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Results: 1 to 20 of 1378

1.

A genome wide association study links glutamate receptor pathway to sporadic creutzfeldt-jakob disease risk.

Sanchez-Juan P, Bishop MT, Kovacs GG, Calero M, Aulchenko YS, Ladogana A, Boyd A, Lewis V, Ponto C, Calero O, Poleggi A, Carracedo Á, van der Lee SJ, Ströbel T, Rivadeneira F, Hofman A, Haïk S, Combarros O, Berciano J, Uitterlinden AG, Collins SJ, Budka H, Brandel JP, Laplanche JL, Pocchiari M, Zerr I, Knight RS, Will RG, van Duijn CM.

PLoS One. 2015 Apr 28;10(4):e0123654. doi: 10.1371/journal.pone.0123654. eCollection 2014.

2.

GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann RS, Herms S, Nalls M, Zhao W, Turner ST, Yaffe K, Lohman K, van Swieten JC, Kardia SL, Knopman DS, Meeks WM, Heiss G, Holliday EG, Schofield PW, Tanaka T, Stott DJ, Wang J, Ridker P, Gow AJ, Pattie A, Starr JM, Hocking LJ, Armstrong NJ, McLachlan S, Shulman JM, Pilling LC, Eiriksdottir G, Scott RJ, Kochan NA, Palotie A, Hsieh YC, Eriksson JG, Penman A, Gottesman RF, Oostra BA, Yu L, DeStefano AL, Beiser A, Garcia M, Rotter JI, Nöthen MM, Hofman A, Slagboom PE, Westendorp RG, Buckley BM, Wolf PA, Uitterlinden AG, Psaty BM, Grabe HJ, Bandinelli S, Chasman DI, Grodstein F, Räikkönen K, Lambert JC, Porteous DJ; Generation Scotland, Price JF, Sachdev PS, Ferrucci L, Attia JR, Rudan I, Hayward C, Wright AF, Wilson JF, Cichon S, Franke L, Schmidt H, Ding J, de Craen AJ, Fornage M, Bennett DA, Deary IJ, Ikram MA, Launer LJ, Fitzpatrick AL, Seshadri S, van Duijn CM, Mosley TH.

Mol Psychiatry. 2015 Apr 14. doi: 10.1038/mp.2015.37. [Epub ahead of print]

PMID:
25869804
3.
5.

Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function.

Hertz L, Chen Y, Waagepetersen HS.

J Neurochem. 2015 Apr 1. doi: 10.1111/jnc.13107. [Epub ahead of print]

PMID:
25832906
6.

Therapeutic Approaches to ModulatingGlutathione Levels as a Pharmacological strategy in Alzheimer's Disease.

Braidy N, Zarka M, Welch J, Bridge W.

Curr Alzheimer Res. 2015 Mar 24. [Epub ahead of print]

PMID:
25817250
7.

Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy.

Lin AP, Ramadan S, Stern RA, Box HC, Nowinski CJ, Ross BD, Mountford CE.

Alzheimers Res Ther. 2015 Mar 15;7(1):13. doi: 10.1186/s13195-015-0094-5. eCollection 2015.

8.

The kynurenine pathway and neurodegenerative disease.

Maddison DC, Giorgini F.

Semin Cell Dev Biol. 2015 Mar 12. pii: S1084-9521(15)00045-2. doi: 10.1016/j.semcdb.2015.03.002. [Epub ahead of print] Review.

PMID:
25773161
9.

α2-Adrenoceptors in the treatment of major neuropsychiatric disorders.

Langer SZ.

Trends Pharmacol Sci. 2015 Apr;36(4):196-202. doi: 10.1016/j.tips.2015.02.006. Epub 2015 Mar 13. Review.

PMID:
25771972
10.

Differential Effects of Palmitoylethanolamide against Amyloid-β Induced Toxicity in Cortical Neuronal and Astrocytic Primary Cultures from Wild-Type and 3xTg-AD Mice.

Tomasini MC, Borelli AC, Beggiato S, Ferraro L, Cassano T, Tanganelli S, Antonelli T.

J Alzheimers Dis. 2015 Mar 12. [Epub ahead of print]

PMID:
25765918
11.

Familial behavioral variant frontotemporal dementia associated with astrocyte-predominant tauopathy.

Ferrer I, Legati A, García-Monco JC, Gomez-Beldarrain M, Carmona M, Blanco R, Seeley WW, Coppola G.

J Neuropathol Exp Neurol. 2015 Apr;74(4):370-9. doi: 10.1097/NEN.0000000000000180.

PMID:
25756587
12.
13.

Therapeutic approaches to modulating glutathione levels as a pharmacological strategy in Alzheimer's disease.

Braidy N, Zarka M, Welch J, Bridge W.

Curr Alzheimer Res. 2015;12(4):298-313.

PMID:
25731620
14.

Uptake and metabolism of fructose by rat neocortical cells in vivo and by isolated nerve terminals in vitro.

Hassel B, Elsais A, Frøland AS, Taubøll E, Gjerstad L, Quan Y, Dingledine R, Rise F.

J Neurochem. 2015 May;133(4):572-81. doi: 10.1111/jnc.13079. Epub 2015 Mar 13.

PMID:
25708447
15.

PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning.

Johanssen T, Suphantarida N, Donnelly PS, Liu XM, Petrou S, Hill AF, Barnham KJ.

Neurobiol Dis. 2015 Feb 17. pii: S0969-9961(15)00028-5. doi: 10.1016/j.nbd.2015.02.008. [Epub ahead of print]

PMID:
25697105
16.

Glucagon-like peptide-1 protects the murine hippocampus against stressors via Akt and ERK1/2 signaling.

Yoshino Y, Ishisaka M, Tsujii S, Shimazawa M, Hara H.

Biochem Biophys Res Commun. 2015 Mar 6;458(2):274-9. doi: 10.1016/j.bbrc.2015.01.098. Epub 2015 Feb 7.

PMID:
25660451
17.

A blood-based, 7-metabolite signature for the early diagnosis of Alzheimer's disease.

Olazarán J, Gil-de-Gómez L, Rodríguez-Martín A, Valentí-Soler M, Frades-Payo B, Marín-Muñoz J, Antúnez C, Frank-García A, Acedo-Jiménez C, Morlán-Gracia L, Petidier-Torregrossa R, Guisasola MC, Bermejo-Pareja F, Sánchez-Ferro Á, Pérez-Martínez DA, Manzano-Palomo S, Farquhar R, Rábano A, Calero M.

J Alzheimers Dis. 2015 Jan 1;45(4):1157-73. doi: 10.3233/JAD-142925.

PMID:
25649659
18.

Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner.

DiBattista AM, Dumanis SB, Song JM, Bu G, Weeber E, William Rebeck G, Hoe HS.

Biochim Biophys Acta. 2015 May;1853(5):904-17. doi: 10.1016/j.bbamcr.2015.01.015. Epub 2015 Jan 31.

PMID:
25644714
19.

Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity.

Hull J, Patel V, El Hindy M, Lee C, Odeleye E, Hezwani M, Love S, Kehoe P, Chalmers K, Conway M.

J Alzheimers Dis. 2015 Jan 1;45(3):891-905. doi: 10.3233/JAD-142970.

PMID:
25633671
20.

Anorexigenic lipopeptides ameliorate central insulin signaling and attenuate tau phosphorylation in hippocampi of mice with monosodium glutamate-induced obesity.

Špolcová A, Mikulášková B, Holubová M, Nagelová V, Pirnik Z, Zemenová J, Haluzík M, Železná B, Galas MC, Maletínská L.

J Alzheimers Dis. 2015 Jan 1;45(3):823-35. doi: 10.3233/JAD-143150.

PMID:
25624414
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