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Items: 1 to 20 of 63

1.

Protective and detrimental effects of neuroectodermal cell-derived tissue factor in mouse models of stroke.

Wang S, Reeves B, Sparkenbaugh EM, Russell J, Soltys Z, Zhang H, Faber JE, Key NS, Kirchhofer D, Granger DN, Mackman N, Pawlinski R.

JCI Insight. 2016 Jul 21;1(11). pii: e86663.

2.

Astrocyte tissue factor controls CNS hemostasis and autoimmune inflammation.

Wang S, Reeves B, Pawlinski R.

Thromb Res. 2016 May;141 Suppl 2:S65-7. doi: 10.1016/S0049-3848(16)30369-3.

PMID:
27207429
3.

The design and synthesis of new synthetic low-molecular-weight heparins.

Chandarajoti K, Liu J, Pawlinski R.

J Thromb Haemost. 2016 Jun;14(6):1135-45. doi: 10.1111/jth.13312. Epub 2016 Apr 15. Review.

PMID:
26990516
4.

Tissue factor deficiency increases alveolar hemorrhage and death in influenza A virus-infected mice.

Antoniak S, Tatsumi K, Hisada Y, Milner JJ, Neidich SD, Shaver CM, Pawlinski R, Beck MA, Bastarache JA, Mackman N.

J Thromb Haemost. 2016 Jun;14(6):1238-48. doi: 10.1111/jth.13307. Epub 2016 Apr 5.

PMID:
26947929
5.

Thrombin-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease.

Sparkenbaugh EM, Chantrathammachart P, Chandarajoti K, Mackman N, Key NS, Pawlinski R.

Blood. 2016 Mar 10;127(10):1371-3. doi: 10.1182/blood-2015-11-681114. Epub 2016 Jan 27. No abstract available.

PMID:
26817955
6.

In vitro and in vivo characterization of a reversible synthetic heparin analog.

Whelihan MF, Cooley B, Xu Y, Pawlinski R, Liu J, Key NS.

Thromb Res. 2016 Feb;138:121-9. doi: 10.1016/j.thromres.2015.12.007. Epub 2015 Dec 10.

PMID:
26709038
7.

It's "PT" for SCD!

Pawlinski R.

Blood. 2015 Oct 8;126(15):1739-40. doi: 10.1182/blood-2015-08-666594.

PMID:
26450955
8.

Hepatocyte tissue factor contributes to the hypercoagulable state in a mouse model of chronic liver injury.

Rautou PE, Tatsumi K, Antoniak S, Owens AP 3rd, Sparkenbaugh E, Holle LA, Wolberg AS, Kopec AK, Pawlinski R, Luyendyk JP, Mackman N.

J Hepatol. 2016 Jan;64(1):53-9. doi: 10.1016/j.jhep.2015.08.017. Epub 2015 Aug 29.

PMID:
26325534
9.

Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2.

Maharshak N, Huh EY, Paiboonrungruang C, Shanahan M, Thurlow L, Herzog J, Djukic Z, Orlando R, Pawlinski R, Ellermann M, Borst L, Patel S, Dotan I, Sartor RB, Carroll IM.

Infect Immun. 2015 Jul;83(7):2762-70. doi: 10.1128/IAI.00425-15. Epub 2015 Apr 27.

10.

Excess of heme induces tissue factor-dependent activation of coagulation in mice.

Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R.

Haematologica. 2015 Mar;100(3):308-14. doi: 10.3324/haematol.2014.114728. Epub 2015 Jan 16.

11.

The contribution of tumor and host tissue factor expression to oncogene-driven gliomagenesis.

Magnus N, Meehan B, Garnier D, Hashemi M, Montermini L, Lee TH, Milsom C, Pawlinski R, Ohlfest J, Anderson M, Mackman N, Rak J.

Biochem Biophys Res Commun. 2014 Nov 14;454(2):262-8. Epub 2014 Oct 23.

PMID:
25450387
12.

Tissue factor, protease activated receptors and pathologic heart remodelling.

Antoniak S, Sparkenbaugh E, Pawlinski R.

Thromb Haemost. 2014 Nov;112(5):893-900. doi: 10.1160/TH14-03-0243. Epub 2014 Aug 7. Review.

13.

Hemostasis: old system, new players, new directions.

Hoffman M, Pawlinski R.

Thromb Res. 2014 May;133 Suppl 1:S1-2. doi: 10.1016/j.thromres.2014.03.001.

PMID:
24759130
14.

De novo synthesis of a narrow size distribution low-molecular-weight heparin.

Chandarajoti K, Xu Y, Sparkenbaugh E, Key NS, Pawlinski R, Liu J.

Glycobiology. 2014 May;24(5):476-86. doi: 10.1093/glycob/cwu016. Epub 2014 Mar 13.

15.

Homogeneous low-molecular-weight heparins with reversible anticoagulant activity.

Xu Y, Cai C, Chandarajoti K, Hsieh PH, Li L, Pham TQ, Sparkenbaugh EM, Sheng J, Key NS, Pawlinski R, Harris EN, Linhardt RJ, Liu J.

Nat Chem Biol. 2014 Apr;10(4):248-50. doi: 10.1038/nchembio.1459. Epub 2014 Feb 23.

16.

Inhibit the calpain to climb the mountain.

Pawlinski R.

Blood. 2014 Feb 20;123(8):1123-4. doi: 10.1182/blood-2013-12-543397. No abstract available.

17.

Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations.

Magnus N, Garnier D, Meehan B, McGraw S, Lee TH, Caron M, Bourque G, Milsom C, Jabado N, Trasler J, Pawlinski R, Mackman N, Rak J.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3544-9. doi: 10.1073/pnas.1314118111. Epub 2014 Feb 11.

18.

Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.

Sparkenbaugh EM, Chantrathammachart P, Mickelson J, van Ryn J, Hebbel RP, Monroe DM, Mackman N, Key NS, Pawlinski R.

Blood. 2014 Mar 13;123(11):1747-56. doi: 10.1182/blood-2013-08-523936. Epub 2014 Jan 21.

19.

Protease activated receptor-2 contributes to heart failure.

Antoniak S, Sparkenbaugh EM, Tencati M, Rojas M, Mackman N, Pawlinski R.

PLoS One. 2013 Nov 27;8(11):e81733. doi: 10.1371/journal.pone.0081733. eCollection 2013.

20.

Interplay between coagulation and vascular inflammation in sickle cell disease.

Sparkenbaugh E, Pawlinski R.

Br J Haematol. 2013 Jul;162(1):3-14. doi: 10.1111/bjh.12336. Epub 2013 Apr 18. Review.

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