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Results: 1 to 20 of 127

1.

LKB1 preserves genome integrity by stimulating BRCA1 expression.

Gupta R, Liu AY, Glazer PM, Wajapeyee N.

Nucleic Acids Res. 2015 Jan;43(1):259-71. doi: 10.1093/nar/gku1294. Epub 2014 Dec 8.

2.

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.

Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM, Slack FJ.

Nature. 2015 Feb 5;518(7537):107-10. doi: 10.1038/nature13905. Epub 2014 Nov 17.

PMID:
25409146
3.

Therapeutic genome mutagenesis using synthetic donor DNA and triplex-forming molecules.

Reza F, Glazer PM.

Methods Mol Biol. 2015;1239:39-73. doi: 10.1007/978-1-4939-1862-1_4.

PMID:
25408401
4.

Single-Stranded ╬│PNAs for In Vivo Site-Specific Genome Editing via Watson-Crick Recognition.

Bahal R, Quijano E, McNeer NA, Liu Y, Bhunia DC, Lopez-Giraldez F, Fields RJ, Saltzman WM, Ly DH, Glazer PM.

Curr Gene Ther. 2014;14(5):331-42.

5.

Modified Poly(lactic-co-glycolic Acid) Nanoparticles for Enhanced Cellular Uptake and Gene Editing in the Lung.

Fields RJ, Quijano E, McNeer NA, Caputo C, Bahal R, Anandalingam K, Egan ME, Glazer PM, Saltzman WM.

Adv Healthc Mater. 2015 Feb 18;4(3):361-6. doi: 10.1002/adhm.201400355. Epub 2014 Aug 25.

PMID:
25156908
6.

Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.

Lu Y, Wajapeyee N, Turker MS, Glazer PM.

Cell Rep. 2014 Jul 24;8(2):501-13. doi: 10.1016/j.celrep.2014.06.035. Epub 2014 Jul 17.

7.

Targeted genome modification via triple helix formation.

Ricciardi AS, McNeer NA, Anandalingam KK, Saltzman WM, Glazer PM.

Methods Mol Biol. 2014;1176:89-106. doi: 10.1007/978-1-4939-0992-6_8.

PMID:
25030921
8.

HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutS╬▒.

Zhang M, Xiang S, Joo HY, Wang L, Williams KA, Liu W, Hu C, Tong D, Haakenson J, Wang C, Zhang S, Pavlovicz RE, Jones A, Schmidt KH, Tang J, Dong H, Shan B, Fang B, Radhakrishnan R, Glazer PM, Matthias P, Koomen J, Seto E, Bepler G, Nicosia SV, Chen J, Li C, Gu L, Li GM, Bai W, Wang H, Zhang X.

Mol Cell. 2014 Jul 3;55(1):31-46. doi: 10.1016/j.molcel.2014.04.028. Epub 2014 May 29.

PMID:
24882211
9.

The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.

Colis LC, Woo CM, Hegan DC, Li Z, Glazer PM, Herzon SB.

Nat Chem. 2014 Jun;6(6):504-10. doi: 10.1038/nchem.1944. Epub 2014 May 11.

10.

Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.

Scanlon SE, Glazer PM.

Mol Cancer Res. 2014 Jul;12(7):1016-28. doi: 10.1158/1541-7786.MCR-13-0628. Epub 2014 Mar 31.

PMID:
24688021
11.

Triplex-mediated genome targeting and editing.

Reza F, Glazer PM.

Methods Mol Biol. 2014;1114:115-42. doi: 10.1007/978-1-62703-761-7_8.

PMID:
24557900
12.

Introduction.

Sweasy JB, Glazer PM.

Yale J Biol Med. 2013 Dec;86(4):441-2. No abstract available.

13.

Hypoxia and DNA repair.

Glazer PM, Hegan DC, Lu Y, Czochor J, Scanlon SE.

Yale J Biol Med. 2013 Dec 13;86(4):443-51.

14.

Peptide nucleic acid-mediated recombination for targeted genomic repair and modification.

Schleifman EB, Glazer PM.

Methods Mol Biol. 2014;1050:207-22. doi: 10.1007/978-1-62703-553-8_17.

PMID:
24297362
15.

Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice.

Schleifman EB, McNeer NA, Jackson A, Yamtich J, Brehm MA, Shultz LD, Greiner DL, Kumar P, Saltzman WM, Glazer PM.

Mol Ther Nucleic Acids. 2013 Nov 19;2:e135. doi: 10.1038/mtna.2013.59.

16.

microRNAs in cancer cell response to ionizing radiation.

Czochor JR, Glazer PM.

Antioxid Redox Signal. 2014 Jul 10;21(2):293-312. doi: 10.1089/ars.2013.5718. Epub 2014 Feb 4.

PMID:
24206455
17.

Radiation sensitivity and sensitization in melanoma.

Shahbazian D, Bindra RS, Kluger HM, Glazer PM.

Pigment Cell Melanoma Res. 2013 Nov;26(6):928-30. doi: 10.1111/pcmr.12147. Epub 2013 Aug 12. No abstract available.

18.

Triplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells.

Chin JY, Reza F, Glazer PM.

Mol Ther. 2013 Mar;21(3):580-7. doi: 10.1038/mt.2012.262. Epub 2013 Jan 22.

19.

Targeting cancer with a lupus autoantibody.

Hansen JE, Chan G, Liu Y, Hegan DC, Dalal S, Dray E, Kwon Y, Xu Y, Xu X, Peterson-Roth E, Geiger E, Liu Y, Gera J, Sweasy JB, Sung P, Rockwell S, Nishimura RN, Weisbart RH, Glazer PM.

Sci Transl Med. 2012 Oct 24;4(157):157ra142. doi: 10.1126/scitranslmed.3004385.

20.

Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo.

McNeer NA, Schleifman EB, Cuthbert A, Brehm M, Jackson A, Cheng C, Anandalingam K, Kumar P, Shultz LD, Greiner DL, Mark Saltzman W, Glazer PM.

Gene Ther. 2013 Jun;20(6):658-69. doi: 10.1038/gt.2012.82. Epub 2012 Oct 18.

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