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Results: 1 to 20 of 26

1.

Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injury.

Arif E, Rathore YS, Kumari B, Ashish F, Wong HN, Holzman LB, Nihalani D.

J Biol Chem. 2014 Apr 4;289(14):9502-18. doi: 10.1074/jbc.M113.505743. Epub 2014 Feb 19.

PMID:
24554715
[PubMed - indexed for MEDLINE]
2.

Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis.

George B, Fan Q, Dlugos CP, Soofi AA, Zhang J, Verma R, Park TJ, Wong H, Curran T, Nihalani D, Holzman LB.

Kidney Int. 2014 Jun;85(6):1382-94. doi: 10.1038/ki.2013.556. Epub 2014 Feb 5.

PMID:
24499776
[PubMed - in process]
3.

Sirt1-Claudin-1 crosstalk regulates renal function.

Nihalani D, Susztak K.

Nat Med. 2013 Nov;19(11):1371-2. doi: 10.1038/nm.3386. No abstract available.

PMID:
24202384
[PubMed - indexed for MEDLINE]
4.

Myo1c is an unconventional myosin required for zebrafish glomerular development.

Arif E, Kumari B, Wagner MC, Zhou W, Holzman LB, Nihalani D.

Kidney Int. 2013 Dec;84(6):1154-65. doi: 10.1038/ki.2013.201. Epub 2013 May 29.

PMID:
23715127
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

APOL1 null alleles from a rural village in India do not correlate with glomerulosclerosis.

Johnstone DB, Shegokar V, Nihalani D, Rathore YS, Mallik L, Ashish, Zare V, Ikizler HO, Powar R, Holzman LB.

PLoS One. 2012;7(12):e51546. doi: 10.1371/journal.pone.0051546. Epub 2012 Dec 26.

PMID:
23300552
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling.

Tiwari A, Jung JJ, Inamdar SM, Nihalani D, Choudhury A.

Am J Physiol Heart Circ Physiol. 2013 Mar 1;304(5):H687-96. doi: 10.1152/ajpheart.00744.2012. Epub 2012 Dec 21.

PMID:
23262137
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Functional study of mammalian Neph proteins in Drosophila melanogaster.

Helmstädter M, Lüthy K, Gödel M, Simons M, Ashish, Nihalani D, Rensing SA, Fischbach KF, Huber TB.

PLoS One. 2012;7(7):e40300. doi: 10.1371/journal.pone.0040300. Epub 2012 Jul 6.

PMID:
22792268
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Diminished functional role and altered localization of SHP2 in non-small cell lung cancer cells with EGFR-activating mutations.

Furcht CM, Muñoz Rojas AR, Nihalani D, Lazzara MJ.

Oncogene. 2013 May 2;32(18):2346-55, 2355.e1-10. doi: 10.1038/onc.2012.240. Epub 2012 Jul 9.

PMID:
22777356
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Solution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS).

Mallik L, Arif E, Sharma P, Rathore YS, Wong HN, Holzman LB, Ashish, Nihalani D.

J Biol Chem. 2012 Mar 16;287(12):9441-53. doi: 10.1074/jbc.M111.284927. Epub 2012 Jan 17.

PMID:
22262837
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.

George B, Verma R, Soofi AA, Garg P, Zhang J, Park TJ, Giardino L, Ryzhova L, Johnstone DB, Wong H, Nihalani D, Salant DJ, Hanks SK, Curran T, Rastaldi MP, Holzman LB.

J Clin Invest. 2012 Feb 1;122(2):674-92. doi: 10.1172/JCI60070. Epub 2012 Jan 17.

PMID:
22251701
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Visual insight into how low pH alone can induce actin-severing ability in gelsolin under calcium-free conditions.

Garg R, Peddada N, Sagar A, Nihalani D, Ashish.

J Biol Chem. 2011 Jun 10;286(23):20387-97. doi: 10.1074/jbc.M111.236943. Epub 2011 Apr 15.

PMID:
21498516
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane.

Arif E, Wagner MC, Johnstone DB, Wong HN, George B, Pruthi PA, Lazzara MJ, Nihalani D.

Mol Cell Biol. 2011 May;31(10):2134-50. doi: 10.1128/MCB.05051-11. Epub 2011 Mar 14.

PMID:
21402783
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1.

Wagner MC, Rhodes G, Wang E, Pruthi V, Arif E, Saleem MA, Wean SE, Garg P, Verma R, Holzman LB, Gattone V, Molitoris BA, Nihalani D.

J Biol Chem. 2008 Dec 19;283(51):35579-89. doi: 10.1074/jbc.M805507200. Epub 2008 Oct 14.

PMID:
18922801
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization.

Garg P, Verma R, Nihalani D, Johnstone DB, Holzman LB.

Mol Cell Biol. 2007 Dec;27(24):8698-712. Epub 2007 Oct 8.

PMID:
17923684
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Src family kinases directly regulate JIP1 module dynamics and activation.

Nihalani D, Wong H, Verma R, Holzman LB.

Mol Cell Biol. 2007 Apr;27(7):2431-41. Epub 2007 Jan 22.

PMID:
17242197
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.

Verma R, Kovari I, Soofi A, Nihalani D, Patrie K, Holzman LB.

J Clin Invest. 2006 May;116(5):1346-59. Epub 2006 Mar 16.

PMID:
16543952
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Inhibition of membrane depolarisation-induced transcriptional activity of cyclic AMP response element binding protein (CREB) by the dual-leucine-zipper-bearing kinase in a pancreatic islet beta cell line.

Oetjen E, Lechleiter A, Blume R, Nihalani D, Holzman L, Knepel W.

Diabetologia. 2006 Feb;49(2):332-42. Epub 2005 Dec 21.

PMID:
16369771
[PubMed - indexed for MEDLINE]
18.

Recruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activation.

Nihalani D, Wong HN, Holzman LB.

J Biol Chem. 2003 Aug 1;278(31):28694-702. Epub 2003 May 19.

PMID:
12756254
[PubMed - indexed for MEDLINE]
Free Article
19.

Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin.

Verma R, Wharram B, Kovari I, Kunkel R, Nihalani D, Wary KK, Wiggins RC, Killen P, Holzman LB.

J Biol Chem. 2003 Jun 6;278(23):20716-23. Epub 2003 Mar 31. Erratum in: J Biol Chem. 2005 Jul 15;280(28):26640.

PMID:
12668668
[PubMed - indexed for MEDLINE]
Free Article
20.

Phosphorylation of Pax2 by the c-Jun N-terminal kinase and enhanced Pax2-dependent transcription activation.

Cai Y, Lechner MS, Nihalani D, Prindle MJ, Holzman LB, Dressler GR.

J Biol Chem. 2002 Jan 11;277(2):1217-22. Epub 2001 Nov 7.

PMID:
11700324
[PubMed - indexed for MEDLINE]
Free Article

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