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Page 1
Did you mean fluoromethylations (3 results)?
Enzymatic Fluoromethylation Enabled by the S-Adenosylmethionine Analog Te-Adenosyl-L-(fluoromethyl)homotellurocysteine.
Neti SS, Wang B, Iwig DF, Onderko EL, Booker SJ. Neti SS, et al. ACS Cent Sci. 2023 May 8;9(5):905-914. doi: 10.1021/acscentsci.2c01385. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252363 Free PMC article.
Fluoromethyl, difluoromethyl, and trifluoromethyl groups are present in numerous pharmaceuticals and agrochemicals, where they play critical roles in the efficacy and metabolic stability of these molecules. ...Herein, we describe the synthesis and use of Te-adenosyl-L-( …
Fluoromethyl, difluoromethyl, and trifluoromethyl groups are present in numerous pharmaceuticals and agrochemicals, where they play c …
Reagents for Selective Fluoromethylation: A Challenge in Organofluorine Chemistry.
Reichel M, Karaghiosoff K. Reichel M, et al. Angew Chem Int Ed Engl. 2020 Jul 20;59(30):12268-12281. doi: 10.1002/anie.201913175. Epub 2020 Jun 4. Angew Chem Int Ed Engl. 2020. PMID: 32022357 Free PMC article. Review.
This has recently prompted many researchers to develop alternative fluoromethylation agents. This Minireview summarizes both the classical and new generation of fluoromethylating agents. ...
This has recently prompted many researchers to develop alternative fluoromethylation agents. This Minireview summarizes both the clas …
Sevoflurane.
[No authors listed] [No authors listed] 2020 Nov 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2020 Nov 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000564 Free Books & Documents. Review.
Fluorinated S-Adenosylmethionine as a Reagent for Enzyme-Catalyzed Fluoromethylation.
Peng J, Liao C, Bauer C, Seebeck FP. Peng J, et al. Angew Chem Int Ed Engl. 2021 Dec 20;60(52):27178-27183. doi: 10.1002/anie.202108802. Epub 2021 Nov 10. Angew Chem Int Ed Engl. 2021. PMID: 34597444
We demonstrate the ability of halide methyltransferases to form fluorinated SAM (S-adenosyl-S-(fluoromethyl)-L-homocysteine) from S-adenosylhomocysteine and fluoromethyliodide. Fluorinated SAM (F-SAM) is too unstable for isolation, but is accepted as a substrate by C-, N- …
We demonstrate the ability of halide methyltransferases to form fluorinated SAM (S-adenosyl-S-(fluoromethyl)-L-homocysteine) from S-a …
Enzymatic Fluoromethylation as a Tool for ATP-Independent Ligation.
Peng J, Hughes GR, Müller MM, Seebeck FP. Peng J, et al. Angew Chem Weinheim Bergstr Ger. 2024 Jan 2;136(1):e202312104. doi: 10.1002/ange.202312104. Epub 2023 Nov 29. Angew Chem Weinheim Bergstr Ger. 2024. PMID: 38516647 Free PMC article.
Fluticasone, Inhaled.
[No authors listed] [No authors listed] 2021 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999836 Free Books & Documents. Review.
Fluticasone, Topical.
[No authors listed] [No authors listed] 2024 Jan 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2024 Jan 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999824 Free Books & Documents. Review.
Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides.
Du Y, Chen S, Huang A, Chen Y, Liu YL, Song G, Tang RY, Xu H, Yao G, Li Z. Du Y, et al. Org Lett. 2022 Feb 18;24(6):1341-1345. doi: 10.1021/acs.orglett.1c04367. Epub 2022 Feb 7. Org Lett. 2022. PMID: 35129989
Herein we report the first versatile and expeditious method for the site-selective C-H fluoromethylation of aryl iodides via Pd/norbornene cooperative catalysis, which could work as a robust toolbox for the diversity-oriented synthesis (DOS) of fluoromethylated aren …
Herein we report the first versatile and expeditious method for the site-selective C-H fluoromethylation of aryl iodides via Pd/norbo …
3,450 results