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Neuroprotective effect of herniarin following transient focal cerebral ischemia in rats.
Asgharzade S, Khorrami MB, Forouzanfar F. Asgharzade S, et al. Metab Brain Dis. 2021 Dec;36(8):2505-2510. doi: 10.1007/s11011-021-00841-1. Epub 2021 Sep 14. Metab Brain Dis. 2021. PMID: 34519909
Herniarin at doses of 10 and 20 mg/kg was administered through intraperitoneal injection for 7 days before MCAO induction. ...Moreover, herniarin pretreatment decreased the levels of IL-1beta and TNF-alpha in the brain tissues of MCAO rats. ...
Herniarin at doses of 10 and 20 mg/kg was administered through intraperitoneal injection for 7 days before MCAO induction. ...Moreove …
The Alleviating Effect of Herniarin Against Ionizing Radiation-Induced Genotoxicity and Cytotoxicity in Human Peripheral Blood Lymphocytes.
Al Fares E, Sanikidze T, Kalmakhelidze S, Topuria D, Mansi L, Kitson S, Molazadeh M. Al Fares E, et al. Curr Radiopharm. 2022;15(2):141-147. doi: 10.2174/1874471014666211012104808. Curr Radiopharm. 2022. PMID: 34636317
BACKGROUND AND OBJECTIVE: Herniarin is a simple coumarin that is found naturally in some plant species. ...METHODS: Herniarin was added to human lymphocytes before irradiation with a dose of 2 Gy of Xrays. ...
BACKGROUND AND OBJECTIVE: Herniarin is a simple coumarin that is found naturally in some plant species. ...METHODS: Herniarin …
Herniarin-loaded solid lipid nanoparticles: promising molecular mechanism and therapeutic potential against pancreatic cancer line.
Delkhah AMD, Karimi E, Farivar S. Delkhah AMD, et al. Mol Biol Rep. 2023 Aug;50(8):6469-6479. doi: 10.1007/s11033-023-08560-9. Epub 2023 Jun 16. Mol Biol Rep. 2023. PMID: 37326747
BACKGROUND: The notion of cancer therapy is intrinsically subjected to multiple challenges due to the drug resistance and drug toxicity for normal tissues. Herniarin (7-methoxycoumarin) belongs to the naturally occurring aromatic phytochemicals and coumarins. ...According …
BACKGROUND: The notion of cancer therapy is intrinsically subjected to multiple challenges due to the drug resistance and drug toxicity for …
Herniarin, Dimethylfraxetin and Extracts from Tagetes lucida, in Psychosis Secondary to Ketamine and Its Interaction with Haloperidol.
Porras-Dávila SL, Jiménez-Ferrer E, Román Ramos R, González-Cortazar M, Almanza-Pérez JC, Herrera-Ruiz M. Porras-Dávila SL, et al. Plants (Basel). 2022 Oct 21;11(20):2789. doi: 10.3390/plants11202789. Plants (Basel). 2022. PMID: 36297813 Free PMC article.
The present work evaluated the effect of different extracts separated from this plant, TlHex, TlEA, TlMet, and TlAq, and of two isolated coumarins, herniarin (HN) and dimethylfraxetin (DF), on haloperidol-induced catalepsy (HAL), and psychotic behaviors provoked with a glu …
The present work evaluated the effect of different extracts separated from this plant, TlHex, TlEA, TlMet, and TlAq, and of two isolated cou …
The protective effect of herniarin on genotoxicity and apoptosis induced by cisplatin in bone marrow cells of rats.
Salehcheh M, Safari O, Khodayar MJ, Mojiri-Forushani H, Cheki M. Salehcheh M, et al. Drug Chem Toxicol. 2022 Jul;45(4):1470-1475. doi: 10.1080/01480545.2020.1842883. Epub 2020 Nov 3. Drug Chem Toxicol. 2022. PMID: 33143479
Herniarin is a member of simple coumarins, which are a group of common secondary metabolites in plants. ...Furthermore, herniarin significantly increased the levels of both red and white blood cells in peripheral blood. ...
Herniarin is a member of simple coumarins, which are a group of common secondary metabolites in plants. ...Furthermore, herniarin …
Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro.
Haghighitalab A, Matin MM, Bahrami AR, Iranshahi M, Haghighi F, Porsa H. Haghighitalab A, et al. Drug Chem Toxicol. 2014 Apr;37(2):156-62. doi: 10.3109/01480545.2013.834354. Epub 2013 Oct 14. Drug Chem Toxicol. 2014. PMID: 24116377
In this study, the enhancing effects of herniarin on cisplatin cytotoxicity were investigated. Cytotoxicity of herniarin on transitional cell carcinoma (TCC) cells was first investigated in comparison with umbelliferone, the parent compound for a large number of cou …
In this study, the enhancing effects of herniarin on cisplatin cytotoxicity were investigated. Cytotoxicity of herniarin on tr …
Effect of Herniarin on Cell Viability, Cell Cycle, and Erk Protein Levels in Different Stages of Bladder Cancer Cells.
Sanci TO, Terzi E, Oz Bedir BE, Gumustas M, Aydin T, Cakir A. Sanci TO, et al. Chem Biodivers. 2024 Mar;21(3):e202301645. doi: 10.1002/cbdv.202301645. Epub 2024 Feb 14. Chem Biodivers. 2024. PMID: 38235946
Herniarin's influence also extends to Erk signaling, a crucial pathway that regulates cell growth and differentiation. In conclusion, this study reveals herniarin's potential as a versatile agent in the treatment of bladder cancer....
Herniarin's influence also extends to Erk signaling, a crucial pathway that regulates cell growth and differentiation. In conclusion, …
The antioxidant, anti-angiogenic, and anticancer impact of chitosan-coated herniarin-graphene oxide nanoparticles (CHG-NPs).
Jasim LMM, Homayouni Tabrizi M, Darabi E, Jaseem MMM. Jasim LMM, et al. Heliyon. 2023 Sep 9;9(9):e20042. doi: 10.1016/j.heliyon.2023.e20042. eCollection 2023 Sep. Heliyon. 2023. PMID: 37809932 Free PMC article.
BACKGROUND: Herniarin, a simple coumarin found in chamomile leaf rosettes is known as the oxidative stress protector. ...METHOD: The Chitosan-coated Herniarin-Graphene oxide nanoparticles (CHG-NPs) were designed, produced, and characterized utilizing DLS, FESEM, FTI …
BACKGROUND: Herniarin, a simple coumarin found in chamomile leaf rosettes is known as the oxidative stress protector. ...METHOD: The …
Biosynthesis of coumarin and herniarin in lavender.
BROWN SA. BROWN SA. Science. 1962 Sep 21;137(3534):977-8. doi: 10.1126/science.137.3534.977. Science. 1962. PMID: 13873722
Coumarin and herniarin are formed in lavender from labeled o- and p-coumaric acids, respectively. At least part of the herniarin exists in lavender as a glycoside, presumably a 4-methoxycoumarinic acid glycoside, which yields free herniarin on hydrolysis. ...
Coumarin and herniarin are formed in lavender from labeled o- and p-coumaric acids, respectively. At least part of the herniarin …
Anti-Inflammatory and Neuroprotective Effects of Standardized Fractions in Herniarin and Daphnoretin from Distictis buccinatoria.
Liliana Porras-Dávila S, Zamilpa A, Jiménez-Ferrer E, Jiménez-Aparicio A, Alejandra Santillan-Urquiza M, Díaz-Patricio F, Herrera-Ruiz M. Liliana Porras-Dávila S, et al. Chem Biodivers. 2023 May;20(5):e202200969. doi: 10.1002/cbdv.202200969. Chem Biodivers. 2023. PMID: 36973180
The inhibition of local edema was: F1 (73.6 %), F2 (57 %), F3 (62.61 %), F4 (87.3 %), and F5 (93.57 %). Terpene fraction inhibited at 89.60 %, herniarin at 86.92 % (Emax 99.01 %, ED50 0.35 mg ear(-1) ), and daphnoretin at 86.41 %. ...D. buccinatoria has neuroprotective act …
The inhibition of local edema was: F1 (73.6 %), F2 (57 %), F3 (62.61 %), F4 (87.3 %), and F5 (93.57 %). Terpene fraction inhibited at 89.60 …
87 results