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Items: 1 to 20 of 199

1.

Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation.

Valdez IA, Dirice E, Gupta MK, Shirakawa J, Teo AK, Kulkarni RN.

Cell Rep. 2016 Apr 19;15(3):460-70. doi: 10.1016/j.celrep.2016.03.036. Epub 2016 Apr 7.

2.

The Hypoglycemic Phenotype is Islet Cell-Autonomous in Short-chain Hydroxyacyl-CoA Dehydrogenase (SCHAD) Deficient Mice.

Molven A, Hollister-Lock J, Hu J, Martinez R, Njølstad PR, Liew CW, Weir G, Kulkarni RN.

Diabetes. 2016 Mar 7. pii: db151475. [Epub ahead of print]

PMID:
26953163
3.

Inhibition of DYRK1A stimulates human beta-cell proliferation.

Dirice E, Walpita D, Vetere A, Meier BC, Kahraman S, Hu J, Dančík V, Burns SM, Gilbert TJ, Olson DE, Clemons PA, Kulkarni RN, Wagner BK.

Diabetes. 2016 Mar 7. pii: db151127. [Epub ahead of print]

PMID:
26953159
4.

Inhibition of TGF-beta signaling promotes human pancreatic beta cell replication.

Dhawan S, Dirice E, Kulkarni RN, Bhushan A.

Diabetes. 2016 Mar 2. pii: db151331. [Epub ahead of print]

PMID:
26936960
5.

Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.

Teo AK, Lau HH, Valdez IA, Dirice E, Tjora E, Raeder H, Kulkarni RN.

Stem Cell Reports. 2016 Mar 8;6(3):357-67. doi: 10.1016/j.stemcr.2016.01.007. Epub 2016 Feb 11.

6.

Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas.

Singhal G, Fisher FM, Chee MJ, Tan TG, El Ouaamari A, Adams AC, Najarian R, Kulkarni RN, Benoist C, Flier JS, Maratos-Flier E.

PLoS One. 2016 Feb 12;11(2):e0148252. doi: 10.1371/journal.pone.0148252. eCollection 2016.

7.

Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome.

Khor EC, Fanshawe B, Qi Y, Zolotukhin S, Kulkarni RN, Enriquez RF, Purtell L, Lee NJ, Wee NK, Croucher PI, Campbell L, Herzog H, Baldock PA.

PLoS One. 2016 Jan 29;11(1):e0148155. doi: 10.1371/journal.pone.0148155. eCollection 2016.

8.

Harnessing immune cells to enhance β-cell mass in type 1 diabetes.

Dirice E, Kulkarni RN.

J Investig Med. 2016 Jan;64(1):14-20. doi: 10.1136/jim-d-15-00196.

PMID:
26755809
9.

The y6 receptor suppresses bone resorption and stimulates bone formation in mice via a suprachiasmatic nucleus relay.

Khor EC, Yulyaningsih E, Driessler F, Kovaĉić N, Wee NK, Kulkarni RN, Lee NJ, Enriquez RF, Xu J, Zhang L, Herzog H, Baldock PA.

Bone. 2016 Mar;84:139-47. doi: 10.1016/j.bone.2015.12.011. Epub 2015 Dec 22.

PMID:
26721736
10.

SerpinB1 Promotes Pancreatic β Cell Proliferation.

El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN.

Cell Metab. 2016 Jan 12;23(1):194-205. doi: 10.1016/j.cmet.2015.12.001. Epub 2015 Dec 15.

PMID:
26701651
11.

β-Cell Glucose Sensitivity Is Linked to Insulin/Glucagon Bihormonal Cells in Nondiabetic Humans.

Mezza T, Sorice GP, Conte C, Sun VA, Cefalo CM, Moffa S, Pontecorvi A, Mari A, Kulkarni RN, Giaccari A.

J Clin Endocrinol Metab. 2016 Feb;101(2):470-5. doi: 10.1210/jc.2015-2802. Epub 2015 Dec 9.

PMID:
26649619
12.

Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2).

Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, Jung DY, Lee Y, Kitamura T, Ergun S, Kulkarni RN, Kim JK, Giovannucci DR, Najjar SM.

J Biol Chem. 2016 Jan 8;291(2):980-8. doi: 10.1074/jbc.M115.692582. Epub 2015 Nov 19.

PMID:
26586918
13.

The brain in bone and fuel metabolism.

Wee NK, Kulkarni RN, Horsnell H, Baldock PA.

Bone. 2016 Jan;82:56-63. doi: 10.1016/j.bone.2015.10.020. Epub 2015 Nov 9. Review.

PMID:
26545334
14.

Neuronal control of bone and muscle.

Houweling P, Kulkarni RN, Baldock PA.

Bone. 2015 Nov;80:95-100. doi: 10.1016/j.bone.2015.05.006. Review.

PMID:
26453499
15.

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools.

Teo AK, Gupta MK, Doria A, Kulkarni RN.

Mol Metab. 2015 Jun 20;4(9):593-604. doi: 10.1016/j.molmet.2015.06.006. eCollection 2015 Sep. Review.

16.

Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.

Lee YJ, Liu C, Liao M, Sukhova GK, Shirakawa J, Abdennour M, Iamarene K, Andre S, Inouye K, Clement K, Kulkarni RN, Banks AS, Libby P, Shi GP.

Endocrinology. 2015 Nov;156(11):4047-58. doi: 10.1210/en.2015-1184. Epub 2015 Aug 21.

PMID:
26295369
17.

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts.

Gupta MK, Teo AK, Rao TN, Bhatt S, Kleinridders A, Shirakawa J, Takatani T, Hu J, De Jesus DF, Windmueller R, Wagers AJ, Kulkarni RN.

Stem Cells Transl Med. 2015 Oct;4(10):1101-8. doi: 10.5966/sctm.2014-0217. Epub 2015 Aug 7.

18.

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.

Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, Takatani T, Keenan HA, Smith RD, Church G, Weiss R, Wagers AJ, Qian WJ, King GL, Kulkarni RN.

Cell Metab. 2015 Aug 4;22(2):239-52. doi: 10.1016/j.cmet.2015.07.015.

19.

Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics.

El Ouaamari A, Zhou JY, Liew CW, Shirakawa J, Dirice E, Gedeon N, Kahraman S, De Jesus DF, Bhatt S, Kim JS, Clauss TR, Camp DG 2nd, Smith RD, Qian WJ, Kulkarni RN.

J Proteome Res. 2015 Aug 7;14(8):3111-22. doi: 10.1021/acs.jproteome.5b00587. Epub 2015 Jul 30.

PMID:
26151086
20.

Human β-cell proliferation and intracellular signaling: part 3.

Stewart AF, Hussain MA, García-Ocaña A, Vasavada RC, Bhushan A, Bernal-Mizrachi E, Kulkarni RN.

Diabetes. 2015 Jun;64(6):1872-85. doi: 10.2337/db14-1843. Review.

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