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Results: 1 to 20 of 75


A signaling network stimulated by β2 integrin promotes the polarization of lytic granules in cytotoxic cells.

Zhang M, March ME, Lane WS, Long EO.

Sci Signal. 2014 Oct 7;7(346):ra96. doi: 10.1126/scisignal.2005629.


Found: a cellular activating ligand for NKp44.

Rajagopalan S, Long EO.

Blood. 2013 Oct 24;122(17):2921-2. doi: 10.1182/blood-2013-09-523696.


Cutting edge: NK cell licensing modulates adhesion to target cells.

Thomas LM, Peterson ME, Long EO.

J Immunol. 2013 Oct 15;191(8):3981-5. doi: 10.4049/jimmunol.1301159. Epub 2013 Sep 13.


A positive role for senescence in reproduction?

Rajagopalan S, Long EO.

Aging (Albany NY). 2013 Feb;5(2):96-7. No abstract available.


Controlling natural killer cell responses: integration of signals for activation and inhibition.

Long EO, Kim HS, Liu D, Peterson ME, Rajagopalan S.

Annu Rev Immunol. 2013;31:227-58. doi: 10.1146/annurev-immunol-020711-075005. Review.


Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling.

Rajagopalan S, Long EO.

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20596-601. doi: 10.1073/pnas.1208248109. Epub 2012 Nov 26.


KIR2DL4 (CD158d): An activation receptor for HLA-G.

Rajagopalan S, Long EO.

Front Immunol. 2012 Aug 20;3:258. doi: 10.3389/fimmu.2012.00258. eCollection 2012.


The adaptor protein Crk controls activation and inhibition of natural killer cells.

Liu D, Peterson ME, Long EO.

Immunity. 2012 Apr 20;36(4):600-11. doi: 10.1016/j.immuni.2012.03.007. Epub 2012 Mar 29.


Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.

Ombrello MJ, Remmers EF, Sun G, Freeman AF, Datta S, Torabi-Parizi P, Subramanian N, Bunney TD, Baxendale RW, Martins MS, Romberg N, Komarow H, Aksentijevich I, Kim HS, Ho J, Cruse G, Jung MY, Gilfillan AM, Metcalfe DD, Nelson C, O'Brien M, Wisch L, Stone K, Douek DC, Gandhi C, Wanderer AA, Lee H, Nelson SF, Shianna KV, Cirulli ET, Goldstein DB, Long EO, Moir S, Meffre E, Holland SM, Kastner DL, Katan M, Hoffman HM, Milner JD.

N Engl J Med. 2012 Jan 26;366(4):330-8. doi: 10.1056/NEJMoa1102140. Epub 2012 Jan 11.


Palmitoylation of MICA, a ligand for NKG2D, mediates its recruitment to membrane microdomains and promotes its shedding.

Agüera-González S, Gross CC, Fernández-Messina L, Ashiru O, Esteso G, Hang HC, Reyburn HT, Long EO, Valés-Gómez M.

Eur J Immunol. 2011 Dec;41(12):3667-76. doi: 10.1002/eji.201141645. Epub 2011 Nov 3.


ICAM-1: getting a grip on leukocyte adhesion.

Long EO.

J Immunol. 2011 May 1;186(9):5021-3. doi: 10.4049/jimmunol.1100646. Review. No abstract available.


Two modes of lytic granule fusion during degranulation by natural killer cells.

Liu D, Martina JA, Wu XS, Hammer JA 3rd, Long EO.

Immunol Cell Biol. 2011 Aug;89(6):728-38. doi: 10.1038/icb.2010.167. Epub 2011 Apr 12.


Cutting edge: NKG2D-dependent cytotoxicity is controlled by ligand distribution in the target cell membrane.

Martinez E, Brzostowski JA, Long EO, Gross CC.

J Immunol. 2011 May 15;186(10):5538-42. doi: 10.4049/jimmunol.1002254. Epub 2011 Apr 4.


β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells.

March ME, Long EO.

J Immunol. 2011 Mar 1;186(5):2998-3005. doi: 10.4049/jimmunol.1002438. Epub 2011 Jan 26.


Distinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cells.

Liu D, Meckel T, Long EO.

PLoS One. 2010 Sep 21;5(9):e12870. doi: 10.1371/journal.pone.0012870.


Lytic granule polarization, rather than degranulation, is the preferred target of inhibitory receptors in NK cells.

Das A, Long EO.

J Immunol. 2010 Oct 15;185(8):4698-704. doi: 10.4049/jimmunol.1001220. Epub 2010 Sep 10.


Signal transduction during activation and inhibition of natural killer cells.

Watzl C, Long EO.

Curr Protoc Immunol. 2010 Aug;Chapter 11:Unit 11.9B. doi: 10.1002/0471142735.im1109bs90. Review.


Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.

Gross CC, Brzostowski JA, Liu D, Long EO.

J Immunol. 2010 Sep 1;185(5):2918-26. doi: 10.4049/jimmunol.1000761. Epub 2010 Jul 30.


Cytotoxic immunological synapses.

Dustin ML, Long EO.

Immunol Rev. 2010 May;235(1):24-34. doi: 10.1111/j.0105-2896.2010.00904.x. Review.

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