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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 2
1969 1
1972 1
1976 1
1984 1
1985 3
1986 1
1987 1
1988 1
1989 2
1990 3
1991 1
1992 4
1993 1
1994 1
1995 2
1996 4
1997 4
1998 5
1999 1
2000 6
2001 8
2002 8
2003 10
2004 16
2005 24
2006 31
2007 18
2008 30
2009 29
2010 36
2011 42
2012 57
2013 46
2014 71
2015 70
2016 67
2017 74
2018 76
2019 84
2020 93
2021 103
2022 94
2023 114
2024 50

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1,130 results

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Mangiferin relieves CCl4-induced liver fibrosis in mice.
Zhang L, Liu C, Yin L, Huang C, Fan S. Zhang L, et al. Sci Rep. 2023 Mar 13;13(1):4172. doi: 10.1038/s41598-023-30582-3. Sci Rep. 2023. PMID: 36914687 Free PMC article.
Here, we investigate the effects of mangiferin on CCl4-induced liver fibrosis and the underlying mechanism in mice. ...Furthermore, mangiferin reduced collagen accumulation and HSCs activation, inhibited the p-IkappaB and p-p65 protein levels. ...
Here, we investigate the effects of mangiferin on CCl4-induced liver fibrosis and the underlying mechanism in mice. ...Furthermore, …
Mangiferin and organ fibrosis: A mini review.
Zhang L, Huang C, Fan S. Zhang L, et al. Biofactors. 2021 Jan;47(1):59-68. doi: 10.1002/biof.1693. Epub 2020 Nov 20. Biofactors. 2021. PMID: 33217771 Review.
The emerging evidence has shown that mangiferin can improve renal interstitial fibrosis, pulmonary fibrosis, myocardial fibrosis and hepatic fibrosis through the inhibition of inflammation, oxidative stress and fibrogenesis effects, indicating that mangiferin is pro …
The emerging evidence has shown that mangiferin can improve renal interstitial fibrosis, pulmonary fibrosis, myocardial fibrosis and …
Mangiferin prevents myocardial infarction-induced apoptosis and heart failure in mice by activating the Sirt1/FoxO3a pathway.
Chen L, Li S, Zhu J, You A, Huang X, Yi X, Xue M. Chen L, et al. J Cell Mol Med. 2021 Mar;25(6):2944-2955. doi: 10.1111/jcmm.16329. Epub 2021 Feb 1. J Cell Mol Med. 2021. PMID: 33523605 Free PMC article.
Mangiferin reduced OGD-induced cellular apoptosis in H9c2 cells. Meanwhile, Sirt1 knockout/silencing abolished the protective effects of mangiferin. Further studies revealed that mangiferin increased FoxO3a deacetylation by up-regulating Sirt1, thus preventin
Mangiferin reduced OGD-induced cellular apoptosis in H9c2 cells. Meanwhile, Sirt1 knockout/silencing abolished the protective effects
Mangiferin Improved Palmitate-Induced-Insulin Resistance by Promoting Free Fatty Acid Metabolism in HepG2 and C2C12 Cells via PPARalpha: Mangiferin Improved Insulin Resistance.
Zhang Q, Kong X, Yuan H, Guan H, Li Y, Niu Y. Zhang Q, et al. J Diabetes Res. 2019 Jan 27;2019:2052675. doi: 10.1155/2019/2052675. eCollection 2019. J Diabetes Res. 2019. PMID: 30809553 Free PMC article.
Our research was to determine the effects and mechanism of mangiferin on improving IR by regulating FFA metabolism in HepG2 and C2C12 cells. ...Mangiferin significantly increased FFA uptake and decreased intracellular FFA and triglyceride (TG) accumulations. ...
Our research was to determine the effects and mechanism of mangiferin on improving IR by regulating FFA metabolism in HepG2 and C2C12 …
Mangiferin: the miraculous xanthone with diverse pharmacological properties.
Dutta T, Das T, Gopalakrishnan AV, Saha SC, Ghorai M, Nandy S, Kumar M, Radha, Ghosh A, Mukerjee N, Dey A. Dutta T, et al. Naunyn Schmiedebergs Arch Pharmacol. 2023 May;396(5):851-863. doi: 10.1007/s00210-022-02373-6. Epub 2023 Jan 19. Naunyn Schmiedebergs Arch Pharmacol. 2023. PMID: 36656353 Review.
Mangiferin (1,3,6,7-tetrahydroxy-2-[3,4,5-trihydroxy-6-(hydroxymethyl) oxan-2-yl] xanthen-9-one) is a bioactive component derived primarily from the mango tree. ...This study assessed and explained the important medical properties of mangiferin available in publishe
Mangiferin (1,3,6,7-tetrahydroxy-2-[3,4,5-trihydroxy-6-(hydroxymethyl) oxan-2-yl] xanthen-9-one) is a bioactive component derived pri
Mangiferin: a review of dietary sources, absorption, metabolism, bioavailability, and safety.
Mei S, Perumal M, Battino M, Kitts DD, Xiao J, Ma H, Chen X. Mei S, et al. Crit Rev Food Sci Nutr. 2023;63(18):3046-3064. doi: 10.1080/10408398.2021.1983767. Epub 2021 Oct 4. Crit Rev Food Sci Nutr. 2023. PMID: 34606395 Review.
However, the low bioavailability of mangiferin is a major limitation for establishing efficacy for use. ...Recent research has led to the development of novel technologies to encapsulate mangiferin in nano/microparticle carrier systems as well as generate mangife
However, the low bioavailability of mangiferin is a major limitation for establishing efficacy for use. ...Recent research has led to …
Mangiferin: An effective therapeutic agent against several disorders (Review).
Du S, Liu H, Lei T, Xie X, Wang H, He X, Tong R, Wang Y. Du S, et al. Mol Med Rep. 2018 Dec;18(6):4775-4786. doi: 10.3892/mmr.2018.9529. Epub 2018 Oct 2. Mol Med Rep. 2018. PMID: 30280187 Review.
However, low solubility, mucosal permeability and bioavailability restrict the development of mangiferin as a clinical therapeutic, and chemical and physical modification is required to expand its application. This review comprehensively analyzed and collectively summarize …
However, low solubility, mucosal permeability and bioavailability restrict the development of mangiferin as a clinical therapeutic, a …
Mangiferin: a natural miracle bioactive compound against lifestyle related disorders.
Imran M, Arshad MS, Butt MS, Kwon JH, Arshad MU, Sultan MT. Imran M, et al. Lipids Health Dis. 2017 May 2;16(1):84. doi: 10.1186/s12944-017-0449-y. Lipids Health Dis. 2017. PMID: 28464819 Free PMC article. Review.
The current review article is an attempt to explain the therapeutic potential of mangiferin, a bioactive compound of the mango, against lifestyle-related disorders. ...This review summarizes the literature pertaining to mangiferin and its associated health claims... …
The current review article is an attempt to explain the therapeutic potential of mangiferin, a bioactive compound of the mango, again …
Renoprotective Effects of Mangiferin: Pharmacological Advances and Future Perspectives.
Akter S, Moni A, Faisal GM, Uddin MR, Jahan N, Hannan MA, Rahman A, Uddin MJ. Akter S, et al. Int J Environ Res Public Health. 2022 Feb 7;19(3):1864. doi: 10.3390/ijerph19031864. Int J Environ Res Public Health. 2022. PMID: 35162887 Free PMC article. Review.
The main objective of this review is to update the renoprotective potentials of mangiferin with underlying molecular pharmacology and to highlight the recent development of mangiferin-based therapeutics toward kidney problems. ...Although mangiferin-loaded na …
The main objective of this review is to update the renoprotective potentials of mangiferin with underlying molecular pharmacology and …
Mangiferin: a promising anticancer bioactive.
Khurana RK, Kaur R, Lohan S, Singh KK, Singh B. Khurana RK, et al. Pharm Pat Anal. 2016 May;5(3):169-81. doi: 10.4155/ppa-2016-0003. Epub 2016 Apr 18. Pharm Pat Anal. 2016. PMID: 27088726 Review.
These polyphenols of mangiferin exhibit antioxidant properties and tend to decrease the oxygen-free radicals, thereby reducing the DNA damage. ...Considering it as promising polyphenol, this paper would also summarize the diverse molecular targets of mangiferin....
These polyphenols of mangiferin exhibit antioxidant properties and tend to decrease the oxygen-free radicals, thereby reducing the DN …
1,130 results