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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1988 1
2008 1
2010 2
2011 1
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2016 2
2018 1
2019 3
2020 1
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2023 7
2024 2

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28 results

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Page 1
Patient-derived cancer organoids for drug screening: Basic technology and clinical application.
Ren X, Chen W, Yang Q, Li X, Xu L. Ren X, et al. J Gastroenterol Hepatol. 2022 Aug;37(8):1446-1454. doi: 10.1111/jgh.15930. Epub 2022 Jul 7. J Gastroenterol Hepatol. 2022. PMID: 35771719 Review.
Cancer organoids, a three-dimensional (3D) culture system of cancer cells derived from tumor tissues, recapitulate physiological structure of the parental tumor. Different tumor organoids have been established for a variety of tumor types, such as colorectal, liver, stomac …
Cancer organoids, a three-dimensional (3D) culture system of cancer cells derived from tumor tissues, recapitulate physiological stru …
Vascular organoids: unveiling advantages, applications, challenges, and disease modelling strategies.
Naderi-Meshkin H, Cornelius VA, Eleftheriadou M, Potel KN, Setyaningsih WAW, Margariti A. Naderi-Meshkin H, et al. Stem Cell Res Ther. 2023 Oct 10;14(1):292. doi: 10.1186/s13287-023-03521-2. Stem Cell Res Ther. 2023. PMID: 37817281 Free PMC article. Review.
Therefore, here we explore different aspects for the development of advanced 3D in vitro disease models that recapitulate human blood vessel complications using patient-derived induced pluripotent stem cells, which retain the epigenetic, transcriptomic, and metabolic memor …
Therefore, here we explore different aspects for the development of advanced 3D in vitro disease models that recapitulate human blood …
Musculoskeletal regeneration: A zebrafish perspective.
Kaliya-Perumal AK, Ingham PW. Kaliya-Perumal AK, et al. Biochimie. 2022 May;196:171-181. doi: 10.1016/j.biochi.2021.10.014. Epub 2021 Oct 27. Biochimie. 2022. PMID: 34715269 Review.
Moreover, clinically relevant muscle and skeletal injury zebrafish models recapitulate mammalian regeneration. Upon muscle injury, quiescent stem cells - known as satellite cells - become activated, proliferate, differentiate and fuse to form new myofibres, while bone frac …
Moreover, clinically relevant muscle and skeletal injury zebrafish models recapitulate mammalian regeneration. Upon muscle injury, qu …
In Vitro Embryogenesis and Gastrulation Using Stem Cells in Mice and Humans.
Oh SY, Na SB, Kang YK, Do JT. Oh SY, et al. Int J Mol Sci. 2023 Sep 4;24(17):13655. doi: 10.3390/ijms241713655. Int J Mol Sci. 2023. PMID: 37686459 Free PMC article. Review.
These in vitro models closely resemble early embryos in terms of morphology and gene expression and provide a faithful recapitulation of early pre- and post-implantation embryonic development. ...Furthermore, recent findings and breakthroughs in synthetic embryos and gastr …
These in vitro models closely resemble early embryos in terms of morphology and gene expression and provide a faithful recapitulation …
Spinal Cord Organoids to Study Motor Neuron Development and Disease.
Buchner F, Dokuzluoglu Z, Grass T, Rodriguez-Muela N. Buchner F, et al. Life (Basel). 2023 May 25;13(6):1254. doi: 10.3390/life13061254. Life (Basel). 2023. PMID: 37374039 Free PMC article. Review.
Pluripotent stem cell (PSC)-based protocols to generate SpC-like structures, sometimes including the adjacent mesoderm and derived skeletal muscle, are constantly being refined and applied to study early human neuromuscular development and disease. In this review, we outline …
Pluripotent stem cell (PSC)-based protocols to generate SpC-like structures, sometimes including the adjacent mesoderm and derived skeletal …
Personalized 3D printed bone scaffolds: A review.
Mirkhalaf M, Men Y, Wang R, No Y, Zreiqat H. Mirkhalaf M, et al. Acta Biomater. 2023 Jan 15;156:110-124. doi: 10.1016/j.actbio.2022.04.014. Epub 2022 Apr 13. Acta Biomater. 2023. PMID: 35429670 Review.
Significant progress has been made over the past decade in additive manufacturing techniques to 3D print bone grafts, but challenges remain in the lack of manufacturing techniques that can recapitulate both mechanical and biological functions of native bones. ...The articl …
Significant progress has been made over the past decade in additive manufacturing techniques to 3D print bone grafts, but challenges remain …
The generation and properties of human cortical organoids as a disease model for malformations of cortical development.
Zhang XP, Wang XY, Wang SN, Miao CY. Zhang XP, et al. Neural Regen Res. 2023 Oct;18(10):2119-2126. doi: 10.4103/1673-5374.369100. Neural Regen Res. 2023. PMID: 37056118 Free PMC article. Review.
In addition to studying the neuro-electrophysiological features of brain cortex development, human cortical organoids have been widely used to mimic the pathophysiological features of cortical-related disease, especially in mimicking malformations of cortical development, thus re …
In addition to studying the neuro-electrophysiological features of brain cortex development, human cortical organoids have been widely used …
Structure determination using solution NMR: Is it worth the effort?
Takeuchi K, Baskaran K, Arthanari H. Takeuchi K, et al. J Magn Reson. 2019 Sep;306:195-201. doi: 10.1016/j.jmr.2019.07.045. Epub 2019 Jul 13. J Magn Reson. 2019. PMID: 31345771 Review.
The field has continually developed methodology and instrumentation since its introduction, pushing its frontiers and redefining its limits. Here we present a brief overview of NMR-based structure determination over the past 40 years. We outline the current state of …
The field has continually developed methodology and instrumentation since its introduction, pushing its frontiers and redefining its limits. …
Advances in cardiac tissue engineering and heart-on-a-chip.
Kieda J, Shakeri A, Landau S, Wang EY, Zhao Y, Lai BF, Okhovatian S, Wang Y, Jiang R, Radisic M. Kieda J, et al. J Biomed Mater Res A. 2024 Apr;112(4):492-511. doi: 10.1002/jbm.a.37633. Epub 2023 Nov 1. J Biomed Mater Res A. 2024. PMID: 37909362 Review.
Heart-on-a-chip platforms are now commonly used by a number of pharmaceutical and biotechnology companies. Here, we provide an overview of cardiac physiology in order to better define the requirements for functional tissue recapitulation. We then discuss the biomate …
Heart-on-a-chip platforms are now commonly used by a number of pharmaceutical and biotechnology companies. Here, we provide an overview …
Organ-On-Chip Technology: The Future of Feto-Maternal Interface Research?
Richardson L, Kim S, Menon R, Han A. Richardson L, et al. Front Physiol. 2020 Jun 30;11:715. doi: 10.3389/fphys.2020.00715. eCollection 2020. Front Physiol. 2020. PMID: 32695021 Free PMC article. Review.
The emergence of in vivo-like in vitro models such as organ-on-chip (OOC) platforms can better recapitulate in vivo functions and responses and has the potential to move this field forward significantly. ...As a vital component of this review, we aim to outline prog …
The emergence of in vivo-like in vitro models such as organ-on-chip (OOC) platforms can better recapitulate in vivo functions and res …
28 results