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Year Number of Results
2002 2
2003 1
2004 3
2005 2
2008 1
2009 1
2010 1
2011 2
2013 2
2014 2
2015 1
2016 2
2020 1
2023 1
2024 0

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20 results

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Page 1
Cytokines induce HIF-1 DNA binding and the expression of HIF-1-dependent genes in cultured rat enterocytes.
Scharte M, Han X, Bertges DJ, Fink MP, Delude RL. Scharte M, et al. Am J Physiol Gastrointest Liver Physiol. 2003 Mar;284(3):G373-84. doi: 10.1152/ajpgi.00076.2002. Epub 2002 Oct 2. Am J Physiol Gastrointest Liver Physiol. 2003. PMID: 12388200 Free article.
Cellular adaptation to hypoxia depends, in part, on the transcription factor hypoxia-inducible factor-1 (HIF-1). Normoxic cells exposed to an inflammatory milieu often manifest phenotypic changes, such as increased glycolysis, that are re …
Cellular adaptation to hypoxia depends, in part, on the transcription factor hypoxia-inducible factor-1 (HIF …
Hypoxia induces glucose uptake and metabolism of adipose‑derived stem cells.
Park HS, Kim JH, Sun BK, Song SU, Suh W, Sung JH. Park HS, et al. Mol Med Rep. 2016 Nov;14(5):4706-4714. doi: 10.3892/mmr.2016.5796. Epub 2016 Oct 5. Mol Med Rep. 2016. PMID: 27748854
As determined by proteomic analysis and western blotting, GAPDH and enolase 1 (ENO1) expression were upregulated under hypoxia. In addition, lactate production was significantly increased, and mRNA levels of glycolytic enzymes, including GAPDH, ENO1, hexokinase 2 (H …
As determined by proteomic analysis and western blotting, GAPDH and enolase 1 (ENO1) expression were upregulated under hypoxia …
Aerobic glycolysis in colon cancer is repressed by naringin via the HIF1Α pathway.
Pan G, Zhang P, Chen A, Deng Y, Zhang Z, Lu H, Zhu A, Zhou C, Wu Y, Li S. Pan G, et al. J Zhejiang Univ Sci B. 2023 Mar 15;24(3):221-231. doi: 10.1631/jzus.B2200221. J Zhejiang Univ Sci B. 2023. PMID: 36915998 Free PMC article.
Moreover, naringin was used as an inhibitor of colon cancer cells to illustrate its effect on HIF1alpha function. The results showed that the HIF1alpha and enolase 2 (ENO2) levels in colon cancer tissues were highly correlated, and their high expression indicated a poor pr …
Moreover, naringin was used as an inhibitor of colon cancer cells to illustrate its effect on HIF1alpha function. The results showed that th …
Site-directed mutagenesis studies of the hypoxia-inducible factor-1alpha DNA-binding domain.
Michel G, Minet E, Mottet D, Remacle J, Michiels C. Michel G, et al. Biochim Biophys Acta. 2002 Oct 11;1578(1-3):73-83. doi: 10.1016/s0167-4781(02)00484-0. Biochim Biophys Acta. 2002. PMID: 12393189
Hypoxia-inducible factor-1 (HIF-1), a heterodimeric transcription factor, is activated when cells are exposed to hypoxia. ...These results bring new insights on the specificity of the protein/DNA interactions for HIF-1 towar …
Hypoxia-inducible factor-1 (HIF-1), a heterodimeric transcription factor, is activated when cells …
Seroreactivity against glycolytic enzymes in inflammatory bowel disease.
Vermeulen N, Vermeire S, Arijs I, Michiels G, Ballet V, Derua R, Waelkens E, Van Lommel L, Schuit F, Rutgeerts P, Bossuyt X. Vermeulen N, et al. Inflamm Bowel Dis. 2011 Feb;17(2):557-64. doi: 10.1002/ibd.21388. Inflamm Bowel Dis. 2011. PMID: 20629101
Seroreactivity to at least two antigens was detected in 16.7% of UC patients, 11.7% of CD patients, and none of the controls. Gene array experiments showed a significant upregulation of aldolase A, phosphoglycerate mutase, alpha-enolase, and pyruvate kinase m …
Seroreactivity to at least two antigens was detected in 16.7% of UC patients, 11.7% of CD patients, and none of the controls. Gene array exp …
Thyroid hormone responsive genes in cultured human fibroblasts.
Moeller LC, Dumitrescu AM, Walker RL, Meltzer PS, Refetoff S. Moeller LC, et al. J Clin Endocrinol Metab. 2005 Feb;90(2):936-43. doi: 10.1210/jc.2004-1768. Epub 2004 Oct 26. J Clin Endocrinol Metab. 2005. PMID: 15507505
The following genes not previously known to be induced by TH were identified and validated: aldo-keto reductase family 1 C1-3, collagen type VI alpha 3, member RAS oncogene family brain antigen RAB3B, platelet phosphofructokinase, hypoxia-inducible factor …
The following genes not previously known to be induced by TH were identified and validated: aldo-keto reductase family 1 C1-3, collagen type …
A Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma Cells.
Patil KS, Basak I, Pal R, Ho HP, Alves G, Chang EJ, Larsen JP, Møller SG. Patil KS, et al. PLoS One. 2015 Dec 3;10(12):e0143969. doi: 10.1371/journal.pone.0143969. eCollection 2015. PLoS One. 2015. PMID: 26633009 Free PMC article.
Several of the proteins are associated with neuronal processes, including peroxiredoxin-2 and -4, cofilin-1, prefoldin 2, alpha-enolase, human nucleoside diphosphate kinase B (Nm23) and 14-3-3 protein epsilon. Many of the differentially expressed proteins are involv …
Several of the proteins are associated with neuronal processes, including peroxiredoxin-2 and -4, cofilin-1, prefoldin 2, alpha-en …
Up-Regulation of ENO1 by HIF-1alpha in Retinal Pigment Epithelial Cells after Hypoxic Challenge Is Not Involved in the Regulation of VEGF Secretion.
Zheng F, Jang WC, Fung FK, Lo AC, Wong IY. Zheng F, et al. PLoS One. 2016 Feb 16;11(2):e0147961. doi: 10.1371/journal.pone.0147961. eCollection 2016. PLoS One. 2016. PMID: 26882120 Free PMC article.
PURPOSE: Alpha-enolase (ENO1), a major glycolytic enzyme, is reported to be over-expressed in various cancer tissues. It has been demonstrated to be regulated by the Hypoxia-inducible factor 1-alpha (HIF-1alpha), a crucial transcri …
PURPOSE: Alpha-enolase (ENO1), a major glycolytic enzyme, is reported to be over-expressed in various cancer tissues. It has b …
The effects and mechanisms of isoliquiritigenin loaded nanoliposomes regulated AMPK/mTOR mediated glycolysis in colorectal cancer.
Wang G, Yu Y, Wang YZ, Yin PH, Xu K, Zhang H. Wang G, et al. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):1231-1249. doi: 10.1080/21691401.2020.1825092. Artif Cells Nanomed Biotechnol. 2020. PMID: 32985258
Also, the key targets such as caveolin 1 (CAV1), glucose transporters and Akt/mTOR that promote glycolysis, and are activated via the induction of alpha-enolase (ENO1), fructose bisphosphate aldolase A (ALDOA) and monocarboxylate transporter 4 (MCT4) expressions wer …
Also, the key targets such as caveolin 1 (CAV1), glucose transporters and Akt/mTOR that promote glycolysis, and are activated via the induct …
Effect of proline analogues on activity of human prolyl hydroxylase and the regulation of HIF signal transduction pathway.
Ma X, Wang X, Cao J, Geng Z, Wang Z. Ma X, et al. PLoS One. 2014 Apr 22;9(4):e95692. doi: 10.1371/journal.pone.0095692. eCollection 2014. PLoS One. 2014. PMID: 24755992 Free PMC article.
Hypoxia inducible factor 1 (HIF-1) plays a pivotal role in cellular responses to hypoxia. ...Nine proteins, significantly regulated by PA1, were identified using 2-DE coupled with MALDI-TOF/TOF MS. Pyruvate kinase isozymes M1/M2 (PKM) and …
Hypoxia inducible factor 1 (HIF-1) plays a pivotal role in cellular responses to hypoxia. ...Nine …
20 results