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The following terms were not found in PubMed: hydroxy-methoxy-N-, BLAHcarboxamide
Page 1
Etomidate.
[No authors listed] [No authors listed] 2023 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000359 Free Books & Documents. Review.
(18)F-labelled metomidate analogues as adrenocortical imaging agents.
Erlandsson M, Karimi F, Lindhe O, Långström B. Erlandsson M, et al. Nucl Med Biol. 2009 May;36(4):435-45. doi: 10.1016/j.nucmedbio.2009.01.014. Epub 2009 Mar 26. Nucl Med Biol. 2009. PMID: 19423012
INTRODUCTION: Two- and one-step syntheses of (18)F-labelled analogues of metomidate, such as 2-[(18)F]fluoroethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate (1), 2-[(18)F]fluoroethyl 1-[(1R)-1-(4-chlorophenyl)ethyl]-1H-imidazole-5-carboxylate (2), 2-[( …
INTRODUCTION: Two- and one-step syntheses of (18)F-labelled analogues of metomidate, such as 2-[(18)F]fluoroethyl 1-[(1R)-1- …
Structure-Based Screening to Discover New Inhibitors for Papain-like Proteinase of SARS-CoV-2: An In Silico Study.
Jamalan M, Barzegari E, Gholami-Borujeni F. Jamalan M, et al. J Proteome Res. 2021 Jan 1;20(1):1015-1026. doi: 10.1021/acs.jproteome.0c00836. Epub 2020 Dec 22. J Proteome Res. 2021. PMID: 33350309
Furthermore, 2-(4-fluorobenzyl)-5-nitro-1H-isoindole-1,3(2H)-dione (previously introduced as an inhibitor of cyclooxygenase-2), 3-nitro-N-[(1r)-1-phenylethyl]-5-(trifluoromethyl)benzamide (inhibitor against Mycobacterium tuberculosis), as well as the recently …
Furthermore, 2-(4-fluorobenzyl)-5-nitro-1H-isoindole-1,3(2H)-dione (previously introduced as an inhibitor of cyclooxygenase-2), 3-nitro-N-[( …
Substituted tetrahydrocarbazoles with potent activity against human papillomaviruses.
Gudmundsson KS, Sebahar PR, Richardson LD, Catalano JG, Boggs SD, Spaltenstein A, Sethna PB, Brown KW, Harvey R, Romines KR. Gudmundsson KS, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3489-92. doi: 10.1016/j.bmcl.2009.05.003. Epub 2009 May 7. Bioorg Med Chem Lett. 2009. PMID: 19457669
Several compounds with in vitro antiviral activity (W12 antiviral assay) in the low nanomolar range were identified and (1R)-6-bromo-N-[(1R)-1-phenylethyl]-2,3,4,9-tetrahydro-1H-carbazole-1-amine was selected for further evaluation....
Several compounds with in vitro antiviral activity (W12 antiviral assay) in the low nanomolar range were identified and (1R)-6-bromo-N-[( …
Epidermal growth factor receptor inhibitor PKI-166 governs cardiovascular protection without beneficial effects on the kidney in hypertensive 5/6 nephrectomized rats.
Ulu N, Mulder GM, Vavrinec P, Landheer SW, Duman-Dalkilic B, Gurdal H, Goris M, Duin M, van Dokkum RP, Buikema H, van Goor H, Henning RH. Ulu N, et al. J Pharmacol Exp Ther. 2013 Jun;345(3):393-403. doi: 10.1124/jpet.113.203497. Epub 2013 Mar 25. J Pharmacol Exp Ther. 2013. PMID: 23528611
The main objective of the present study was to investigate cardiac, vascular, and renal effects of EGFR inhibition by 4-[4-[[(1R)-1-phenylethyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenol (PKI-166) in the hypertensive chronic kidney disease model. ...
The main objective of the present study was to investigate cardiac, vascular, and renal effects of EGFR inhibition by 4-[4-[[(1R)- …
Studies towards the enantioselective synthesis of 5,6,8-trisubstituted amphibian indolizidine alkaloids via enaminone intermediates.
Michael JP, de Koning CB, van der Westhuyzen CW. Michael JP, et al. Org Biomol Chem. 2005 Mar 7;3(5):836-47. doi: 10.1039/b418062c. Epub 2005 Jan 31. Org Biomol Chem. 2005. PMID: 15731870
Investigations aimed at the enantioselective total synthesis of indolizidine 223A, a recently described 5,6,8-trisubstituted indolizidine alkaloid from a dendrobatid frog, are described. tert-Butyl (2R,3R)-3-amino-2-ethylhexanoate and its (2S,3R)-diastereomer, prepared in several …
Investigations aimed at the enantioselective total synthesis of indolizidine 223A, a recently described 5,6,8-trisubstituted indolizidine al …
Quantitation of low molecular mass substrates and products of enzyme catalyzed reactions using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Kang MJ, Tholey A, Heinzle E. Kang MJ, et al. Rapid Commun Mass Spectrom. 2000;14(21):1972-8. doi: 10.1002/1097-0231(20001115)14:21<1972::AID-RCM119>3.0.CO;2-5. Rapid Commun Mass Spectrom. 2000. PMID: 11085406
Two examples were investigated: the first one was a lipase catalyzed reaction which produces 2-methoxy-N-[(1R)-1-phenylethyl]acetamide (MET) using rac-alpha-phenylethylamine (PEA) as substrate. ...
Two examples were investigated: the first one was a lipase catalyzed reaction which produces 2-methoxy-N-[(1R)-1-phenylethy …
Nucleophile-dependent regio- and stereoselective ring opening of 1-azoniabicyclo[3.1.0]hexane tosylate.
Ji MK, Hertsen D, Yoon DH, Eum H, Goossens H, Waroquier M, Van Speybroeck V, D'hooghe M, De Kimpe N, Ha HJ. Ji MK, et al. Chem Asian J. 2014 Apr;9(4):1060-7. doi: 10.1002/asia.201301551. Epub 2014 Feb 2. Chem Asian J. 2014. PMID: 24488926
1-[(1R)-(1-Phenylethyl)]-1-azoniabicyclo[3.1.0]hexane tosylate was generated as a stable bicyclic aziridinium salt from the corresponding 2-(3-hydroxypropyl)aziridine upon reaction with p-toluenesulfonyl anhydride. ...
1-[(1R)-(1-Phenylethyl)]-1-azoniabicyclo[3.1.0]hexane tosylate was generated as a stable bicyclic aziridinium salt from …
12 results