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Results: 1 to 20 of 55

1.

Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2.

Maharshak N, Huh EY, Paiboonrungruang C, Shanahan M, Thurlow L, Herzog J, Djukic Z, Orlando R, Pawlinski R, Ellermann M, Borst L, Patel S, Dotan I, Sartor RB, Carroll IM.

Infect Immun. 2015 Jul;83(7):2762-70. doi: 10.1128/IAI.00425-15. Epub 2015 Apr 27.

PMID:
25916983
2.

Excess of heme induces tissue factor-dependent activation of coagulation in mice.

Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R.

Haematologica. 2015 Mar;100(3):308-14. doi: 10.3324/haematol.2014.114728. Epub 2015 Jan 16.

3.

The contribution of tumor and host tissue factor expression to oncogene-driven gliomagenesis.

Magnus N, Meehan B, Garnier D, Hashemi M, Montermini L, Lee TH, Milsom C, Pawlinski R, Ohlfest J, Anderson M, Mackman N, Rak J.

Biochem Biophys Res Commun. 2014 Nov 14;454(2):262-8. Epub 2014 Oct 23.

PMID:
25450387
4.

Tissue factor, protease activated receptors and pathologic heart remodelling.

Antoniak S, Sparkenbaugh E, Pawlinski R.

Thromb Haemost. 2014 Nov;112(5):893-900. doi: 10.1160/TH14-03-0243. Epub 2014 Aug 7.

PMID:
25104210
5.

Hemostasis: old system, new players, new directions.

Hoffman M, Pawlinski R.

Thromb Res. 2014 May;133 Suppl 1:S1-2. doi: 10.1016/j.thromres.2014.03.001.

PMID:
24759130
6.

De novo synthesis of a narrow size distribution low-molecular-weight heparin.

Chandarajoti K, Xu Y, Sparkenbaugh E, Key NS, Pawlinski R, Liu J.

Glycobiology. 2014 May;24(5):476-86. doi: 10.1093/glycob/cwu016. Epub 2014 Mar 13.

7.

Homogeneous low-molecular-weight heparins with reversible anticoagulant activity.

Xu Y, Cai C, Chandarajoti K, Hsieh PH, Li L, Pham TQ, Sparkenbaugh EM, Sheng J, Key NS, Pawlinski R, Harris EN, Linhardt RJ, Liu J.

Nat Chem Biol. 2014 Apr;10(4):248-50. doi: 10.1038/nchembio.1459. Epub 2014 Feb 23.

8.

Inhibit the calpain to climb the mountain.

Pawlinski R.

Blood. 2014 Feb 20;123(8):1123-4. doi: 10.1182/blood-2013-12-543397. No abstract available.

9.

Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations.

Magnus N, Garnier D, Meehan B, McGraw S, Lee TH, Caron M, Bourque G, Milsom C, Jabado N, Trasler J, Pawlinski R, Mackman N, Rak J.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3544-9. doi: 10.1073/pnas.1314118111. Epub 2014 Feb 11.

10.

Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.

Sparkenbaugh EM, Chantrathammachart P, Mickelson J, van Ryn J, Hebbel RP, Monroe DM, Mackman N, Key NS, Pawlinski R.

Blood. 2014 Mar 13;123(11):1747-56. doi: 10.1182/blood-2013-08-523936. Epub 2014 Jan 21.

11.

Protease activated receptor-2 contributes to heart failure.

Antoniak S, Sparkenbaugh EM, Tencati M, Rojas M, Mackman N, Pawlinski R.

PLoS One. 2013 Nov 27;8(11):e81733. doi: 10.1371/journal.pone.0081733. eCollection 2013.

12.

Interplay between coagulation and vascular inflammation in sickle cell disease.

Sparkenbaugh E, Pawlinski R.

Br J Haematol. 2013 Jul;162(1):3-14. doi: 10.1111/bjh.12336. Epub 2013 Apr 18. Review.

13.

PAR-1 contributes to the innate immune response during viral infection.

Antoniak S, Owens AP 3rd, Baunacke M, Williams JC, Lee RD, Weithäuser A, Sheridan PA, Malz R, Luyendyk JP, Esserman DA, Trejo J, Kirchhofer D, Blaxall BC, Pawlinski R, Beck MA, Rauch U, Mackman N.

J Clin Invest. 2013 Mar;123(3):1310-22. doi: 10.1172/JCI66125. Epub 2013 Feb 8.

14.

Dysregulated coagulation associated with hypofibrinogenaemia and plasma hypercoagulability: implications for identifying coagulopathic mechanisms in humans.

Marchi R, Walton BL, McGary CS, Lin FC, Ma AD, Pawlinski R, Mackman N, Campbell RA, Di Paola J, Wolberg AS.

Thromb Haemost. 2012 Sep;108(3):516-26. doi: 10.1160/TH12-05-0355. Epub 2012 Jul 26.

15.

Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease.

Chantrathammachart P, Mackman N, Sparkenbaugh E, Wang JG, Parise LV, Kirchhofer D, Key NS, Pawlinski R.

Blood. 2012 Jul 19;120(3):636-46. doi: 10.1182/blood-2012-04-424143. Epub 2012 Jun 1.

16.

Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer.

Wang JG, Geddings JE, Aleman MM, Cardenas JC, Chantrathammachart P, Williams JC, Kirchhofer D, Bogdanov VY, Bach RR, Rak J, Church FC, Wolberg AS, Pawlinski R, Key NS, Yeh JJ, Mackman N.

Blood. 2012 Jun 7;119(23):5543-52. doi: 10.1182/blood-2012-01-402156. Epub 2012 Apr 30.

17.

Tissue factor and thrombin in sickle cell anemia.

Chantrathammachart P, Pawlinski R.

Thromb Res. 2012 May;129 Suppl 2:S70-2. doi: 10.1016/j.thromres.2012.02.038. Epub 2012 Mar 6. Review.

18.

PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI.

Kasthuri RS, Glover SL, Jonas W, McEachron T, Pawlinski R, Arepally GM, Key NS, Mackman N.

Blood. 2012 May 31;119(22):5285-93. doi: 10.1182/blood-2011-06-359430. Epub 2012 Mar 6.

19.

We can do it together: PAR1/PAR2 heterodimer signaling in VSMCs.

Pawlinski R, Holinstat M.

Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2775-6. doi: 10.1161/ATVBAHA.111.238865. No abstract available.

20.

Protease-activated receptors and myocardial infarction.

Antoniak S, Pawlinski R, Mackman N.

IUBMB Life. 2011 Jun;63(6):383-9. doi: 10.1002/iub.441. Epub 2011 Mar 24. Review.

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