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Items: 1 to 20 of 688

1.

Unraveling the Paradox of Selective Insulin Resistance in the Liver: the Brain-Liver Connection.

Ferris HA, Kahn CR.

Diabetes. 2016 Jun;65(6):1481-3. doi: 10.2337/dbi16-0010. No abstract available.

PMID:
27222392
2.

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.

Boucher J, Softic S, El Ouaamari A, Krumpoch MT, Kleinridders A, Kulkarni RN, O'Neill BT, Kahn CR.

Diabetes. 2016 May 13. pii: db160212. [Epub ahead of print]

PMID:
27207537
3.

Lipodystrophy Due to Adipose Tissue Specific Insulin Receptor Knockout Results in Progressive NAFLD.

Softic S, Boucher J, Solheim MH, Fujisaka S, Haering MF, Homan EP, Winnay J, Perez-Atayde AR, Kahn CR.

Diabetes. 2016 May 10. pii: db160213. [Epub ahead of print]

PMID:
27207510
4.

PI3-kinase mutation linked to insulin and growth factor resistance in vivo.

Winnay JN, Solheim MH, Dirice E, Sakaguchi M, Noh HL, Kang HJ, Takahashi H, Chudasama KK, Kim JK, Molven A, Kahn CR, Njølstad PR.

J Clin Invest. 2016 Apr 1;126(4):1401-12. doi: 10.1172/JCI84005. Epub 2016 Mar 14.

PMID:
26974159
5.

Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function.

Burkart AM, Tan K, Warren L, Iovino S, Hughes KJ, Kahn CR, Patti ME.

Sci Rep. 2016 Mar 7;6:22788. doi: 10.1038/srep22788.

6.

Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity.

Viana-Huete V, Guillén C, García-Aguilar A, García G, Fernández S, Kahn CR, Benito M.

Endocrinology. 2016 Apr;157(4):1495-511. doi: 10.1210/en.2015-1623. Epub 2016 Feb 24.

PMID:
26910308
7.

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease.

Softic S, Cohen DE, Kahn CR.

Dig Dis Sci. 2016 May;61(5):1282-93. doi: 10.1007/s10620-016-4054-0. Epub 2016 Feb 8. Review.

PMID:
26856717
8.

Myotubes derived from human-induced pluripotent stem cells mirror in vivo insulin resistance.

Iovino S, Burkart AM, Warren L, Patti ME, Kahn CR.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1889-94. doi: 10.1073/pnas.1525665113. Epub 2016 Feb 1.

9.

Dysfunctional Subcutaneous Fat With Reduced Dicer and Brown Adipose Tissue Gene Expression in HIV-Infected Patients.

Torriani M, Srinivasa S, Fitch KV, Thomou T, Wong K, Petrow E, Kahn CR, Cypess AM, Grinspoon SK.

J Clin Endocrinol Metab. 2016 Mar;101(3):1225-34. doi: 10.1210/jc.2015-3993. Epub 2016 Jan 12.

PMID:
26756119
10.

CDK4 is an essential insulin effector in adipocytes.

Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L.

J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14.

11.

Effect of cholesterol reduction on receptor signaling in neurons.

Fukui K, Ferris HA, Kahn CR.

J Biol Chem. 2015 Oct 30;290(44):26383-92. doi: 10.1074/jbc.M115.664367. Epub 2015 Sep 14.

PMID:
26370080
12.

Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism.

Li M, Vienberg SG, Bezy O, O'Neill BT, Kahn CR.

Diabetes. 2015 Dec;64(12):4023-32. doi: 10.2337/db14-1891. Epub 2015 Aug 25.

PMID:
26307588
13.

Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome.

Ussar S, Griffin NW, Bezy O, Fujisaka S, Vienberg S, Softic S, Deng L, Bry L, Gordon JI, Kahn CR.

Cell Metab. 2015 Sep 1;22(3):516-30. doi: 10.1016/j.cmet.2015.07.007. Epub 2015 Aug 20.

PMID:
26299453
14.

Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.

Lee KY, Singh MK, Ussar S, Wetzel P, Hirshman MF, Goodyear LJ, Kispert A, Kahn CR.

Nat Commun. 2015 Aug 24;6:8054. doi: 10.1038/ncomms9054.

15.

Erratum: FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.

O-Sullivan I, Zhang W, Wasserman DH, Liew CW, Liu J, Paik J, DePinho RA, Stolz DB, Kahn CR, Schwartz MW, Unterman TG.

Nat Commun. 2015 Jul 24;6:7861. doi: 10.1038/ncomms8861. No abstract available.

PMID:
26206703
16.

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing.

Wong SL, Demers M, Martinod K, Gallant M, Wang Y, Goldfine AB, Kahn CR, Wagner DD.

Nat Med. 2015 Jul;21(7):815-9. doi: 10.1038/nm.3887. Epub 2015 Jun 15.

17.

Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis.

O'Neill BT, Lauritzen HP, Hirshman MF, Smyth G, Goodyear LJ, Kahn CR.

Cell Rep. 2015 May 26;11(8):1220-35. doi: 10.1016/j.celrep.2015.04.037. Epub 2015 May 14.

18.

FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.

O-Sullivan I, Zhang W, Wasserman DH, Liew CW, Liu J, Paik J, DePinho RA, Stolz DB, Kahn CR, Schwartz MW, Unterman TG.

Nat Commun. 2015 May 12;6:7079. doi: 10.1038/ncomms8079. Erratum in: Nat Commun. 2015;6:7861.

19.

Severe insulin resistance alters metabolism in mesenchymal progenitor cells.

Balhara B, Burkart A, Topcu V, Lee YK, Cowan C, Kahn CR, Patti ME.

Endocrinology. 2015 Jun;156(6):2039-48. doi: 10.1210/en.2014-1403. Epub 2015 Mar 26.

PMID:
25811318
20.

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders.

Kleinridders A, Cai W, Cappellucci L, Ghazarian A, Collins WR, Vienberg SG, Pothos EN, Kahn CR.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3463-8. doi: 10.1073/pnas.1500877112. Epub 2015 Mar 2.

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