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Results: 1 to 20 of 221

Select item 235826551.

Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease.

Giraldo M, Lopera F, Siniard AL, Corneveaux JJ, Schrauwen I, Carvajal J, Muñoz C, Ramirez-Restrepo M, Gaiteri C, Myers AJ, Caselli RJ, Kosik KS, Reiman EM, Huentelman MJ.

Neurobiol Aging. 2013 Aug;34(8):2077.e11-8. doi: 10.1016/j.neurobiolaging.2013.02.016. Epub 2013 Apr 9.

PMID:: 23582655; [PubMed - in process]

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Select item 235055412.

MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state.

Smagghe BJ, Stewart AK, Carter MG, Shelton LM, Bernier KJ, Hartman EJ, Calhoun AK, Hatziioannou VM, Lillacci G, Kirk BA, DiNardo BA, Kosik KS, Bamdad C.

PLoS One. 2013;8(3):e58601. doi: 10.1371/journal.pone.0058601. Epub 2013 Mar 7.

PMID:: 23505541; [PubMed - in process]

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Select item 234463513.

Molecular biology: Circles reshape the RNA world.

Kosik KS.

Nature. 2013 Mar 21;495(7441):322-4. doi: 10.1038/nature11956. Epub 2013 Feb 27. No abstract available.

PMID:: 23446351; [PubMed - indexed for MEDLINE]

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Select item 231379494.

Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study.

Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gomez MG, Langois CM, Langbaum JB, Ayutyanont N, Roontiva A, Thiyyagura P, Lee W, Mo H, Lopez L, Moreno S, Acosta-Baena N, Giraldo M, Garcia G, Reiman RA, Huentelman MJ, Kosik KS, Tariot PN, Lopera F, Reiman EM.

Lancet Neurol. 2012 Dec;11(12):1057-65. doi: 10.1016/S1474-4422(12)70227-2. Epub 2012 Nov 6.

PMID:: 23137949; [PubMed - indexed for MEDLINE]

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Select item 231379485.

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study.

Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, Tirado V, Munoz C, Reiman RA, Huentelman MJ, Alexander GE, Langbaum JB, Kosik KS, Tariot PN, Lopera F.

Lancet Neurol. 2012 Dec;11(12):1048-56. doi: 10.1016/S1474-4422(12)70228-4. Epub 2012 Nov 6.

PMID:: 23137948; [PubMed - indexed for MEDLINE]

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Select item 228294676.

Exploratory data from complete genomes of familial alzheimer disease age-at-onset outliers.

Lalli MA, Garcia G, Madrigal L, Arcos-Burgos M, Arcila ML, Kosik KS, Lopera F.

Hum Mutat. 2012 Dec;33(12):1630-4. doi: 10.1002/humu.22167. Epub 2012 Aug 10.

PMID:: 22829467; [PubMed - indexed for MEDLINE]

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Select item 227233597.

Functionalization of a protosynaptic gene expression network.

Conaco C, Bassett DS, Zhou H, Arcila ML, Degnan SM, Degnan BM, Kosik KS.

Proc Natl Acad Sci U S A. 2012 Jun 26;109 Suppl 1:10612-8. doi: 10.1073/pnas.1201890109. Epub 2012 Jun 20.

PMID:: 22723359; [PubMed - indexed for MEDLINE]

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Select item 227102708.

Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease.

Vélez JI, Chandrasekharappa SC, Henao E, Martinez AF, Harper U, Jones M, Solomon BD, Lopez L, Garcia G, Aguirre-Acevedo DC, Acosta-Baena N, Correa JC, Lopera-Gómez CM, Jaramillo-Elorza MC, Rivera D, Kosik KS, Schork NJ, Swanson JM, Lopera F, Arcos-Burgos M.

Mol Psychiatry. 2013 May;18(5):568-75. doi: 10.1038/mp.2012.81. Epub 2012 Jun 19.

PMID:: 22710270; [PubMed - in process]

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Select item 226467469.

Transcriptome profiling of the demosponge Amphimedon queenslandica reveals genome-wide events that accompany major life cycle transitions.

Conaco C, Neveu P, Zhou H, Arcila ML, Degnan SM, Degnan BM, Kosik KS.

BMC Genomics. 2012 May 30;13:209.

PMID:: 22646746; [PubMed - indexed for MEDLINE]

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Select item 2252250910.

Mechanisms of age-related cognitive change and targets for intervention: epigenetics.

Kosik KS, Rapp PR, Raz N, Small SA, Sweatt JD, Tsai LH.

J Gerontol A Biol Sci Med Sci. 2012 Jun;67(7):741-6. doi: 10.1093/gerona/gls110. Epub 2012 Apr 20. Review.

PMID:: 22522509; [PubMed - indexed for MEDLINE]

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Select item 2243488111.

Deep annotation of mouse iso-miR and iso-moR variation.

Zhou H, Arcila ML, Li Z, Lee EJ, Henzler C, Liu J, Rana TM, Kosik KS.

Nucleic Acids Res. 2012 Jul;40(13):5864-75. doi: 10.1093/nar/gks247. Epub 2012 Mar 19.

PMID:: 22434881; [PubMed - indexed for MEDLINE]

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Select item 2197147112.

Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.

Reiman EM, Langbaum JB, Fleisher AS, Caselli RJ, Chen K, Ayutyanont N, Quiroz YT, Kosik KS, Lopera F, Tariot PN.

J Alzheimers Dis. 2011;26 Suppl 3:321-9. doi: 10.3233/JAD-2011-0059. Review.

PMID:: 21971471; [PubMed - indexed for MEDLINE]

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Select item 2193181113.

NMDA mediated contextual conditioning changes miRNA expression.

Kye MJ, Neveu P, Lee YS, Zhou M, Steen JA, Sahin M, Kosik KS, Silva AJ.

PLoS One. 2011;6(9):e24682. doi: 10.1371/journal.pone.0024682. Epub 2011 Sep 12.

PMID:: 21931811; [PubMed - indexed for MEDLINE]

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Select item 2187405114.

Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases.

Papagiannakopoulos T, Friedmann-Morvinski D, Neveu P, Dugas JC, Gill RM, Huillard E, Liu C, Zong H, Rowitch DH, Barres BA, Verma IM, Kosik KS.

Oncogene. 2012 Apr 12;31(15):1884-95. doi: 10.1038/onc.2011.380. Epub 2011 Aug 29.

PMID:: 21874051; [PubMed - indexed for MEDLINE]

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Select item 2159384615.

PhDs: what's left if science abdicates?

Kosik KS.

Nature. 2011 May 19;473(7347):284. doi: 10.1038/473284b. No abstract available.

PMID:: 21593846; [PubMed - indexed for MEDLINE]

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Select item 2151582916.

Identification of piRNAs in the central nervous system.

Lee EJ, Banerjee S, Zhou H, Jammalamadaka A, Arcila M, Manjunath BS, Kosik KS.

RNA. 2011 Jun;17(6):1090-9. doi: 10.1261/rna.2565011. Epub 2011 Apr 22.

PMID:: 21515829; [PubMed - indexed for MEDLINE]

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Select item 2135354517.

Structure-activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors.

Laha JK, Zhang X, Qiao L, Liu M, Chatterjee S, Robinson S, Kosik KS, Cuny GD.

Bioorg Med Chem Lett. 2011 Apr 1;21(7):2098-101. doi: 10.1016/j.bmcl.2011.01.140. Epub 2011 Feb 3.

PMID:: 21353545; [PubMed - indexed for MEDLINE]

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Select item 2111256218.

MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states.

Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M, Park IH, Kim KS, Daley GQ, Kornblum HI, Shraiman BI, Kosik KS.

Cell Stem Cell. 2010 Dec 3;7(6):671-81. doi: 10.1016/j.stem.2010.11.012.

PMID:: 21112562; [PubMed - indexed for MEDLINE]

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Select item 2108564519.

Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology.

Yuraszeck TM, Neveu P, Rodriguez-Fernandez M, Robinson A, Kosik KS, Doyle FJ 3rd.

PLoS Comput Biol. 2010 Nov 11;6(11):e1000997. doi: 10.1371/journal.pcbi.1000997.

PMID:: 21085645; [PubMed - indexed for MEDLINE]

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Select item 2106829420.

MicroRNA regulation of neural stem cells and neurogenesis.

Shi Y, Zhao X, Hsieh J, Wichterle H, Impey S, Banerjee S, Neveu P, Kosik KS.

J Neurosci. 2010 Nov 10;30(45):14931-6. doi: 10.1523/JNEUROSCI.4280-10.2010. Review.

PMID:: 21068294; [PubMed - indexed for MEDLINE]

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60 free full-text articles in PubMed Central

MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state. [PLoS One. 2013]
MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state.
Smagghe BJ, Stewart AK, Carter MG, Shelton LM, Bernier KJ, Hartman EJ, Calhoun AK, Hatziioannou VM, Lillacci G, Kirk BA, et al. PLoS One. 2013; 8(3):e58601. Epub 2013 Mar 7.
Functionalization of a protosynaptic gene expression network. [Proc Natl Acad Sci U S A. 2012]
Functionalization of a protosynaptic gene expression network.
Conaco C, Bassett DS, Zhou H, Arcila ML, Degnan SM, Degnan BM, Kosik KS. Proc Natl Acad Sci U S A. 2012 Jun 26; 109 Suppl 1:10612-8. Epub 2012 Jun 20.
Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease. [Mol Psychiatry. 2013]
Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease.
Vélez JI, Chandrasekharappa SC, Henao E, Martinez AF, Harper U, Jones M, Solomon BD, Lopez L, Garcia G, Aguirre-Acevedo DC, et al. Mol Psychiatry. 2013 May; 18(5):568-75. Epub 2012 Jun 19.