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Results: 1 to 20 of 149

1.

Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents.

Yang MH, Kim J, Khan IA, Walker LA, Khan SI.

Life Sci. 2014 Apr 1;100(2):75-84. doi: 10.1016/j.lfs.2014.01.075. Epub 2014 Feb 12. Review.

PMID:
24530873
[PubMed - indexed for MEDLINE]
2.

OSU-A9, an indole-3-carbinol derivative, induces cytotoxicity in acute myeloid leukemia through reactive oxygen species-mediated apoptosis.

Bai LY, Weng JR, Chiu CF, Wu CY, Yeh SP, Sargeant AM, Lin PH, Liao YM.

Biochem Pharmacol. 2013 Nov 15;86(10):1430-40. doi: 10.1016/j.bcp.2013.09.002. Epub 2013 Sep 13.

PMID:
24041743
[PubMed - indexed for MEDLINE]
3.

The Indole-3-carbinol cyclic tetrameric derivative CTet synergizes with cisplatin and doxorubicin in triple-negative breast cancer cell lines.

De Santi M, Galluzzi L, Duranti A, Magnani M, Brandi G.

Anticancer Res. 2013 May;33(5):1867-72.

PMID:
23645732
[PubMed - indexed for MEDLINE]
4.

Combination of fenretinide and indole-3-carbinol results in synergistic cytotoxic activity inducing apoptosis against human breast cancer cells in vitro.

Cevatemre B, Ari F, Sarimahmut M, Oral AY, Dere E, Kacar O, Adiguzel Z, Acilan C, Ulukaya E.

Anticancer Drugs. 2013 Jul;24(6):577-86. doi: 10.1097/CAD.0b013e328360a921.

PMID:
23542749
[PubMed - indexed for MEDLINE]
5.

I3C and ICZ inhibit migration by suppressing the EMT process and FAK expression in breast cancer cells.

Ho JN, Jun W, Choue R, Lee J.

Mol Med Rep. 2013 Feb;7(2):384-8. doi: 10.3892/mmr.2012.1198. Epub 2012 Nov 23.

PMID:
23179357
[PubMed - indexed for MEDLINE]
6.

Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies.

Brandi G, Fraternale A, Lucarini S, Paiardini M, De Santi M, Cervasi B, Paoletti MF, Galluzzi L, Duranti A, Magnani M.

Anticancer Agents Med Chem. 2013 May;13(4):654-62.

PMID:
23092288
[PubMed - indexed for MEDLINE]
7.

Modulation of CYP19 expression by cabbage juices and their active components: indole-3-carbinol and 3,3'-diindolylmethene in human breast epithelial cell lines.

Licznerska BE, Szaefer H, Murias M, Bartoszek A, Baer-Dubowska W.

Eur J Nutr. 2013 Aug;52(5):1483-92. doi: 10.1007/s00394-012-0455-9. Epub 2012 Oct 23. Erratum in: Eur J Nutr. 2014 Apr;53(3):995.

PMID:
23090135
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Induction of endoplasmic reticulum stress response by the indole-3-carbinol cyclic tetrameric derivative CTet in human breast cancer cell lines.

Galluzzi L, De Santi M, Crinelli R, De Marco C, Zaffaroni N, Duranti A, Brandi G, Magnani M.

PLoS One. 2012;7(8):e43249. doi: 10.1371/journal.pone.0043249. Epub 2012 Aug 14.

PMID:
22905241
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Indole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells.

Marconett CN, Singhal AK, Sundar SN, Firestone GL.

Mol Cell Endocrinol. 2012 Nov 5;363(1-2):74-84. doi: 10.1016/j.mce.2012.07.008. Epub 2012 Jul 24.

PMID:
22835548
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines.

Szaefer H, Licznerska B, Krajka-Kuźniak V, Bartoszek A, Baer-Dubowska W.

Nutr Cancer. 2012 Aug;64(6):879-88. doi: 10.1080/01635581.2012.690928. Epub 2012 Jun 20.

PMID:
22716309
[PubMed - indexed for MEDLINE]
11.

Synthesis and evaluation of the cytotoxicities of tetraindoles: observation that the 5-hydroxy tetraindole (SK228) induces G₂ arrest and apoptosis in human breast cancer cells.

Li WS, Wang CH, Ko S, Chang TT, Jen YC, Yao CF, More SV, Jao SC.

J Med Chem. 2012 Feb 23;55(4):1583-92. doi: 10.1021/jm2013425. Epub 2012 Feb 9.

PMID:
22277074
[PubMed - indexed for MEDLINE]
12.

Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.

Aronchik I, Chen T, Durkin KA, Horwitz MS, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.

Mol Carcinog. 2012 Nov;51(11):881-94. doi: 10.1002/mc.20857. Epub 2011 Oct 19.

PMID:
22012859
[PubMed - indexed for MEDLINE]
13.

(3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo.

Kim DJ, Reddy K, Kim MO, Li Y, Nadas J, Cho YY, Kim JE, Shim JH, Song NR, Carper A, Lubet RA, Bode AM, Dong Z.

Cancer Prev Res (Phila). 2011 Nov;4(11):1842-51. doi: 10.1158/1940-6207.CAPR-11-0158. Epub 2011 Sep 1.

PMID:
21885813
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inhibition of fatty acid synthase and Sp1 expression by 3,3'-diindolylmethane in human breast cancer cells.

Saati GE, Archer MC.

Nutr Cancer. 2011;63(5):790-4. doi: 10.1080/01635581.2011.570896. Epub 2011 Jun 22.

PMID:
21767081
[PubMed - indexed for MEDLINE]
15.

Adipocyte-derived factor as a modulator of oxidative estrogen metabolism: implications for obesity and estrogen-dependent breast cancer.

Bradlow HL, Sepkovic DW, Telang N, Tiwari R.

In Vivo. 2011 Jul-Aug;25(4):585-8.

PMID:
21709000
[PubMed - indexed for MEDLINE]
16.

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.

Marconett CN, Sundar SN, Tseng M, Tin AS, Tran KQ, Mahuron KM, Bjeldanes LF, Firestone GL.

Carcinogenesis. 2011 Sep;32(9):1315-23. doi: 10.1093/carcin/bgr116. Epub 2011 Jun 21.

PMID:
21693539
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines.

De Santi M, Galluzzi L, Lucarini S, Paoletti MF, Fraternale A, Duranti A, De Marco C, Fanelli M, Zaffaroni N, Brandi G, Magnani M.

Breast Cancer Res. 2011 Mar 24;13(2):R33. doi: 10.1186/bcr2855.

PMID:
21435243
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial.

Laidlaw M, Cockerline CA, Sepkovic DW.

Breast Cancer (Auckl). 2010 Dec 16;4:85-95. doi: 10.4137/BCBCR.S6505. Erratum in: Breast Cancer (Auckl). 2012;6:101.

PMID:
21234288
[PubMed]
Free PMC Article
19.

Diindolylmethane (DIM) spontaneously forms from indole-3-carbinol (I3C) during cell culture experiments.

Bradlow HL, Zeligs MA.

In Vivo. 2010 Jul-Aug;24(4):387-91.

PMID:
20668304
[PubMed - indexed for MEDLINE]
20.

Chemopreventive properties of indole-3-carbinol, diindolylmethane and other constituents of cardamom against carcinogenesis.

Acharya A, Das I, Singh S, Saha T.

Recent Pat Food Nutr Agric. 2010 Jun;2(2):166-77. Review.

PMID:
20653562
[PubMed - indexed for MEDLINE]

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