RB, Philipson LH.

J Diabetes Sci Technol. 2011 Jul 1;5(4):879-86.

PMID:
21880229
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genetics and pathophysiology of neonatal diabetes mellitus.

Naylor RN, Greeley SA, Bell GI, Philipson LH.

J Diabetes Investig. 2011 Jun 5;2(3):158-69. doi: 10.1111/j.2040-1124.2011.00106.x. Review.

PMID:
24843477
[PubMed]
Free PMC Article
13.

The cost-effectiveness of personalized genetic medicine: the case of genetic testing in neonatal diabetes.

Greeley SA, John PM, Winn AN, Ornelas J, Lipton RB, Philipson LH, Bell GI, Huang ES.

Diabetes Care. 2011 Mar;34(3):622-7. doi: 10.2337/dc10-1616. Epub 2011 Jan 27.

PMID:
21273495
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.

Støy J, Steiner DF, Park SY, Ye H, Philipson LH, Bell GI.

Rev Endocr Metab Disord. 2010 Sep;11(3):205-15. doi: 10.1007/s11154-010-9151-3. Review. Erratum in: Rev Endocr Metab Disord. 2012 Mar;13(1):79-81.

PMID:
20938745
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Intraperitoneal injection into adult zebrafish.

Kinkel MD, Eames SC, Philipson LH, Prince VE.

J Vis Exp. 2010 Aug 30;(42). pii: 2126. doi: 10.3791/2126.

PMID:
20834219
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.

Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG Jr, Gannon M, Powers AC, Dempsey PJ.

Diabetes. 2010 Dec;59(12):3090-8. doi: 10.2337/db10-0624. Epub 2010 Aug 29.

PMID:
20802254
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Glucose-induced ERM protein activation and translocation regulates insulin secretion.

Lopez JP, Turner JR, Philipson LH.

Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E772-85. doi: 10.1152/ajpendo.00199.2010. Epub 2010 Aug 24.

PMID:
20739507
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.

Jacobson DA, Mendez F, Thompson M, Torres J, Cochet O, Philipson LH.

J Physiol. 2010 Sep 15;588(Pt 18):3525-37. doi: 10.1113/jphysiol.2010.190207. Epub 2010 Jul 19.

PMID:
20643768
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.

Fridlyand LE, Tamarina N, Philipson LH.

Am J Physiol Endocrinol Metab. 2010 Oct;299(4):E517-32. doi: 10.1152/ajpendo.00177.2010. Epub 2010 Jul 13. Review.

PMID:
20628025
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.

Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J.

Nature. 2010 Jul 29;466(7306):627-31. doi: 10.1038/nature09253.

PMID:
20562852
[PubMed - indexed for MEDLINE]
Free PMC Article

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