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Results: 1 to 20 of 661

1.

Neuroprotective agents target molecular mechanisms of disease in ALS.

Zhu Y, Fotinos A, Mao LL, Atassi N, Zhou EW, Agondal S, Guan Y, Berry JD, Cudkowicz ME, Wang X.

Drug Discov Today. 2014 Sep 6. pii: S1359-6446(14)00343-2. doi: 10.1016/j.drudis.2014.08.016. [Epub ahead of print] Review.

PMID:
25205348
[PubMed - as supplied by publisher]
2.

VEGF levels in CSF and serum in mild ALS patients.

Gao L, Zhou S, Cai H, Gong Z, Zang D.

J Neurol Sci. 2014 Aug 29. pii: S0022-510X(14)00563-2. doi: 10.1016/j.jns.2014.08.031. [Epub ahead of print]

PMID:
25204587
[PubMed - as supplied by publisher]
3.

Loss of SIRT4 decreases GLT-1-dependent glutamate uptake and increases sensitivity to kainic acid.

Shih J, Mason A, Liu L, Higashimori H, Donmez G.

J Neurochem. 2014 Sep 6. doi: 10.1111/jnc.12942. [Epub ahead of print]

PMID:
25196144
[PubMed - as supplied by publisher]
4.

Novel NMDA receptor-specific desensitization/inactivation produced by ingestion of the neurotoxins, β-N-methylamino-l-alanine (BMAA) or β-N-oxalylamino-l-alanine (BOAA/β-ODAP).

Koenig JH, Goto JJ, Ikeda K.

Comp Biochem Physiol C Toxicol Pharmacol. 2014 Sep 3;167C:43-50. doi: 10.1016/j.cbpc.2014.08.006. [Epub ahead of print]

PMID:
25193276
[PubMed - as supplied by publisher]
5.

Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity.

Karki P, Smith K, Johnson J Jr, Aschner M, Lee E.

Neurochem Int. 2014 Aug 13. pii: S0197-0186(14)00185-5. doi: 10.1016/j.neuint.2014.08.002. [Epub ahead of print] Review.

PMID:
25128239
[PubMed - as supplied by publisher]
6.

Metabolic therapy with Deanna Protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model.

Ari C, Poff AM, Held HE, Landon CS, Goldhagen CR, Mavromates N, D'Agostino DP.

PLoS One. 2014 Jul 25;9(7):e103526. doi: 10.1371/journal.pone.0103526. eCollection 2014.

PMID:
25061944
[PubMed - in process]
Free PMC Article
7.

Therapeutic Targeting of Epigenetic Components in Amyotrophic Lateral Sclerosis (ALS).

Lee J, Ryu H, Yoon YJ, Kowall NW, Ryu H.

Curr Med Chem. 2014 Jul 6. [Epub ahead of print]

PMID:
25005187
[PubMed - as supplied by publisher]
8.

Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity.

Olmos G, Lladó J.

Mediators Inflamm. 2014;2014:861231. doi: 10.1155/2014/861231. Epub 2014 May 21. Review.

PMID:
24966471
[PubMed - in process]
Free PMC Article
9.

Activity of D-amino acid oxidase is widespread in the human central nervous system.

Sasabe J, Suzuki M, Imanishi N, Aiso S.

Front Synaptic Neurosci. 2014 Jun 10;6:14. doi: 10.3389/fnsyn.2014.00014. eCollection 2014.

PMID:
24959138
[PubMed]
Free PMC Article
10.

Stem cell factor-activated bone marrow ameliorates amyotrophic lateral sclerosis by promoting protective microglial migration.

Terashima T, Kojima H, Urabe H, Yamakawa I, Ogawa N, Kawai H, Chan L, Maegawa H.

J Neurosci Res. 2014 Jul;92(7):856-69.

PMID:
24936617
[PubMed - in process]
Free PMC Article
11.

Biomarkers And Future Targets For Development In Amyotrophic Lateral Sclerosis.

Menon P, Kiernan MC, Vucic S.

Curr Med Chem. 2014 Jun 1. [Epub ahead of print]

PMID:
24934359
[PubMed - as supplied by publisher]
12.

Potential Therapeutic Drugs and Methods for the Treatment of Amyotrophic Lateral Sclerosis.

Yacila G, Sari Y.

Curr Med Chem. 2014 Jun 1. [Epub ahead of print]

PMID:
24934355
[PubMed - as supplied by publisher]
13.

Advances in treating amyotrophic lateral sclerosis: insights from pathophysiological studies.

Vucic S, Rothstein JD, Kiernan MC.

Trends Neurosci. 2014 Aug;37(8):433-42. doi: 10.1016/j.tins.2014.05.006. Epub 2014 Jun 11. Review.

PMID:
24927875
[PubMed - in process]
14.

Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord.

Yin HZ, Yu S, Hsu CI, Liu J, Acab A, Wu R, Tao A, Chiang BJ, Weiss JH.

Exp Neurol. 2014 Jun 8;261C:1-9. doi: 10.1016/j.expneurol.2014.06.003. [Epub ahead of print]

PMID:
24918341
[PubMed - as supplied by publisher]
15.

Plasma amino acids patterns and age of onset of amyotrophic lateral sclerosis.

Cecchi M, Messina P, Airoldi L, Pupillo E, Bandettini di Poggio M, Calvo A, Filosto M, Lunetta C, Mandrioli J, Pisa F, Pastorelli R, Beghi E; Eurals Consortium.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep;15(5-6):371-5. doi: 10.3109/21678421.2014.920032. Epub 2014 Jun 6.

PMID:
24904978
[PubMed - in process]
16.

Differential regulation of glutamate transporter subtypes by pro-inflammatory cytokine TNF-α in cortical astrocytes from a rat model of amyotrophic lateral sclerosis.

Dumont AO, Goursaud S, Desmet N, Hermans E.

PLoS One. 2014 May 16;9(5):e97649. doi: 10.1371/journal.pone.0097649. eCollection 2014.

PMID:
24836816
[PubMed - in process]
Free PMC Article
17.

The role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS).

Paul P, de Belleroche J.

Front Synaptic Neurosci. 2014 Apr 16;6:10. doi: 10.3389/fnsyn.2014.00010. eCollection 2014. Review.

PMID:
24795623
[PubMed]
Free PMC Article
18.

[What are the applications of biomarkers in ALS today?].

Blasco H, Corcia P, Pradat PF.

Presse Med. 2014 May;43(5):569-79. doi: 10.1016/j.lpm.2013.12.014. Epub 2014 Apr 29. Review. French.

PMID:
24785140
[PubMed - indexed for MEDLINE]
19.

Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization.

Foran E, Rosenblum L, Bogush A, Pasinelli P, Trotti D.

Glia. 2014 Aug;62(8):1241-53. doi: 10.1002/glia.22677. Epub 2014 Apr 21.

PMID:
24753081
[PubMed - in process]
20.

The voltage-gated calcium channel blocker lomerizine is neuroprotective in motor neurons expressing mutant SOD1, but not TDP-43.

Tran LT, Gentil BJ, Sullivan KE, Durham HD.

J Neurochem. 2014 Aug;130(3):455-66. doi: 10.1111/jnc.12738. Epub 2014 May 9.

PMID:
24716897
[PubMed - indexed for MEDLINE]

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