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Cross-reactivity between myelin oligodendrocyte glycoprotein and human endogenous retrovirus W protein: nanotechnological evidence for the potential trigger of multiple sclerosis.
de Luca V, Martins Higa A, Malta Romano C, Pimenta Mambrini G, Peroni LA, Trivinho-Strixino F, Lima Leite F. de Luca V, et al. Micron. 2019 May;120:66-73. doi: 10.1016/j.micron.2019.02.005. Epub 2019 Feb 18. Micron. 2019. PMID: 30802755
The last consider the hypothesis of molecular mimicry mechanism, which is potentially triggered by viral antigen inducing MS autoimmunity. The Human Endogenous Retroviruses W family (HERV-W) is the subject of studies within this field, based on the detection …
The last consider the hypothesis of molecular mimicry mechanism, which is potentially triggered by viral antigen inducing MS autoimmunity. T …
High prevalence of antibodies against HERV-K10 in patients with testicular cancer but not with AIDS.
Goedert JJ, Sauter ME, Jacobson LP, Vessella RL, Hilgartner MW, Leitman SF, Fraser MC, Mueller-Lantzsch NG. Goedert JJ, et al. Cancer Epidemiol Biomarkers Prev. 1999 Apr;8(4 Pt 1):293-6. Cancer Epidemiol Biomarkers Prev. 1999. PMID: 10207631
Human endogenous retrovirus K10 (HERV-K10) env and gag expression has been detected in placenta, embryonic tissue, and cell lines. ...Antibody reactivity also occurs in approximately 5% of controls, perhaps because of nonspecific or cross-reactive epit …
Human endogenous retrovirus K10 (HERV-K10) env and gag expression has been detected in placenta, embryonic tissue, and cell li …
A comprehensive hybridization model allows whole HERV transcriptome profiling using high density microarray.
Becker J, Pérot P, Cheynet V, Oriol G, Mugnier N, Mommert M, Tabone O, Textoris J, Veyrieras JB, Mallet F. Becker J, et al. BMC Genomics. 2017 Apr 8;18(1):286. doi: 10.1186/s12864-017-3669-7. BMC Genomics. 2017. PMID: 28390408 Free PMC article.
BACKGROUND: Human endogenous retroviruses (HERVs) have received much attention for their implications in the etiology of many human diseases and their profound effect on evolution. ...METHODS: To refine our understanding of HERVs activity, we introduce here a new mi …
BACKGROUND: Human endogenous retroviruses (HERVs) have received much attention for their implications in the etiology of many …
Autoantibodies to human endogenous retrovirus-K are frequently detected in health and disease and react with multiple epitopes.
Herve CA, Lugli EB, Brand A, Griffiths DJ, Venables PJ. Herve CA, et al. Clin Exp Immunol. 2002 Apr;128(1):75-82. doi: 10.1046/j.1365-2249.2002.01735.x. Clin Exp Immunol. 2002. PMID: 11982593 Free PMC article.
A number of studies have found increased levels of antibodies to human endogenous retroviruses (HERVs) in autoimmune rheumatic diseases. It is not clear whether this immune response is driven by the HERV itself or by cross-reactions with an exog …
A number of studies have found increased levels of antibodies to human endogenous retroviruses (HERVs) in autoimmune rheumatic …
Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection.
Young GR, Ploquin MJ, Eksmond U, Wadwa M, Stoye JP, Kassiotis G. Young GR, et al. PLoS Pathog. 2012;8(5):e1002709. doi: 10.1371/journal.ppat.1002709. Epub 2012 May 10. PLoS Pathog. 2012. PMID: 22589728 Free PMC article.
Thus, although negative selection reduced the size and cross-reactivity of the available FV-reactive naive CD4+ T cell repertoire, it increased the overall avidity of the repertoire that responded to infection. These findings demonstrate that self proteins expressed …
Thus, although negative selection reduced the size and cross-reactivity of the available FV-reactive naive CD4+ T cell reperto …
High prevalence of an IgG response against murine leukemia virus (MLV) in patients with psoriasis.
Molès JP, Hadi JC, Guilhou JJ. Molès JP, et al. Virus Res. 2003 Aug;94(2):97-101. doi: 10.1016/s0168-1702(03)00137-0. Virus Res. 2003. PMID: 12902038
Increasing evidence suggests that human endogenous retroviruses (HERV) could participate in the pathogenesis of autoimmune diseases such as multiple sclerosis and lupus erythematosus. ...
Increasing evidence suggests that human endogenous retroviruses (HERV) could participate in the pathogenesis of autoimm …
Association between nuclear antigens and endogenous retrovirus in the generation of autoantibody responses in murine lupus.
Tucker RM, Roark CL, Santiago-Raber ML, Izui S, Kotzin BL. Tucker RM, et al. Arthritis Rheum. 2004 Nov;50(11):3626-36. doi: 10.1002/art.20623. Arthritis Rheum. 2004. PMID: 15529369 Free article.
RESULTS: Spontaneous autoantibody production in NZB/NZW mice reflects high-level autoimmune responses to nuclear antigens and gp70 that do not cross-react with the other antigen. However, both types of autoantibodies have the capability to bind to the endogenous
RESULTS: Spontaneous autoantibody production in NZB/NZW mice reflects high-level autoimmune responses to nuclear antigens and gp70 th …
The endogenous langur type D retrovirus PO-1-Lu and its exogenous counterparts in macaque and langur monkeys.
Sommerfelt MA, Harkestad N, Hunter E. Sommerfelt MA, et al. Virology. 2003 Oct 25;315(2):275-82. doi: 10.1016/s0042-6822(03)00548-8. Virology. 2003. PMID: 14585330 Free article.
PO-1-Lu, the endogenous type D retrovirus of langurs (Trachypithecus obscurus) has previously been considered a progenitor to the prototype type D retrovirus, Mason Pfizer monkey virus (M-PMV/SRV-3), that became established in macaque monkeys (Macaca spp.) following a zoon …
PO-1-Lu, the endogenous type D retrovirus of langurs (Trachypithecus obscurus) has previously been considered a progenitor to the pro …