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Results: 1 to 20 of 171

1.

Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling in Absence of Serum.

Teo AK, Valdez IA, Dirice E, Kulkarni RN.

Stem Cell Reports. 2014 Jun 12;3(1):5-14. doi: 10.1016/j.stemcr.2014.05.007. eCollection 2014 Jul 8.

PMID:
25068117
[PubMed]
Free PMC Article
2.

Disruption of Protein-Tyrosine Phosphatase 1B Expression in the Pancreas Affects β-Cell Function.

Liu S, Xi Y, Bettaieb A, Matsuo K, Matsuo I, Kulkarni RN, Haj FG.

Endocrinology. 2014 Sep;155(9):3329-38. doi: 10.1210/en.2013-2004. Epub 2014 Jun 23.

PMID:
24956127
[PubMed - in process]
3.

Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells.

Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2319-28. doi: 10.1073/pnas.1323066111. Epub 2014 May 19.

PMID:
24843127
[PubMed - indexed for MEDLINE]
4.

Palmitate Induces mRNA Translation and Increases ER Protein Load in Islet β Cells via Activation of the Mammalian Target of Rapamycin Pathway.

Hatanaka M, Maier B, Sims EK, Templin AT, Kulkarni RN, Evans-Molina C, Mirmira RG.

Diabetes. 2014 May 16. pii: DB_140105. [Epub ahead of print]

PMID:
24834975
[PubMed - as supplied by publisher]
5.

The regulation of pre- and post-maturational plasticity of mammalian islet cell mass.

Mezza T, Kulkarni RN.

Diabetologia. 2014 Jul;57(7):1291-303. doi: 10.1007/s00125-014-3251-7. Epub 2014 May 14.

PMID:
24824733
[PubMed - in process]
6.

Post renal transplant posterior reversible encephalopathy syndrome.

Kulkarni RN, Saxen SK, Hartalkar A.

J Assoc Physicians India. 2013 Oct;61(10):743-5.

PMID:
24772733
[PubMed - indexed for MEDLINE]
7.

Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.

Bernal-Mizrachi E, Kulkarni RN, Scott DK, Mauvais-Jarvis F, Stewart AF, Garcia-Ocaña A.

Diabetes. 2014 Mar;63(3):819-31. doi: 10.2337/db13-1146. Review.

PMID:
24556859
[PubMed - indexed for MEDLINE]
Free Article
8.

The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.

Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CW, Alonso LC, Myers MG Jr, Jonas JC, Poitout V, Kulkarni RN, Mauvais-Jarvis F.

PLoS One. 2014 Feb 3;9(2):e87941. doi: 10.1371/journal.pone.0087941. eCollection 2014.

PMID:
24498408
[PubMed - in process]
Free PMC Article
9.

IL-6 alters osteocyte signaling toward osteoblasts but not osteoclasts.

Bakker AD, Kulkarni RN, Klein-Nulend J, Lems WF.

J Dent Res. 2014 Apr;93(4):394-9. doi: 10.1177/0022034514522485. Epub 2014 Feb 3.

PMID:
24492932
[PubMed - indexed for MEDLINE]
10.

p85α deficiency protects β-cells from endoplasmic reticulum stress-induced apoptosis.

Winnay JN, Dirice E, Liew CW, Kulkarni RN, Kahn CR.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1192-7. doi: 10.1073/pnas.1322564111. Epub 2014 Jan 6.

PMID:
24395790
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Insulin resistance alters islet morphology in nondiabetic humans.

Mezza T, Muscogiuri G, Sorice GP, Clemente G, Hu J, Pontecorvi A, Holst JJ, Giaccari A, Kulkarni RN.

Diabetes. 2014 Mar;63(3):994-1007. doi: 10.2337/db13-1013. Epub 2013 Nov 11.

PMID:
24215793
[PubMed - indexed for MEDLINE]
Free Article
12.

Soluble factors secreted by T cells promote β-cell proliferation.

Dirice E, Kahraman S, Jiang W, El Ouaamari A, De Jesus DF, Teo AK, Hu J, Kawamori D, Gaglia JL, Mathis D, Kulkarni RN.

Diabetes. 2014 Jan;63(1):188-202. doi: 10.2337/db13-0204. Epub 2013 Oct 2.

PMID:
24089508
[PubMed - indexed for MEDLINE]
Free Article
13.

Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid.

Ræder H, McAllister FE, Tjora E, Bhatt S, Haldorsen I, Hu J, Willems SM, Vesterhus M, El Ouaamari A, Liu M, Ræder MB, Immervoll H, Hoem D, Dimcevski G, Njølstad PR, Molven A, Gygi SP, Kulkarni RN.

Diabetes. 2014 Jan;63(1):259-69. doi: 10.2337/db13-1012. Epub 2013 Sep 23.

PMID:
24062244
[PubMed - indexed for MEDLINE]
Free Article
14.

New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism.

Teo AK, Wagers AJ, Kulkarni RN.

Cell Metab. 2013 Dec 3;18(6):775-91. doi: 10.1016/j.cmet.2013.08.010. Epub 2013 Sep 12. Review.

PMID:
24035588
[PubMed - indexed for MEDLINE]
15.

GCK-MODY diabetes as a protein misfolding disease: the mutation R275C promotes protein misfolding, self-association and cellular degradation.

Negahdar M, Aukrust I, Molnes J, Solheim MH, Johansson BB, Sagen JV, Dahl-Jørgensen K, Kulkarni RN, Søvik O, Flatmark T, Njølstad PR, Bjørkhaug L.

Mol Cell Endocrinol. 2014 Jan 25;382(1):55-65. doi: 10.1016/j.mce.2013.08.020. Epub 2013 Aug 31.

PMID:
24001579
[PubMed - indexed for MEDLINE]
16.

Mechanical vibration inhibits osteoclast formation by reducing DC-STAMP receptor expression in osteoclast precursor cells.

Kulkarni RN, Voglewede PA, Liu D.

Bone. 2013 Dec;57(2):493-8. doi: 10.1016/j.bone.2013.08.020. Epub 2013 Aug 28.

PMID:
23994170
[PubMed - indexed for MEDLINE]
17.

Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle.

Koh HJ, Toyoda T, Didesch MM, Lee MY, Sleeman MW, Kulkarni RN, Musi N, Hirshman MF, Goodyear LJ.

Nat Commun. 2013;4:1871. doi: 10.1038/ncomms2851.

PMID:
23695665
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young).

Ræder H, Vesterhus M, El Ouaamari A, Paulo JA, McAllister FE, Liew CW, Hu J, Kawamori D, Molven A, Gygi SP, Njølstad PR, Kahn CR, Kulkarni RN.

PLoS One. 2013;8(4):e60229. doi: 10.1371/journal.pone.0060229. Epub 2013 Apr 2.

PMID:
23565203
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function.

Akiyama M, Liew CW, Lu S, Hu J, Martinez R, Hambro B, Kennedy RT, Kulkarni RN.

Diabetes. 2013 Jul;62(7):2439-49. doi: 10.2337/db12-1747. Epub 2013 Mar 14.

PMID:
23493568
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states.

El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian WJ, Wagers AJ, Kulkarni RN.

Cell Rep. 2013 Feb 21;3(2):401-10. doi: 10.1016/j.celrep.2013.01.007. Epub 2013 Jan 31. Erratum in: Cell Rep. 2013 Mar 28;3(3):969.

PMID:
23375376
[PubMed - indexed for MEDLINE]
Free PMC Article

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