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Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcino-Embryonic Antigen-related Cell Adhesion Molecule 2.

Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, Jung DY, Lee Y, Kitamura T, Ergun S, Kulkarni RN, Kim JK, Giovannucci DR, Najjar SM.

J Biol Chem. 2015 Nov 19. pii: jbc.M115.692582. [Epub ahead of print]


The brain in bone and fuel metabolism.

Wee NK, Kulkarni RN, Horsnell H, Baldock PA.

Bone. 2015 Nov 5. pii: S8756-3282(15)00393-2. doi: 10.1016/j.bone.2015.10.020. [Epub ahead of print] Review.


Neuronal control of bone and muscle.

Houweling P, Kulkarni RN, Baldock PA.

Bone. 2015 Nov;80:95-100. doi: 10.1016/j.bone.2015.05.006. Review.


Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools.

Teo AK, Gupta MK, Doria A, Kulkarni RN.

Mol Metab. 2015 Jun 20;4(9):593-604. doi: 10.1016/j.molmet.2015.06.006. eCollection 2015 Sep. Review.


Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.

Lee YJ, Liu C, Liao M, Sukhova GK, Shirakawa J, Abdennour M, Iamarene K, Andre S, Inouye K, Clement K, Kulkarni RN, Banks AS, Libby P, Shi GP.

Endocrinology. 2015 Nov;156(11):4047-58. doi: 10.1210/en.2015-1184. Epub 2015 Aug 21.


Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts.

Gupta MK, Teo AK, Rao TN, Bhatt S, Kleinridders A, Shirakawa J, Takatani T, Hu J, De Jesus DF, Windmueller R, Wagers AJ, Kulkarni RN.

Stem Cells Transl Med. 2015 Oct;4(10):1101-8. doi: 10.5966/sctm.2014-0217. Epub 2015 Aug 7.


Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.

Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, Takatani T, Keenan HA, Smith RD, Church G, Weiss R, Wagers AJ, Qian WJ, King GL, Kulkarni RN.

Cell Metab. 2015 Aug 4;22(2):239-52. doi: 10.1016/j.cmet.2015.07.015.


Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics.

El Ouaamari A, Zhou JY, Liew CW, Shirakawa J, Dirice E, Gedeon N, Kahraman S, De Jesus DF, Bhatt S, Kim JS, Clauss TR, Camp DG 2nd, Smith RD, Qian WJ, Kulkarni RN.

J Proteome Res. 2015 Aug 7;14(8):3111-22. doi: 10.1021/acs.jproteome.5b00587. Epub 2015 Jul 30.


Human β-cell proliferation and intracellular signaling: part 3.

Stewart AF, Hussain MA, García-Ocaña A, Vasavada RC, Bhushan A, Bernal-Mizrachi E, Kulkarni RN.

Diabetes. 2015 Jun;64(6):1872-85. doi: 10.2337/db14-1843. Review.


Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance.

Al-Share QY, DeAngelis AM, Lester SG, Bowman TA, Ramakrishnan SK, Abdallah SL, Russo L, Patel PR, Kaw MK, Raphael CK, Kim AJ, Heinrich G, Lee AD, Kim JK, Kulkarni RN, Philbrick WM, Najjar SM.

Diabetes. 2015 Aug;64(8):2780-90. doi: 10.2337/db14-1772. Epub 2015 May 13.


High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice.

Rao TN, Marks-Bluth J, Sullivan J, Gupta MK, Chandrakanthan V, Fitch SR, Ottersbach K, Jang YC, Piao X, Kulkarni RN, Serwold T, Pimanda JE, Wagers AJ.

Stem Cell Res. 2015 May;14(3):307-22. doi: 10.1016/j.scr.2015.02.001. Epub 2015 Feb 18.


Cellular stress drives pancreatic plasticity.

Valdez IA, Teo AK, Kulkarni RN.

Sci Transl Med. 2015 Feb 4;7(273):273ps2. doi: 10.1126/scitranslmed.3010577.


Summary of the Keystone islet workshop (April 2014): the increasing demand for human islet availability in diabetes research.

Kulkarni RN, Stewart AF.

Diabetes. 2014 Dec;63(12):3979-81. doi: 10.2337/db14-1303. No abstract available.


The Polycomb protein, Bmi1, regulates insulin sensitivity.

Cannon CE, Titchenell PM, Groff DN, El Ouaamari A, Kulkarni RN, Birnbaum MJ, Stoffers DA.

Mol Metab. 2014 Aug 27;3(8):794-802. doi: 10.1016/j.molmet.2014.08.002. eCollection 2014 Nov.


Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice.

Xi Y, Liu S, Bettaieb A, Matsuo K, Matsuo I, Hosein E, Chahed S, Wiede F, Zhang S, Zhang ZY, Kulkarni RN, Tiganis T, Haj FG.

Diabetologia. 2015 Jan;58(1):122-31. doi: 10.1007/s00125-014-3413-7. Epub 2014 Oct 23.


Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.

Kahraman S, Dirice E, De Jesus DF, Hu J, Kulkarni RN.

Am J Physiol Endocrinol Metab. 2014 Nov 15;307(10):E906-18. doi: 10.1152/ajpendo.00210.2014. Epub 2014 Sep 23.


Epigenetic modifiers of islet function and mass.

De Jesus DF, Kulkarni RN.

Trends Endocrinol Metab. 2014 Dec;25(12):628-36. doi: 10.1016/j.tem.2014.08.006. Epub 2014 Sep 19. Review.


Comparable generation of activin-induced definitive endoderm via additive Wnt or BMP signaling in absence of serum.

Teo AK, Valdez IA, Dirice E, Kulkarni RN.

Stem Cell Reports. 2014 Jun 12;3(1):5-14. doi: 10.1016/j.stemcr.2014.05.007. eCollection 2014 Jul 8.


Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function.

Liu S, Xi Y, Bettaieb A, Matsuo K, Matsuo I, Kulkarni RN, Haj FG.

Endocrinology. 2014 Sep;155(9):3329-38. doi: 10.1210/en.2013-2004. Epub 2014 Jun 23.


Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells.

Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2319-28. doi: 10.1073/pnas.1323066111. Epub 2014 May 19.

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