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Closing gaps between open software and public data in a hackathon setting: User-centered software prototyping.

Busby B, Lesko M; August 2015 and January 2016 Hackathon participants, Federer L.

F1000Res. 2016 Apr 13;5:672. doi: 10.12688/f1000research.8382.1. eCollection 2016.


Reply to the commentary: Estimating genotype and allele frequencies of the CYP2D6 gene.

Varela NM, Quiñones LA.

Pharmacol Res. 2016 Apr 27. pii: S1043-6618(16)30319-X. doi: 10.1016/j.phrs.2016.04.013. [Epub ahead of print] No abstract available.


Single base resolution analysis of 5-hydroxymethylcytosine in 188 human genes: implications for hepatic gene expression.

Ivanov M, Kals M, Lauschke V, Barragan I, Ewels P, Käller M, Axelsson T, Lehtiö J, Milani L, Ingelman-Sundberg M.

Nucleic Acids Res. 2016 Apr 29. pii: gkw316. [Epub ahead of print]


Xenobiotic nuclear receptors, new tricks for an old dog.

Xie W.

Biochim Biophys Acta. 2016 Apr 27. pii: S1874-9399(16)30079-7. doi: 10.1016/j.bbagrm.2016.04.011. [Epub ahead of print] No abstract available.


Pharmacogenetics: A hope for difficult to treat chronic pain patients.

Mahajan R.

Int J Appl Basic Med Res. 2016 Apr-Jun;6(2):77-8. doi: 10.4103/2229-516X.179013. No abstract available.


Prediction models for platinum-based chemotherapy response and toxicity in advanced NSCLC patients.

Yin JY, Li X, Li XP, Xiao L, Zheng W, Chen J, Mao CX, Fang C, Cui JJ, Guo CX, Zhang W, Gao Y, Zhang CF, Chen ZH, Zhou H, Zhou HH, Liu ZQ.

Cancer Lett. 2016 Apr 25;377(1):65-73. doi: 10.1016/j.canlet.2016.04.029. [Epub ahead of print]


Long-term effect of rifampicin-based anti-TB regimen co-administration on the pharmacokinetic parameters of efavirenz and 8-hydroxy-efavirenz in HIV infected and TB-HIV co-infected Ethiopian patients.

Habtewold A, Akillu E, Makonnen E, Amogne W, Yimer G, Aderaye G, Bertilsson L, Owen JS, Burhenne J.

J Clin Pharmacol. 2016 Apr 29. doi: 10.1002/jcph.756. [Epub ahead of print]


A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract.

Chang C, Zhang K, Veluchamy A, Hébert HL, Looker HC, Colhoun HM, Palmer CN, Meng W.

Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2246-50. doi: 10.1167/iovs.16-19332.


Interferon-gamma Genetic Polymorphism and Expression in Kawasaki Disease.

Huang YH, Hsu YW, Lu HF, Wong HS, Yu HR, Kuo HC, Huang FC, Chang WC, Kuo HC.

Medicine (Baltimore). 2016 Apr;95(17):e3501. doi: 10.1097/MD.0000000000003501.


Information Needs in the Precision Medicine Era: How Genetics Home Reference Can Help.

Collins H, Calvo S, Greenberg K, Forman Neall L, Morrison S.

Interact J Med Res. 2016 Apr 27;5(2):e13. doi: 10.2196/ijmr.5199.


An expanded pharmacogenomics warfarin dosing table with utility in generalised dosing guidance.

Shahabi P, Scheinfeldt LB, Lynch DE, Schmidlen TJ, Perreault S, Keller MA, Kasper R, Wawak L, Jarvis JP, Gerry NP, Gordon ES, Christman MF, Dubé MP, Gharani N.

Thromb Haemost. 2016 Apr 28;116(2). [Epub ahead of print]


Polyphenols from Chilean Propolis and Pinocembrin Reduce MMP-9 Gene Expression and Activity in Activated Macrophages.

Saavedra N, Cuevas A, Cavalcante MF, Dörr FA, Saavedra K, Zambrano T, Abdalla DS, Salazar LA.

Biomed Res Int. 2016;2016:6505383. doi: 10.1155/2016/6505383. Epub 2016 Mar 28.


Effect of Single Nucleotide Polymorphisms in the Xenobiotic-sensing Receptors NR1I2 and NR1I3 on the Pharmacokinetics and Toxicity of Irinotecan in Colorectal Cancer Patients.

Mbatchi LC, Robert J, Ychou M, Boyer JC, Del Rio M, Gassiot M, Thomas F, Tubiana N, Evrard A.

Clin Pharmacokinet. 2016 Apr 26. [Epub ahead of print]


Transferrin Level Before Treatment and Genetic Polymorphism in HFE Gene as Predictive Markers for Response to Adalimumab in Crohn's Disease Patients.

Repnik K, Koder S, Skok P, Ferkolj I, Potočnik U.

Biochem Genet. 2016 Apr 26. [Epub ahead of print]


Association between GNB3 c.825C > T polymorphism and the risk of overweight and obesity: A meta-analysis.

Li HL, Zhang YJ, Chen XP, Luo JQ, Liu SY, Zhang ZL.

Meta Gene. 2016 Mar 18;9:18-25. doi: 10.1016/j.mgene.2016.03.002. eCollection 2016 Sep.


Methylomic changes during conversion to psychosis.

Kebir O, Chaumette B, Rivollier F, Miozzo F, Lemieux Perreault LP, Barhdadi A, Provost S, Plaze M, Bourgin J; ICAAR team, Gaillard R, Mezger V, Dubé MP, Krebs MO.

Mol Psychiatry. 2016 Apr 26. doi: 10.1038/mp.2016.53. [Epub ahead of print]


Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.

Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T.

Mol Neurodegener. 2016 Apr 26;11(1):31. doi: 10.1186/s13024-016-0095-2.


Individualized versus standardized risk assessment in patients at high risk for adverse drug reactions (IDrug) - study protocol for a pragmatic randomized controlled trial.

Stingl JC, Kaumanns KL, Claus K, Lehmann ML, Kastenmüller K, Bleckwenn M, Hartmann G, Steffens M, Wirtz D, Leuchs AK, Benda N, Meier F, Schöffski O, Holdenrieder S, Coch C, Weckbecker K.

BMC Fam Pract. 2016 Apr 26;17:49. doi: 10.1186/s12875-016-0447-6.


Lipopolysacharide rapidly and completely suppresses AgRP neuron-mediated food intake in male mice.

Liu Y, Huang Y, Liu T, Wu H, Cui H, Gautron L.

Endocrinology. 2016 Apr 25:en20152081. [Epub ahead of print]


Advances in the genetics of schizophrenia: toward a network and pathway view for drug discovery.

Collier DA, Eastwood BJ, Malki K, Mokrab Y.

Ann N Y Acad Sci. 2016 Feb;1366(1):61-75. doi: 10.1111/nyas.13066.

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