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Results: 1 to 20 of 92

1.

KIT GNNK splice variants: expression in systemic mastocytosis and influence on the activating potential of the D816V mutation in mast cells.

Chan EC, Bai Y, Bandara G, Simakova O, Brittain E, Scott L, Dyer KD, Klion AD, Maric I, Gilfillan AM, Metcalfe DD, Wilson TM.

Exp Hematol. 2013 Oct;41(10):870-881.e2. doi: 10.1016/j.exphem.2013.05.005. Epub 2013 Jun 4.

PMID:
23743299
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells.

Cruse G, Beaven MA, Ashmole I, Bradding P, Gilfillan AM, Metcalfe DD.

Immunity. 2013 May 23;38(5):906-17. doi: 10.1016/j.immuni.2013.04.007. Epub 2013 May 2.

PMID:
23643722
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells.

Smrž D, Bandara G, Beaven MA, Metcalfe DD, Gilfillan AM.

Eur J Immunol. 2013 Jul;43(7):1873-82. doi: 10.1002/eji.201243214. Epub 2013 Jun 4.

PMID:
23616175
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production.

Medic N, Desai A, Olivera A, Abramowitz J, Birnbaumer L, Beaven MA, Gilfillan AM, Metcalfe DD.

Cell Calcium. 2013 May-Jun;53(5-6):315-26. doi: 10.1016/j.ceca.2013.02.001. Epub 2013 Mar 13.

PMID:
23489970
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mast cell dependent vascular changes associated with an acute response to cold immersion in primary contact urticaria.

Meyer J, Gorbach AM, Liu WM, Medic N, Young M, Nelson C, Arceo S, Desai A, Metcalfe DD, Komarow HD.

PLoS One. 2013;8(2):e56773. doi: 10.1371/journal.pone.0056773. Epub 2013 Feb 22.

PMID:
23451084
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses.

Smrž D, Bandara G, Zhang S, Mock BA, Beaven MA, Metcalfe DD, Gilfillan AM.

J Immunol Methods. 2013 Apr 30;390(1-2):52-62. doi: 10.1016/j.jim.2013.01.008. Epub 2013 Jan 25.

PMID:
23357051
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) & European Competence Network on Mastocytosis (ECNM) consensus response criteria in advanced systemic mastocytosis.

Gotlib J, Pardanani A, Akin C, Reiter A, George T, Hermine O, Kluin-Nelemans H, Hartmann K, Sperr WR, Brockow K, Schwartz LB, Orfao A, Deangelo DJ, Arock M, Sotlar K, Horny HP, Metcalfe DD, Escribano L, Verstovsek S, Tefferi A, Valent P.

Blood. 2013 Mar 28;121(13):2393-401. doi: 10.1182/blood-2012-09-458521. Epub 2013 Jan 16.

PMID:
23325841
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

IL-33 induces a hyporesponsive phenotype in human and mouse mast cells.

Jung MY, Smrž D, Desai A, Bandara G, Ito T, Iwaki S, Kang JH, Andrade MV, Hilderbrand SC, Brown JM, Beaven MA, Metcalfe DD, Gilfillan AM.

J Immunol. 2013 Jan 15;190(2):531-8. doi: 10.4049/jimmunol.1201576. Epub 2012 Dec 17.

PMID:
23248261
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Targeting the KIT activating switch control pocket: a novel mechanism to inhibit neoplastic mast cell proliferation and mast cell activation.

Bai Y, Bandara G, Ching Chan E, Maric I, Simakova O, Bandara SN, Lu WP, Wise SC, Flynn DL, Metcalfe DD, Gilfillan AM, Wilson TM.

Leukemia. 2013 Feb;27(2):278-85. doi: 10.1038/leu.2012.218. Epub 2012 Jul 31. Review.

PMID:
22907049
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Stem cell factor programs the mast cell activation phenotype.

Ito T, Smrž D, Jung MY, Bandara G, Desai A, Smržová Š, Kuehn HS, Beaven MA, Metcalfe DD, Gilfillan AM.

J Immunol. 2012 Jun 1;188(11):5428-37. doi: 10.4049/jimmunol.1103366. Epub 2012 Apr 23.

PMID:
22529299
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.

Ombrello MJ, Remmers EF, Sun G, Freeman AF, Datta S, Torabi-Parizi P, Subramanian N, Bunney TD, Baxendale RW, Martins MS, Romberg N, Komarow H, Aksentijevich I, Kim HS, Ho J, Cruse G, Jung MY, Gilfillan AM, Metcalfe DD, Nelson C, O'Brien M, Wisch L, Stone K, Douek DC, Gandhi C, Wanderer AA, Lee H, Nelson SF, Shianna KV, Cirulli ET, Goldstein DB, Long EO, Moir S, Meffre E, Holland SM, Kastner DL, Katan M, Hoffman HM, Milner JD.

N Engl J Med. 2012 Jan 26;366(4):330-8. doi: 10.1056/NEJMoa1102140. Epub 2012 Jan 11.

PMID:
22236196
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Providing the TORC for cell cycle progression in neoplastic mast cells.

Smrž D, Wilson TM, Metcalfe DD, Gilfillan AM.

Cell Cycle. 2012 Jan 15;11(2):210-1. doi: 10.4161/cc.11.2.18976. Epub 2012 Jan 15. No abstract available.

PMID:
22214664
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A study of the use of impulse oscillometry in the evaluation of children with asthma: analysis of lung parameters, order effect, and utility compared with spirometry.

Komarow HD, Skinner J, Young M, Gaskins D, Nelson C, Gergen PJ, Metcalfe DD.

Pediatr Pulmonol. 2012 Jan;47(1):18-26. doi: 10.1002/ppul.21507. Epub 2011 Aug 24.

PMID:
22170806
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.

Smrz D, Kim MS, Zhang S, Mock BA, Smrzová S, DuBois W, Simakova O, Maric I, Wilson TM, Metcalfe DD, Gilfillan AM.

Blood. 2011 Dec 22;118(26):6803-13. doi: 10.1182/blood-2011-06-359984. Epub 2011 Nov 3.

PMID:
22053105
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal.

Valent P, Akin C, Arock M, Brockow K, Butterfield JH, Carter MC, Castells M, Escribano L, Hartmann K, Lieberman P, Nedoszytko B, Orfao A, Schwartz LB, Sotlar K, Sperr WR, Triggiani M, Valenta R, Horny HP, Metcalfe DD.

Int Arch Allergy Immunol. 2012;157(3):215-25. doi: 10.1159/000328760. Epub 2011 Oct 27.

PMID:
22041891
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Glycogen synthase kinase-3β is a prosurvival signal for the maintenance of human mast cell homeostasis.

Rådinger M, Smrž D, Metcalfe DD, Gilfillan AM.

J Immunol. 2011 Dec 1;187(11):5587-95. doi: 10.4049/jimmunol.1101257. Epub 2011 Oct 28.

PMID:
22039301
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Examination of the role of TRPM8 in human mast cell activation and its relevance to the etiology of cold-induced urticaria.

Medic N, Desai A, Komarow H, Burch LH, Bandara G, Beaven MA, Metcalfe DD, Gilfillan AM.

Cell Calcium. 2011 Nov;50(5):473-80. doi: 10.1016/j.ceca.2011.08.003. Epub 2011 Sep 8.

PMID:
21906810
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Distinct PGE2-responder and non-responder phenotypes in human mast cell populations: "all or nothing" enhancement of antigen-dependent mediator release.

Kuehn HS, Jung MY, Beaven MA, Metcalfe DD, Gilfillan AM.

Immunol Lett. 2011 Dec 30;141(1):45-54. doi: 10.1016/j.imlet.2011.07.002. Epub 2011 Jul 20.

PMID:
21798286
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

IL-5 receptor α levels in patients with marked eosinophilia or mastocytosis.

Wilson TM, Maric I, Shukla J, Brown M, Santos C, Simakova O, Khoury P, Fay MP, Kozhich A, Kolbeck R, Metcalfe DD, Klion AD.

J Allergy Clin Immunol. 2011 Nov;128(5):1086-92.e1-3. doi: 10.1016/j.jaci.2011.05.032. Epub 2011 Jul 16.

PMID:
21762978
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Glycomic analysis of human mast cells, eosinophils and basophils.

North SJ, von Gunten S, Antonopoulos A, Trollope A, MacGlashan DW Jr, Jang-Lee J, Dell A, Metcalfe DD, Kirshenbaum AS, Bochner BS, Haslam SM.

Glycobiology. 2012 Jan;22(1):12-22. doi: 10.1093/glycob/cwr089. Epub 2011 Jul 1.

PMID:
21725073
[PubMed - indexed for MEDLINE]
Free PMC Article

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