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Year Number of Results
1991 1
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2000 2
2001 2
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2004 1
2005 1
2006 2
2007 2
2008 2
2009 2
2010 4
2011 6
2012 5
2013 4
2014 4
2016 3
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2019 5
2020 1
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2022 1
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54 results

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Page 1
Landscape of genomic alterations in cervical carcinomas.
Ojesina AI, Lichtenstein L, Freeman SS, Pedamallu CS, Imaz-Rosshandler I, Pugh TJ, Cherniack AD, Ambrogio L, Cibulskis K, Bertelsen B, Romero-Cordoba S, Treviño V, Vazquez-Santillan K, Guadarrama AS, Wright AA, Rosenberg MW, Duke F, Kaplan B, Wang R, Nickerson E, Walline HM, Lawrence MS, Stewart C, Carter SL, McKenna A, Rodriguez-Sanchez IP, Espinosa-Castilla M, Woie K, Bjorge L, Wik E, Halle MK, Hoivik EA, Krakstad C, Gabiño NB, Gómez-Macías GS, Valdez-Chapa LD, Garza-Rodríguez ML, Maytorena G, Vazquez J, Rodea C, Cravioto A, Cortes ML, Greulich H, Crum CP, Neuberg DS, Hidalgo-Miranda A, Escareno CR, Akslen LA, Carey TE, Vintermyr OK, Gabriel SB, Barrera-Saldaña HA, Melendez-Zajgla J, Getz G, Salvesen HB, Meyerson M. Ojesina AI, et al. Nature. 2014 Feb 20;506(7488):371-5. doi: 10.1038/nature12881. Epub 2013 Dec 25. Nature. 2014. PMID: 24390348 Free PMC article.
Previously unknown somatic mutations in 79 primary squamous cell carcinomas include recurrent E322K substitutions in the MAPK1 gene (8%), inactivating mutations in the HLA-B gene (9%), and mutations in EP300 (16%), FBXW7 (15%), NFE2L2 (4%), TP53 (5%) a …
Previously unknown somatic mutations in 79 primary squamous cell carcinomas include recurrent E322K substitutions in the MAPK1 …
Identification of Targetable ERBB2 Aberrations in Head and Neck Squamous Cell Carcinoma.
Birkeland AC, Yanik M, Tillman BN, Scott MV, Foltin SK, Mann JE, Michmerhuizen NL, Ludwig ML, Sandelski MM, Komarck CM, Carey TE, Prince ME, Bradford CR, McHugh JB, Spector ME, Brenner JC. Birkeland AC, et al. JAMA Otolaryngol Head Neck Surg. 2016 Jun 1;142(6):559-67. doi: 10.1001/jamaoto.2016.0335. JAMA Otolaryngol Head Neck Surg. 2016. PMID: 27077364 Free PMC article.
ERBB2 status in head and neck squamous cell carcinoma (HNSCC) has not been well studied. ...Western blotting for HNSCC cell line ERBB2 expression and cell survival assays after treatment with ERBB2 inhibitors w
ERBB2 status in head and neck squamous cell carcinoma (HNSCC) has not been well studied. ...Wester
Specific Targeting of HER2-Positive Head and Neck Squamous Cell Carcinoma Line HN5 by Idarubicin-ZHER2 Affibody Conjugate.
Ghanemi M, Pourshohod A, Ghaffari MA, Kheirollah A, Amin M, Zeinali M, Jamalan M. Ghanemi M, et al. Curr Cancer Drug Targets. 2019;19(1):65-73. doi: 10.2174/1568009617666170427105417. Curr Cancer Drug Targets. 2019. PMID: 28460618
BACKGROUND: Expression of human epidermal growth factor receptor type 2 (HER2) in head and neck squamous cell carcinoma (HNSCC) cell line HN5 can be employed with great opportunities of success for specific targeting of anti-cancer …
BACKGROUND: Expression of human epidermal growth factor receptor type 2 (HER2) in head and neck squamous cell
Expression of c-erbB receptors, MMPs and VEGF in head and neck squamous cell carcinoma.
Lim SC. Lim SC. Biomed Pharmacother. 2005 Oct;59 Suppl 2:S366-9. doi: 10.1016/s0753-3322(05)80080-0. Biomed Pharmacother. 2005. PMID: 16507411 Review.
Head and neck squamous cell carcinomas (HNSCC) are characterized by a marked propensity for local invasion and cervical lymph node metastasis. The aim of this article was to review the expression of epidermal growth factor receptor (EGFR), c-
Head and neck squamous cell carcinomas (HNSCC) are characterized by a marked propensity for local invasion and c
Expression of immunohistochemical markers in non-oropharyngeal head and neck squamous cell carcinoma in Ghana.
Owusu-Afriyie O, Owiredu WKBA, Owusu-Danquah K, Komarck C, Foltin SK, Larsen-Reindorf R, Acheampong E, Quayson SE, Prince MEP, McHugh JB, Donkor P, Merajver SD, Brenner JC. Owusu-Afriyie O, et al. PLoS One. 2018 Aug 23;13(8):e0202790. doi: 10.1371/journal.pone.0202790. eCollection 2018. PLoS One. 2018. PMID: 30138436 Free PMC article.
BACKGROUND: Head and neck cancers include carcinomas of the oral cavity, larynx, sinonasal tract and nasopharynx. ...The purpose of this study was to determine the expression of p53, p16, EGFR, Cyclin-D1 and HER2 among patients with non-oropharyngeal head and …
BACKGROUND: Head and neck cancers include carcinomas of the oral cavity, larynx, sinonasal tract and nasopharynx. ...The purpo …
Gene amplification and protein overexpression of EGFR and ERBB2 in sinonasal squamous cell carcinoma.
López F, Llorente JL, Oviedo CM, Vivanco B, Marcos CÁ, García-Inclán C, Scola B, Hermsen MA. López F, et al. Cancer. 2012 Apr 1;118(7):1818-26. doi: 10.1002/cncr.26451. Epub 2011 Aug 25. Cancer. 2012. PMID: 22009799 Free article.
BACKGROUND: Sinonasal squamous cell carcinomas (SNSCCs) are rare tumors with no etiologic link to tobacco or alcohol, as opposed to other squamous cell carcinomas of the head and neck. ...Therefore, there is a need for new therapeutic pos …
BACKGROUND: Sinonasal squamous cell carcinomas (SNSCCs) are rare tumors with no etiologic link to tobacco or alcohol, as oppos …
FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells.
Zhao F, Ge F, Xie M, Li Z, Zang C, Kong L, Pu Y, Zheng X, Tan Y. Zhao F, et al. Clin Exp Metastasis. 2022 Aug;39(4):623-639. doi: 10.1007/s10585-022-10169-4. Epub 2022 May 7. Clin Exp Metastasis. 2022. PMID: 35524932 Free PMC article.
N(6)-methyladenosine (m(6)A) is the most prevalent and internal modification that occurs in the messenger RNAs of eukaryotes. However, knowledge of the impact of these modifications on gene expression regulation remains limited. By using the in vitro MeRIP-seq and RNA-seq …
N(6)-methyladenosine (m(6)A) is the most prevalent and internal modification that occurs in the messenger RNAs of eukaryotes. However, knowl …
Human epidermal growth factor receptor 2 expression in head and neck squamous cell carcinoma: Variation within and across primary tumor sites, and implications for antigen-specific immunotherapy.
Warren EAK, Anil J, Castro PD, Kemnade J, Suzuki M, Hegde M, Hicks J, Yu W, Sandulache V, Sikora AG. Warren EAK, et al. Head Neck. 2021 Jul;43(7):1983-1994. doi: 10.1002/hed.26662. Epub 2021 Mar 4. Head Neck. 2021. PMID: 33660372 Free PMC article.
BACKGROUND: The purpose of this study is to describe human epidermal growth factor 2 (HER2) overexpression in head and neck squamous cell carcinoma (HNSCC) and re-evaluate its potential as a target for HER2-directed immunotherapies. ...
BACKGROUND: The purpose of this study is to describe human epidermal growth factor 2 (HER2) overexpression in head and neck
Prognostic impact of HER-2/neu expression on squamous head and neck carcinomas.
Cavalot A, Martone T, Roggero N, Brondino G, Pagano M, Cortesina G. Cavalot A, et al. Head Neck. 2007 Jul;29(7):655-64. doi: 10.1002/hed.20574. Head Neck. 2007. PMID: 17315173
BACKGROUND: HER-2/neu gene amplification and protein overexpression have been identified in various solid tumors, but its prognostic relevance in head and neck squamous cell carcinoma (HNSCC) is still controversial. ...CONCLUSIONS: HER2/n …
BACKGROUND: HER-2/neu gene amplification and protein overexpression have been identified in various solid tumors, but its prognostic …
Rationale for Using Irreversible Epidermal Growth Factor Receptor Inhibitors in Combination with Phosphatidylinositol 3-Kinase Inhibitors for Advanced Head and Neck Squamous Cell Carcinoma.
Michmerhuizen NL, Leonard E, Matovina C, Harris M, Herbst G, Kulkarni A, Zhai J, Jiang H, Carey TE, Brenner JC. Michmerhuizen NL, et al. Mol Pharmacol. 2019 May;95(5):528-536. doi: 10.1124/mol.118.115162. Epub 2019 Mar 11. Mol Pharmacol. 2019. PMID: 30858165 Free PMC article.
Head and neck squamous cell carcinoma (HNSCC) is a common and debilitating form of cancer characterized by poor patient outcomes and low survival rates. In HNSCC, genetic aberrations in phosphatidylinositol 3-kinase (PI3K) and epidermal growth f
Head and neck squamous cell carcinoma (HNSCC) is a common and debilitating form of cancer characterized b
54 results