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Results: 1 to 20 of 65

1.

STRA6 is critical for cellular vitamin A uptake and homeostasis.

Amengual J, Zhang N, Kemerer M, Maeda T, Palczewski K, Von Lintig J.

Hum Mol Genet. 2014 May 22. pii: ddu258. [Epub ahead of print]

PMID:
24852372
[PubMed - as supplied by publisher]
2.

All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.

Sawada O, Perusek L, Kohno H, Howell SJ, Maeda A, Matsuyama S, Maeda T.

Exp Eye Res. 2014 Jun;123:27-36. doi: 10.1016/j.exer.2014.04.003. Epub 2014 Apr 12.

PMID:
24726920
[PubMed - indexed for MEDLINE]
3.

Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice.

Maeda A, Palczewska G, Golczak M, Kohno H, Dong Z, Maeda T, Palczewski K.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1428-37. doi: 10.1073/pnas.1317986111. Epub 2014 Mar 24.

PMID:
24706832
[PubMed - indexed for MEDLINE]
4.

CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.

Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A.

J Immunol. 2014 Apr 15;192(8):3816-27. doi: 10.4049/jimmunol.1301738. Epub 2014 Mar 17.

PMID:
24639355
[PubMed - indexed for MEDLINE]
5.

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration.

Chen Y, Palczewska G, Mustafi D, Golczak M, Dong Z, Sawada O, Maeda T, Maeda A, Palczewski K.

J Clin Invest. 2013 Dec 2;123(12):5119-34. doi: 10.1172/JCI69076. Epub 2013 Nov 15.

PMID:
24231350
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo.

Maeda T, Lee MJ, Palczewska G, Marsili S, Tesar PJ, Palczewski K, Takahashi M, Maeda A.

J Biol Chem. 2013 Nov 29;288(48):34484-93. doi: 10.1074/jbc.M113.518571. Epub 2013 Oct 15.

PMID:
24129572
[PubMed - indexed for MEDLINE]
7.

Vitamin A derivatives as treatment options for retinal degenerative diseases.

Perusek L, Maeda T.

Nutrients. 2013 Jul 12;5(7):2646-66. doi: 10.3390/nu5072646. Review.

PMID:
23857173
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.

Najm FJ, Lager AM, Zaremba A, Wyatt K, Caprariello AV, Factor DC, Karl RT, Maeda T, Miller RH, Tesar PJ.

Nat Biotechnol. 2013 May;31(5):426-33. doi: 10.1038/nbt.2561. Epub 2013 Apr 14.

PMID:
23584611
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.

Kohno H, Chen Y, Kevany BM, Pearlman E, Miyagi M, Maeda T, Palczewski K, Maeda A.

J Biol Chem. 2013 May 24;288(21):15326-41. doi: 10.1074/jbc.M112.448712. Epub 2013 Apr 9.

PMID:
23572532
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Evolutionarily conserved long intergenic non-coding RNAs in the eye.

Mustafi D, Kevany BM, Bai X, Maeda T, Sears JE, Khalil AM, Palczewski K.

Hum Mol Genet. 2013 Aug 1;22(15):2992-3002. doi: 10.1093/hmg/ddt156. Epub 2013 Apr 4.

PMID:
23562822
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Autophagy protects the retina from light-induced degeneration.

Chen Y, Sawada O, Kohno H, Le YZ, Subauste C, Maeda T, Maeda A.

J Biol Chem. 2013 Mar 15;288(11):7506-18. doi: 10.1074/jbc.M112.439935. Epub 2013 Jan 22.

PMID:
23341467
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles.

Maeda T, Dong Z, Jin H, Sawada O, Gao S, Utkhede D, Monk W, Palczewska G, Palczewski K.

Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):455-66. doi: 10.1167/iovs.12-11152.

PMID:
23249702
[PubMed - indexed for MEDLINE]
Free Article
13.

Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization.

Zhang N, Kolesnikov AV, Jastrzebska B, Mustafi D, Sawada O, Maeda T, Genoud C, Engel A, Kefalov VJ, Palczewski K.

J Clin Invest. 2013 Jan 2;123(1):121-37. doi: 10.1172/JCI66176. Epub 2012 Dec 10.

PMID:
23221340
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids.

Gao SQ, Maeda T, Okano K, Palczewski K.

Invest Ophthalmol Vis Sci. 2012 Sep 19;53(10):6314-23.

PMID:
22918645
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Inflammatory priming predisposes mice to age-related retinal degeneration.

Mustafi D, Maeda T, Kohno H, Nadeau JH, Palczewski K.

J Clin Invest. 2012 Aug 1;122(8):2989-3001. doi: 10.1172/JCI64427. Epub 2012 Jul 17.

PMID:
22797304
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Retinal photodamage mediated by all-trans-retinal.

Maeda T, Golczak M, Maeda A.

Photochem Photobiol. 2012 Nov-Dec;88(6):1309-19. doi: 10.1111/j.1751-1097.2012.01143.x. Epub 2012 Apr 24. Review.

PMID:
22428905
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage.

Okano K, Maeda A, Chen Y, Chauhan V, Tang J, Palczewska G, Sakai T, Tsuneoka H, Palczewski K, Maeda T.

J Neurochem. 2012 Apr;121(1):146-56. doi: 10.1111/j.1471-4159.2012.07647.x. Epub 2012 Feb 9.

PMID:
22220722
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Primary amines protect against retinal degeneration in mouse models of retinopathies.

Maeda A, Golczak M, Chen Y, Okano K, Kohno H, Shiose S, Ishikawa K, Harte W, Palczewska G, Maeda T, Palczewski K.

Nat Chem Biol. 2011 Dec 25;8(2):170-8. doi: 10.1038/nchembio.759.

PMID:
22198730
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.

Chen Y, Okano K, Maeda T, Chauhan V, Golczak M, Maeda A, Palczewski K.

J Biol Chem. 2012 Feb 10;287(7):5059-69. doi: 10.1074/jbc.M111.315432. Epub 2011 Dec 19.

PMID:
22184108
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis.

Maeda T, Perusek L, Amengual J, Babino D, Palczewski K, von Lintig J.

Mol Pharmacol. 2011 Nov;80(5):943-52. doi: 10.1124/mol.111.074732. Epub 2011 Aug 23.

PMID:
21862692
[PubMed - indexed for MEDLINE]
Free PMC Article

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