QTc prolongation and torsades de pointes associated with methadone therapy.
J Emerg Med. 2007.
PMID: 17394991
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Methadone, QTc prolongation and torsades de pointes: Current concepts, management and a hidden twist in the tale?
J Cardiovasc Dis Res. 2013.
PMID: 24653586
Free PMC article.
Review.
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Methadone, QTc prolongation and torsades de pointes: Current concepts, management and a hidden twist in the tale?
J Cardiovasc Dis Res. 2013 Dec;4(4):229-35. doi: 10.1016/j.jcdr.2013.10.001. Epub 2013 Nov 16.
J Cardiovasc Dis Res. 2013.
PMID: 24653586
Free PMC article.
Review.
Along with its popularity, methadone has also earned an infamous reputation for causing prolongation of the QT interval and an increased risk of torsades de pointes. ...In addition, we explore the idea and implications of a genetic link between meth …
Along with its popularity, methadone has also earned an infamous reputation for causing prolongation of the QT interval and an increa …
Methadone, Metoclopramide and Metronidazole Interaction Causing Torsades de Pointes.
Clin Pract. 2021 Feb 7;11(1):101-105. doi: 10.3390/clinpract11010015.
Clin Pract. 2021.
PMID: 33562182
Free PMC article.
There are several classes of medications that can cause prolongation of the corrected QT (QTc) interval and potentially Torsades de Pointes (TdP). Most of these medications are commonly used in the emergency department, and interaction between these me …
There are several classes of medications that can cause prolongation of the corrected QT (QTc) interval and potentially Torsades …
Loperamide-Induced Torsades de Pointes.
Cureus. 2021 Dec 9;13(12):e20299. doi: 10.7759/cureus.20299. eCollection 2021 Dec.
Cureus. 2021.
PMID: 35028205
Free PMC article.
Loperamide, an over-the-counter antidiarrheal, works on the opioid receptor with minimal opioid activity if taken as directed. Recently, it has gained popularity as the "poor man's methadone" at supratherapeutic dosing. Opioid antagonism with naloxone is beneficial in reve …
Loperamide, an over-the-counter antidiarrheal, works on the opioid receptor with minimal opioid activity if taken as directed. Recently, it …
Torsades de pointes associated with methadone and voriconazole.
BMJ Case Rep. 2009;2009:bcr07.2009.2119. doi: 10.1136/bcr.07.2009.2119. Epub 2009 Dec 22.
BMJ Case Rep. 2009.
PMID: 22190985
Free PMC article.
This report concerns a case of torsades de pointes (TdP) associated with the concomitant administration of methadone and voriconazole in a patient with comorbid medical conditions. ...He experienced multiple episodes of TdP with a prolonged QTc …
This report concerns a case of torsades de pointes (TdP) associated with the concomitant administration of methadone …
Methadone-induced Torsades de pointes.
R I Med J (2013). 2013 Jul 30;96(8):20-1.
R I Med J (2013). 2013.
PMID: 23923121
Torsades de pointes is a polymorphic ventricular tachycardia that can quickly evolve into ventricular fibrillation and sudden death. ...We report a case of methadone-induced Torsades de pointes complicated by ventricular fibrillati …
Torsades de pointes is a polymorphic ventricular tachycardia that can quickly evolve into ventricular fibrillation and …
Methadone induced torsades de pointes and ventricular fibrillation: A case review.
ARYA Atheroscler. 2014 Nov;10(6):339-42.
ARYA Atheroscler. 2014.
PMID: 25815024
Free PMC article.
This drug is a potent blocker of the delayed rectifier potassium ion channel, which may result in corrected QT (QTc) interval prolongation and increased risk of torsades de pointes (TdP) in susceptible individuals. ...Our purpose in this case review wa …
This drug is a potent blocker of the delayed rectifier potassium ion channel, which may result in corrected QT (QTc) interval prolong …
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
Cardiovasc Toxicol. 2022 Sep;22(9):866-877. doi: 10.1007/s12012-022-09764-4. Epub 2022 Aug 5.
Cardiovasc Toxicol. 2022.
PMID: 35930218
Many drugs carry some risk of QT interval prolongation, which can lead to life-threatening dysrhythmias including Torsades de Pointes (TdP). CredibleMeds.org identifies medications categorized as "Known Risk of TdP" but does not stratify risk in acute suprath …
Many drugs carry some risk of QT interval prolongation, which can lead to life-threatening dysrhythmias including Torsades de …
Methadone maintenance, QTc and torsade de pointes: who needs an electrocardiogram and what is the prevalence of QTc prolongation?
Drug Alcohol Rev. 2011 Jul;30(4):388-96. doi: 10.1111/j.1465-3362.2010.00237.x. Epub 2010 Sep 6.
Drug Alcohol Rev. 2011.
PMID: 21355918
INTRODUCTION AND AIMS: High-dose methadone has been associated with rate-corrected QT (QTc) prolongation and 'torsade de pointes'. ...QTc prolongation prevalence was 18.1% with no 'clinically significant' QTc prolongation >500 ms or to …
INTRODUCTION AND AIMS: High-dose methadone has been associated with rate-corrected QT (QTc) prolongation and 'torsade de …
Drug-induced torsades de pointes in an underserved urban population. Methadone: is there therapeutic equipoise?
J Interv Card Electrophysiol. 2016 Jan;45(1):37-45. doi: 10.1007/s10840-015-0077-2. Epub 2015 Nov 20.
J Interv Card Electrophysiol. 2016.
PMID: 26589717
Free article.
BACKGROUND: Although it has been well established that methadone use can result in prolonged QTc/torsades de pointes (TdP) and has been labeled as one of the main drugs that cause TdP, it is still prescribed indiscriminately, and several cases o …
BACKGROUND: Although it has been well established that methadone use can result in prolonged QTc/torsades de …
Opioids, QTc prolongation, and torsades.
J Clin Pharmacol. 2012 Oct;52(10):1614. doi: 10.1177/0091270011422816. Epub 2011 Oct 21.
J Clin Pharmacol. 2012.
PMID: 22021567
No abstract available.
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