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2010 1
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30 results

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Page 1
Showing results for histone zinc insulin
Your search for histon-zinc-insulin retrieved no results
Autophagy in the physiological endometrium and cancer.
Devis-Jauregui L, Eritja N, Davis ML, Matias-Guiu X, Llobet-Navàs D. Devis-Jauregui L, et al. Autophagy. 2021 May;17(5):1077-1095. doi: 10.1080/15548627.2020.1752548. Epub 2020 May 13. Autophagy. 2021. PMID: 32401642 Free PMC article. Review.
Current research efforts aiming to therapeutically exploit autophagy and the methodological approaches used are discussed.Abbreviations: 3-MA: 3-methyladenine; ACACA (acetyl-CoA carboxylase alpha); AICAR: 5-aminoimidazole-4-carboximide riboside; AKT: AKT serine/threonine kinase; …
Current research efforts aiming to therapeutically exploit autophagy and the methodological approaches used are discussed.Abbreviations: 3-M …
Gene methylation in gastric cancer.
Qu Y, Dang S, Hou P. Qu Y, et al. Clin Chim Acta. 2013 Sep 23;424:53-65. doi: 10.1016/j.cca.2013.05.002. Epub 2013 May 10. Clin Chim Acta. 2013. PMID: 23669186 Free article. Review.
Recent advancements in the rapidly evolving field of cancer epigenetics have shown extensive reprogramming of every component of the epigenetic machinery in cancer, including DNA methylation, histone modifications, nucleosome positioning, noncoding RNAs, and microRNAs. ...
Recent advancements in the rapidly evolving field of cancer epigenetics have shown extensive reprogramming of every component of the epigene …
Are epigenetic mechanisms and nutrition effective in male and female infertility?
Erdoğan K, Sanlier NT, Sanlier N. Erdoğan K, et al. J Nutr Sci. 2023 Sep 26;12:e103. doi: 10.1017/jns.2023.62. eCollection 2023. J Nutr Sci. 2023. PMID: 37771507 Free PMC article. Review.
It also interacts with vitamins B12, D and B6, biotin, choline, selenium, zinc, folic acid, resveratrol, quercetin and similar factors. To understand the molecular mechanisms regulating the expression of genes that affect infertility, the environment, the role of genotype, …
It also interacts with vitamins B12, D and B6, biotin, choline, selenium, zinc, folic acid, resveratrol, quercetin and similar factor …
Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis.
Liu Y, Jiang L, Sun C, Ireland N, Shah YM, Liu Y, Rui L. Liu Y, et al. Nat Commun. 2018 Jul 16;9(1):2751. doi: 10.1038/s41467-018-05309-y. Nat Commun. 2018. PMID: 30013137 Free PMC article.
Insulin stimulates lipogenesis but insulin resistance is also associated with increased hepatic lipogenesis in obesity. However, the underlying mechanism remains poorly characterized. Here, we show a noncanonical insulin-Snail1 pathway that suppresses lipogen …
Insulin stimulates lipogenesis but insulin resistance is also associated with increased hepatic lipogenesis in obesity. Howeve …
Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation.
Zhang T, Wang H, Saunee NA, Breslin MB, Lan MS. Zhang T, et al. Endocrinology. 2010 May;151(5):2030-9. doi: 10.1210/en.2009-1224. Epub 2010 Mar 9. Endocrinology. 2010. PMID: 20215568 Free PMC article.
INSM1 alone can selectively enhance acetylation of histone H4, whereas NeuroD1 and Pdx-1 favor the acetylation of histone H3. Both H3 and H4 histone acetylations facilitate insulin gene expression. The consistent functional effect of INSM1, either with …
INSM1 alone can selectively enhance acetylation of histone H4, whereas NeuroD1 and Pdx-1 favor the acetylation of histone H3. …
SAHA induces white fat browning and rectifies metabolic dysfunctions via activation of ZFPs.
Ma J, Wang Y, Ding J, Zhang S, Yang Y, Sun C. Ma J, et al. J Endocrinol. 2021 May 6;249(3):177-193. doi: 10.1530/JOE-20-0472. J Endocrinol. 2021. PMID: 33856361
Several histone deacetylase (HDAC) inhibitors have been shown to play beneficial roles in treating obesity and its related metabolic syndromes. ...Furthermore, SAHA accelerates blood glucose disposal, improves insulin sensitivity and attenuates fatty liver in obese …
Several histone deacetylase (HDAC) inhibitors have been shown to play beneficial roles in treating obesity and its related metabolic …
Overexpression of Slc30a7/ZnT7 increases the mitochondrial matrix levels of labile Zn(2+) and modifies histone modification in hyperinsulinemic cardiomyoblasts.
Tuncay E, Aktay I, Turan B. Tuncay E, et al. J Trace Elem Med Biol. 2023 Jul;78:127198. doi: 10.1016/j.jtemb.2023.127198. Epub 2023 May 12. J Trace Elem Med Biol. 2023. PMID: 37196548
Moreover, we determined significant increases in trimethylation of histone H3 lysine27, H3K27me3, and the mono-methylation of histone H3 lysine36, H3K36 in the ZnT7OE-cells, demonstrating the role of [Zn(2+)](Mit) in epigenetic regulation of cardiomyocytes under hyp …
Moreover, we determined significant increases in trimethylation of histone H3 lysine27, H3K27me3, and the mono-methylation of hist …
Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription.
Wang HW, Muguira M, Liu WD, Zhang T, Chen C, Aucoin R, Breslin MB, Lan MS. Wang HW, et al. J Endocrinol. 2008 Jul;198(1):29-39. doi: 10.1677/JOE-08-0001. Epub 2008 Apr 16. J Endocrinol. 2008. PMID: 18417529 Free PMC article.
The mechanism for transcriptional repression of the insulin gene by INSM1 is mediated through the recruitment of cyclin D1 and histone deacetylase-3 to the insulin promoter. Anti-INSM1 or anti-cyclin D1 morpholino treatment of fetal mouse pancreas enhances th …
The mechanism for transcriptional repression of the insulin gene by INSM1 is mediated through the recruitment of cyclin D1 and his …
beta-cells regeneration by WL15 of cysteine and glycine-rich protein 2 which reduces alloxan induced beta-cell dysfunction and oxidative stress through phosphoenolpyruvate carboxykinase and insulin pathway in zebrafish in-vivo larval model.
Guru A, Sudhakaran G, Almutairi MH, Almutairi BO, Juliet A, Arockiaraj J. Guru A, et al. Mol Biol Rep. 2022 Dec;49(12):11867-11879. doi: 10.1007/s11033-022-07882-4. Epub 2022 Oct 12. Mol Biol Rep. 2022. PMID: 36224446
To inhibit the beta-cells damages induced by the oxidative stress, the present study investigates the beneficial effect of various peptides (WL15, RF13, RW20, IW13 and MF18) of immune related proteins (cysteine and glycine-rich protein 2, histone acetyltransferase, vacuola …
To inhibit the beta-cells damages induced by the oxidative stress, the present study investigates the beneficial effect of various peptides …
30 results