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Items: 1 to 20 of 701

1.

Protective effect of valproic acid on cultured motor neurons under glutamate excitotoxic conditions. Ultrastructural study.

Nagańska E, Matyja E, Taraszewska A, Rafałowska J.

Folia Neuropathol. 2015;53(4):309-16.

PMID:
26785365
2.

Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors.

Siklos M, BenAissa M, Thatcher GR.

Acta Pharm Sin B. 2015 Nov;5(6):506-19. doi: 10.1016/j.apsb.2015.08.001. Epub 2015 Sep 26. Review.

3.

Multifactorial Gene Therapy Enhancing the Glutamate Uptake System and Reducing Oxidative Stress Delays Symptom Onset and Prolongs Survival in the SOD1-G93A ALS Mouse Model.

Benkler C, Barhum Y, Ben-Zur T, Offen D.

J Mol Neurosci. 2016 Jan;58(1):46-58. doi: 10.1007/s12031-015-0695-2. Epub 2015 Dec 21.

PMID:
26691332
4.

Disruption of TCA Cycle and Glutamate Metabolism Identified by Metabolomics in an In Vitro Model of Amyotrophic Lateral Sclerosis.

Veyrat-Durebex C, Corcia P, Piver E, Devos D, Dangoumau A, Gouel F, Vourc'h P, Emond P, Laumonnier F, Nadal-Desbarats L, Gordon PH, Andres CR, Blasco H.

Mol Neurobiol. 2015 Dec 14. [Epub ahead of print]

PMID:
26666663
5.

Aberrant association of misfolded SOD1 with Na<sup>+</sup>/K<sup>+</sup>ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS.

Ruegsegger C, Maharjan N, Goswami A, Filézac de L'Etang A, Weis J, Troost D, Heller M, Gut H, Saxena S.

Acta Neuropathol. 2015 Nov 30. [Epub ahead of print]

PMID:
26619836
6.

Cognitive impairment in amyotrophic lateral sclerosis, clues from the SOD1 mouse.

Spalloni A, Longone P.

Neurosci Biobehav Rev. 2016 Jan;60:12-25. doi: 10.1016/j.neubiorev.2015.11.006. Epub 2015 Nov 19. Review.

PMID:
26602023
7.

PET imaging studies show enhanced expression of mGluR5 and inflammatory response during progressive degeneration in ALS mouse model expressing SOD1-G93A gene.

Brownell AL, Kuruppu D, Kil KE, Jokivarsi K, Poutiainen P, Zhu A, Maxwell M.

J Neuroinflammation. 2015 Nov 24;12(1):217. doi: 10.1186/s12974-015-0439-9.

8.

Excitotoxicity in ALS: Overstimulation, or overreaction?

King AE, Woodhouse A, Kirkcaldie MT, Vickers JC.

Exp Neurol. 2016 Jan;275 Pt 1:162-71. doi: 10.1016/j.expneurol.2015.09.019. Epub 2015 Nov 13. Review.

PMID:
26584004
9.

Additive Neuroprotective Effects of the Multifunctional Iron Chelator M30 with Enriched Diet in a Mouse Model of Amyotrophic Lateral Sclerosis.

Golko-Perez S, Mandel S, Amit T, Kupershmidt L, Youdim MB, Weinreb O.

Neurotox Res. 2016 Feb;29(2):208-17. doi: 10.1007/s12640-015-9574-4. Epub 2015 Nov 18.

PMID:
26581376
10.

Bcl11b: A New Piece to the Complex Puzzle of Amyotrophic Lateral Sclerosis Neuropathogenesis?

Lennon MJ, Jones SP, Lovelace MD, Guillemin GJ, Brew BJ.

Neurotox Res. 2016 Feb;29(2):201-7. doi: 10.1007/s12640-015-9573-5. Epub 2015 Nov 12.

PMID:
26563995
11.

Homocysteine aggravates ROS-induced depression of transmitter release from motor nerve terminals: potential mechanism of peripheral impairment in motor neuron diseases associated with hyperhomocysteinemia.

Bukharaeva E, Shakirzyanova A, Khuzakhmetova V, Sitdikova G, Giniatullin R.

Front Cell Neurosci. 2015 Oct 6;9:391. doi: 10.3389/fncel.2015.00391. eCollection 2015.

12.

Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms.

Romano G, Appocher C, Scorzeto M, Klima R, Baralle FE, Megighian A, Feiguin F.

Hum Mol Genet. 2015 Nov 1;24(21):6134-45. doi: 10.1093/hmg/ddv330. Epub 2015 Aug 13.

13.

Investigation of vitamin D receptor polymorphisms in amyotrophic lateral sclerosis.

Török N, Török R, Klivényi P, Engelhardt J, Vécsei L.

Acta Neurol Scand. 2015 Jul 20. doi: 10.1111/ane.12463. [Epub ahead of print]

PMID:
26190642
14.

Neural and glial progenitor transplantation as a neuroprotective strategy for Amyotrophic Lateral Sclerosis (ALS).

Haidet-Phillips AM, Maragakis NJ.

Brain Res. 2015 Dec 2;1628(Pt B):343-50. doi: 10.1016/j.brainres.2015.06.035. Epub 2015 Jul 14. Review.

PMID:
26187754
15.

Astrocytes: New Targets for the Treatment of Neurodegenerative Diseases.

Finsterwald C, Magistretti PJ, Lengacher S.

Curr Pharm Des. 2015;21(25):3570-81.

PMID:
26166612
16.

Combined Treatment of an Amyotrophic Lateral Sclerosis Rat Model with Recombinant GOT1 and Oxaloacetic Acid: A Novel Neuroprotective Treatment.

Ruban A, Malina KC, Cooper I, Graubardt N, Babakin L, Jona G, Teichberg VI.

Neurodegener Dis. 2015;15(4):233-42. doi: 10.1159/000382034. Epub 2015 Jun 23.

PMID:
26113413
17.

Postactivation depression of the Ia EPSP in motoneurons is reduced in both the G127X SOD1 model of amyotrophic lateral sclerosis and in aged mice.

Hedegaard A, Lehnhoff J, Moldovan M, Grøndahl L, Petersen NC, Meehan CF.

J Neurophysiol. 2015 Aug;114(2):1196-210. doi: 10.1152/jn.00745.2014. Epub 2015 Jun 17.

PMID:
26084911
18.

Miro1 deficiency in amyotrophic lateral sclerosis.

Zhang F, Wang W, Siedlak SL, Liu Y, Liu J, Jiang K, Perry G, Zhu X, Wang X.

Front Aging Neurosci. 2015 May 26;7:100. doi: 10.3389/fnagi.2015.00100. eCollection 2015.

19.

N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis.

Sirianni AC, Jiang J, Zeng J, Mao LL, Zhou S, Sugarbaker P, Zhang X, Li W, Friedlander RM, Wang X.

J Neurochem. 2015 Sep;134(5):956-68. doi: 10.1111/jnc.13190. Epub 2015 Jul 14.

PMID:
26031348
20.

Review of Dextromethorphan 20 mg/Quinidine 10 mg (NUEDEXTA(®)) for Pseudobulbar Affect.

Pioro EP.

Neurol Ther. 2014 Jun 17;3(1):15-28. doi: 10.1007/s40120-014-0018-5. eCollection 2014 Jun. Review.

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