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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1990 3
1991 4
1992 2
1993 4
1994 7
1995 7
1996 6
1997 3
1998 3
1999 4
2000 5
2001 8
2002 7
2003 8
2004 10
2005 10
2006 16
2007 3
2008 4
2009 15
2010 12
2011 6
2012 4
2013 4
2014 2
2015 5
2016 8
2017 5
2018 3
2019 2
2020 2
2021 2
2022 1
2023 1
2024 1

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178 results

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Page 1
An Integrated Population Pharmacokinetic Analysis for Posaconazole Oral Suspension, Delayed-Release Tablet, and Intravenous Infusion in Healthy Volunteers.
Chen L, Krekels EHJ, Heijnen AR, Knibbe CAJ, Brüggemann RJ. Chen L, et al. Drugs. 2023 Jan;83(1):75-86. doi: 10.1007/s40265-022-01819-8. Epub 2023 Jan 6. Drugs. 2023. PMID: 36607589
Because of the limited and variable absorption of the initially available oral suspension, a delayed-release tablet and intravenous formulation were developed. OBJECTIVE: This study aimed to characterize the pharmacokinetics, including the absolute oral bioavailability, of …
Because of the limited and variable absorption of the initially available oral suspension, a delayed-release tablet and intravenous f …
Effect of intravenous infusion of omeprazole and ranitidine on twenty-four-hour intragastric pH in patients with a history of duodenal ulcer.
Kiilerich S, Rannem T, Elsborg L. Kiilerich S, et al. Digestion. 1995;56(1):25-30. doi: 10.1159/000201217. Digestion. 1995. PMID: 7895928 Clinical Trial.
The lower dose of omeprazole seemed to be somewhat less effective. Continuous infusion of ranitidine was as efficient as the higher omeprazole infusion although with a tendency to decreased pH levels towards the end of the 24-hour period. Thus, in orde …
The lower dose of omeprazole seemed to be somewhat less effective. Continuous infusion of ranitidine was as efficient as the h …
Intravenous esomeprazole.
Keating GM, Figgitt DP. Keating GM, et al. Drugs. 2004;64(8):875-82; discussion 883. doi: 10.2165/00003495-200464080-00008. Drugs. 2004. PMID: 15059043
In addition, a similar level of gastric acid control occurred with intravenous esomeprazole 40 mg administered by infusion or injection once daily for 10 days. ...In addition, control of basal and pentagastrin-stimulated gastric acid secretion was better with …
In addition, a similar level of gastric acid control occurred with intravenous esomeprazole 40 mg administered by infusion …
A STABILITY STUDY OF OMEPRAZOLE DILUTED IN SODIUM CHLORIDE FOR INTRAVENOUS INFUSION AND DISCUSSION REGARDING CURRENT PRACTICE IN UK PAEDIATRIC INTENSIVE CARE UNITS.
Morris S. Morris S. Arch Dis Child. 2016 Sep;101(9):e2. doi: 10.1136/archdischild-2016-311535.19. Arch Dis Child. 2016. PMID: 27540197
BACKGROUND: Omeprazole by intravenous infusion is occasionally warranted in children during episodes of acute upper gastro-intestinal bleeding. ...We also showed that a more concentrated solution of 0.8 mg/ml had the same degradation profile as 0.4 mg/ml.We r …
BACKGROUND: Omeprazole by intravenous infusion is occasionally warranted in children during episodes of acute upper gas …
Intravenous omeprazole in children: pharmacokinetics and effect on 24-hour intragastric pH.
Faure C, Michaud L, Shaghaghi EK, Popon M, Turck D, Navarro J, Jacqz-Aigrain E. Faure C, et al. J Pediatr Gastroenterol Nutr. 2001 Aug;33(2):144-8. doi: 10.1097/00005176-200108000-00009. J Pediatr Gastroenterol Nutr. 2001. PMID: 11568514 Clinical Trial.
OBJECTIVE: This study was designed to determine the pharmacokinetics and the optimal dosage of intravenous omeprazole in patients younger than 30 months of age. METHODS: Nine children (three girls), aged 4.5 to 27 months, with normal liver and renal functions requir …
OBJECTIVE: This study was designed to determine the pharmacokinetics and the optimal dosage of intravenous omeprazole in patie …
Seven-day intravenous low-dose omeprazole infusion reduces peptic ulcer rebleeding for patients with comorbidities.
Cheng HC, Chang WL, Yeh YC, Chen WY, Tsai YC, Sheu BS. Cheng HC, et al. Gastrointest Endosc. 2009 Sep;70(3):433-9. doi: 10.1016/j.gie.2009.01.041. Epub 2009 Jun 5. Gastrointest Endosc. 2009. PMID: 19500787 Clinical Trial.
However, the optimal duration is uncertain, especially for those patients with comorbidities. OBJECTIVE: To determine whether prolonged low-dose intravenous omeprazole could reduce rebleeding for patients with comorbidities. ...INTERVENTIONS: The enrolled patients w …
However, the optimal duration is uncertain, especially for those patients with comorbidities. OBJECTIVE: To determine whether prolonged low- …
Pharmacokinetics of omeprazole given by continuous intravenous infusion to patients with varying degrees of hepatic dysfunction.
Piqué JM, Feu F, de Prada G, Röhss K, Hasselgren G. Piqué JM, et al. Clin Pharmacokinet. 2002;41(12):999-1004. doi: 10.2165/00003088-200241120-00004. Clin Pharmacokinet. 2002. PMID: 12222996
OBJECTIVE: To examine the pharmacokinetics of omeprazole during intravenous infusion in patients with varying degrees of liver dysfunction (Child-Pugh categories A to C). ...CONCLUSION: Exposure to omeprazole following intravenous administration …
OBJECTIVE: To examine the pharmacokinetics of omeprazole during intravenous infusion in patients with varying degrees o …
Effect of repeated injection and continuous infusion of omeprazole and ranitidine on intragastric pH over 72 hours.
Netzer P, Gaia C, Sandoz M, Huluk T, Gut A, Halter F, Hüsler J, Inauen W. Netzer P, et al. Am J Gastroenterol. 1999 Feb;94(2):351-7. doi: 10.1111/j.1572-0241.1999.857_y.x. Am J Gastroenterol. 1999. PMID: 10022628 Clinical Trial.
However, data on the antisecretory effect beyond the first 24 h is scanty. In addition, the superiority of either infusion or injection of omeprazole remains unproven. Thus, we have compared the antisecretory effect of high dose omeprazole and ranitidine i …
However, data on the antisecretory effect beyond the first 24 h is scanty. In addition, the superiority of either infusion or injecti …
Effect of repeated boluses of intravenous omeprazole and primed infusions of ranitidine on 24-hour intragastric pH in healthy human subjects.
Teyssen S, Chari ST, Scheid J, Singer MV. Teyssen S, et al. Dig Dis Sci. 1995 Feb;40(2):247-55. doi: 10.1007/BF02065405. Dig Dis Sci. 1995. PMID: 7851185
In 19 healthy, fasting human subjects using continuous 24-hr gastric pH-metry, we studied two dosages of primed infusions of ranitidine (50 mg bolus followed by infusion of either 3 or 6 mg/kg body wt/24 hr) and six regimens of intravenous omeprazole ( …
In 19 healthy, fasting human subjects using continuous 24-hr gastric pH-metry, we studied two dosages of primed infusions of ranitidi …
Initial 48-hour acid inhibition by intravenous infusion of omeprazole, famotidine, or both in relation to cytochrome P450 2C19 genotype status.
Sugimoto M, Furuta T, Shirai N, Ikuma M, Hishida A, Ishizaki T. Sugimoto M, et al. Clin Pharmacol Ther. 2006 Nov;80(5):539-48. doi: 10.1016/j.clpt.2006.08.010. Clin Pharmacol Ther. 2006. PMID: 17112810 Clinical Trial.
METHODS: Fifteen Helicobacter pylori-positive volunteers with 3 different CYP2C19 genotypes were administered twice-daily intravenous infusions of 20 mg famotidine alone, 20 mg omeprazole alone, 10 mg omeprazole plus 10 mg famotidine (half-concomitant …
METHODS: Fifteen Helicobacter pylori-positive volunteers with 3 different CYP2C19 genotypes were administered twice-daily intravenous …
178 results