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Showing results for heterosynkaryon
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Horizontal transmission of malignancy: in-vivo fusion of human lymphomas with hamster stroma produces tumors retaining human genes and lymphoid pathology.
Goldenberg DM, Gold DV, Loo M, Liu D, Chang CH, Jaffe ES. Goldenberg DM, et al. PLoS One. 2013;8(2):e55324. doi: 10.1371/journal.pone.0055324. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405135 Free PMC article.
We report the in-vivo fusion of two Hodgkin lymphomas with golden hamster cheek pouch cells, resulting in serially-transplanted (over 5-6 years) GW-532 and GW-584 heterosynkaryon tumor cells displaying both human and hamster DNA (by FISH), lymphoma-like morphology, aggress …
We report the in-vivo fusion of two Hodgkin lymphomas with golden hamster cheek pouch cells, resulting in serially-transplanted (over 5-6 ye …
Horizontal transmission and retention of malignancy, as well as functional human genes, after spontaneous fusion of human glioblastoma and hamster host cells in vivo.
Goldenberg DM, Zagzag D, Heselmeyer-Haddad KM, Berroa Garcia LY, Ried T, Loo M, Chang CH, Gold DV. Goldenberg DM, et al. Int J Cancer. 2012 Jul 1;131(1):49-58. doi: 10.1002/ijc.26327. Epub 2011 Aug 30. Int J Cancer. 2012. PMID: 21796629 Free PMC article.
Cell fusion in vitro has been used to study cancer, gene mapping and regulation, and the production of antibodies via hybridomas. However, in-vivo heterosynkaryon formation by cell-cell fusion has received less attention. ...
Cell fusion in vitro has been used to study cancer, gene mapping and regulation, and the production of antibodies via hybridomas. However, i …