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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1807 1
1808 1
1814 1
1815 1
1820 1
1828 1
1831 2
1839 1
1842 1
1845 1
1848 1
1853 1
1867 2
1871 1
1872 5
1875 2
1876 2
1877 3
1878 1
1879 2
1880 2
1881 2
1883 2
1884 3
1885 4
1887 1
1889 1
1890 5
1891 1
1892 1
1894 1
1895 2
1896 5
1897 5
1898 5
1899 6
1900 7
1901 12
1902 3
1903 8
1904 3
1905 11
1906 10
1907 15
1908 18
1909 16
1910 26
1911 36
1912 21
1913 30
1914 45
1915 38
1916 37
1917 45
1918 28
1919 35
1920 48
1921 45
1922 61
1923 55
1924 61
1925 46
1926 68
1927 75
1928 75
1929 70
1930 57
1931 64
1932 86
1933 83
1934 85
1935 79
1936 88
1937 89
1938 94
1939 78
1940 79
1941 99
1942 96
1943 83
1944 92
1945 279
1946 731
1947 878
1948 947
1949 918
1950 1206
1951 1483
1952 1596
1953 1758
1954 2027
1955 2131
1956 2213
1957 2549
1958 2676
1959 2953
1960 3256
1961 3596
1962 3959
1963 4574
1964 5430
1965 5842
1966 6529
1967 7770
1968 8757
1969 9907
1970 10926
1971 12492
1972 14752
1973 15504
1974 16565
1975 29112
1976 31099
1977 30186
1978 30602
1979 32752
1980 35324
1981 36532
1982 39574
1983 45091
1984 48243
1985 51328
1986 53352
1987 55563
1988 58698
1989 67356
1990 70827
1991 73351
1992 76463
1993 78222
1994 81604
1995 85744
1996 89130
1997 91119
1998 96653
1999 100520
2000 108847
2001 114002
2002 119598
2003 127497
2004 137215
2005 148899
2006 159816
2007 168570
2008 176128
2009 183086
2010 197739
2011 212308
2012 226384
2013 238053
2014 247933
2015 255289
2016 259673
2017 267707
2018 278123
2019 290098
2020 324265
2021 349360
2022 347327
2023 329543
2024 119194

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6,411,542 results

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Showing results for is activated
Your search for isoactinate retrieved no results
Exercise training improves motor skill learning via selective activation of mTOR.
Chen K, Zheng Y, Wei JA, Ouyang H, Huang X, Zhang F, Lai CSW, Ren C, So KF, Zhang L. Chen K, et al. Sci Adv. 2019 Jul 3;5(7):eaaw1888. doi: 10.1126/sciadv.aaw1888. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31281888 Free PMC article.
Physical exercise improves learning and memory, but little in vivo evidence has been provided to illustrate the molecular mechanisms. Here, we show that chronic treadmill exercise activates the mechanistic target of rapamycin (mTOR) pathway in mouse motor cortex. .. …
Physical exercise improves learning and memory, but little in vivo evidence has been provided to illustrate the molecular mechanisms. Here, …
The thalamic reticular nucleus is activated by cortical spreading depression in freely moving rats: prevention by acute valproate administration.
Tepe N, Filiz A, Dilekoz E, Akcali D, Sara Y, Charles A, Bolay H. Tepe N, et al. Eur J Neurosci. 2015 Jan;41(1):120-8. doi: 10.1111/ejn.12753. Epub 2014 Oct 18. Eur J Neurosci. 2015. PMID: 25327971
Immunohistochemistry was used to quantify anatomical regions of cellular activation. The effects of acute valproic acid administration on the behavioural parameters and cellular activation were evaluated. ...These findings show that CSD events cause consistent behav …
Immunohistochemistry was used to quantify anatomical regions of cellular activation. The effects of acute valproic acid administratio …
Role of astrocytes in rhythmic motor activity.
Montalant A, Carlsen EMM, Perrier JF. Montalant A, et al. Physiol Rep. 2021 Sep;9(18):e15029. doi: 10.14814/phy2.15029. Physiol Rep. 2021. PMID: 34558208 Free PMC article. Review.
Rhythmic motor activities such as breathing, locomotion, tremor, or mastication are organized by groups of interconnected neurons. ...It is therefore likely that the activation of astrocytes impacts motor control. Here we review recent studies demonstr …
Rhythmic motor activities such as breathing, locomotion, tremor, or mastication are organized by groups of interconnected neur …
The MAP kinase p38 is part of Drosophila melanogaster's circadian clock.
Dusik V, Senthilan PR, Mentzel B, Hartlieb H, Wülbeck C, Yoshii T, Raabe T, Helfrich-Förster C. Dusik V, et al. PLoS Genet. 2014 Aug 21;10(8):e1004565. doi: 10.1371/journal.pgen.1004565. eCollection 2014 Aug. PLoS Genet. 2014. PMID: 25144774 Free PMC article.
Here, we demonstrate by immunocytochemical means that p38 is expressed in Drosophila melanogaster's clock neurons and that it is activated in a clock-dependent manner. Surprisingly, we found that p38 is most active under darkness and, besides its circadian activa …
Here, we demonstrate by immunocytochemical means that p38 is expressed in Drosophila melanogaster's clock neurons and that it is activate …
AMPK and the biochemistry of exercise: implications for human health and disease.
Richter EA, Ruderman NB. Richter EA, et al. Biochem J. 2009 Mar 1;418(2):261-75. doi: 10.1042/BJ20082055. Biochem J. 2009. PMID: 19196246 Free PMC article. Review.
In addition, it improves the metabolic status of rodents with a metabolic syndrome phenotype, as does treatment with AMPK-activating agents; it is therefore tempting to attribute the therapeutic benefits of regular physical activity to activation of AMPK. Her …
In addition, it improves the metabolic status of rodents with a metabolic syndrome phenotype, as does treatment with AMPK-activating …
Is Exercise Really Medicine? An Evolutionary Perspective.
Lieberman DE. Lieberman DE. Curr Sports Med Rep. 2015 Jul-Aug;14(4):313-9. doi: 10.1249/JSR.0000000000000168. Curr Sports Med Rep. 2015. PMID: 26166056
Many lines of evidence indicate that humans evolved to be adapted for regular, moderate amounts of endurance physical activity into late age. However, because energy from food was limited, humans also were selected to avoid unnecessary exertion, and most anatomical and phy …
Many lines of evidence indicate that humans evolved to be adapted for regular, moderate amounts of endurance physical activity into l …
Muscle activity pattern dependent pain development and alleviation.
Sjøgaard G, Søgaard K. Sjøgaard G, et al. J Electromyogr Kinesiol. 2014 Dec;24(6):789-94. doi: 10.1016/j.jelekin.2014.08.005. Epub 2014 Sep 6. J Electromyogr Kinesiol. 2014. PMID: 25245251 Review.
Causal mechanisms include a stereotype recruitment of low threshold motor units (activating type 1 muscle fibers) characterized by a lack of temporal as well as spatial variation in recruitment. In contrast during physical activities at leisure and sport the …
Causal mechanisms include a stereotype recruitment of low threshold motor units (activating type 1 muscle fibers) characterize …
Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes.
Koh HJ, Hirshman MF, He H, Li Y, Manabe Y, Balschi JA, Goodyear LJ. Koh HJ, et al. Biochem J. 2007 May 1;403(3):473-81. doi: 10.1042/BJ20061479. Biochem J. 2007. PMID: 17253964 Free PMC article.
Exercise increases AMPK (AMP-activated protein kinase) activity in human and rat adipocytes, but the underlying molecular mechanisms and functional consequences of this activation are not known. ...Similarly to exercise, adrenaline treatment in vivo increased …
Exercise increases AMPK (AMP-activated protein kinase) activity in human and rat adipocytes, but the underlying molecular mech …
Functional organization of autonomic neural pathways.
Gibbins I. Gibbins I. Organogenesis. 2013 Jul-Sep;9(3):169-75. doi: 10.4161/org.25126. Epub 2013 Jun 6. Organogenesis. 2013. PMID: 23872517 Free PMC article. Review.
Simplistic notions of antagonistic all-or-none activation of sympathetic or parasympathetic pathways are clearly wrong. ...Phasic parasympathetic activity can be seen in lacrimation, salivation or urination. Activity in autonomic motor pathways can be …
Simplistic notions of antagonistic all-or-none activation of sympathetic or parasympathetic pathways are clearly wrong. ...Phasic par …
Binding in voluntary action control.
Nattkemper D, Ziessler M, Frensch PA. Nattkemper D, et al. Neurosci Biobehav Rev. 2010 Jun;34(7):1092-101. doi: 10.1016/j.neubiorev.2009.12.013. Epub 2009 Dec 29. Neurosci Biobehav Rev. 2010. PMID: 20036685 Review.
The last decade has seen a proliferation of empirical studies that seek to understand how the cognitive system links voluntary motor actions with their perceptual effects. A view that has found considerable support in this research is the ideomotor approach to action contr …
The last decade has seen a proliferation of empirical studies that seek to understand how the cognitive system links voluntary motor …
6,411,542 results
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