Figure 4

Ictal SPECT in extra temporal epilepsy showing (a) right frontal hyperperfusion in a patient with frontal lobe epilepsy (b) right occipital hyperperfusion in a patient with occipital lobe epilepsy.

Role of Single Photon Emission Computed Tomography in Epilepsy

Int J Mol Imaging. 2011;2011:803920.
Figure 2

Illustration of the value of ictal SPECT in a 38-year-old male with intractable epilepsy. The MRI was normal. The Tc-99m HMPAO ictal brain SPECT scan showed a focal area of hyperperfusion in the right frontal area. In this case, the interictal scan shows normal perfusion to this area of the brain.

SPECT Imaging of Epilepsy: An Overview and Comparison with F-18 FDG PET

Int J Mol Imaging. 2011;2011:813028.
Fig. 1

Convergent multimodal imaging in a 11-year-old boy with left temporal lobe epilepsy. Cortex thickening in the left temporal lobe is seen on the corresponding coronal T1W1 MRI. SISCOM demonstrated a cluster of hyperperfusion in the left temporal lobe, consistent with the patient's ictal EEG. 18-FDG PET shows reduced metabolism in the overlying cortex. All imaging data were concordant with electroclinical and neuropsychological data and the patient underwent a neocortical temporal lobectomy. The patient has since remained seizure-free. Histopathology after temporal lobectomy showed FCD type 2A.

Multimodal neuroimaging in presurgical evaluation of childhood epilepsy

Korean J Pediatr. 2010 August;53(8):779-785.
Fig. 2

Outcome of matching two one-dimensional signals with similar shapes. (A) The signal shapes differ in a small region resembling a site of hyperperfusion on ictal SPECT study and hypoperfusion on interictal study. The results of signal matching are shown using three techniques: mean ratio (B), l₂ norm (C) and l₁ norm (D).

QUANTITATIVE MULTI-COMPARTMENTAL SPECT IMAGE ANALYSIS FOR LATERALIZATION OF TEMPORAL LOBE EPILEPSY

Epilepsy Res. 2011 June;95(1-2):35-50.

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Contralateral hyperperfusion and ipsilateral hypoperfusion by ictal SPECT in patients with mesial temporal lobe epilepsy. [Epilepsy Res. 2010]
Contralateral hyperperfusion and ipsilateral hypoperfusion by ictal SPECT in patients with mesial temporal lobe epilepsy.
Cho JW, Hong SB, Lee JH, Kang JW, Lee MJ, Lee JY, Park HS, Suh M, Joo EY, Seo DW. Epilepsy Res. 2010 Feb; 88(2-3):247-54. Epub 2010 Jan 25.
Ictal hyperperfusion of cerebellum and basal ganglia in temporal lobe epilepsy: SPECT subtraction with MRI coregistration. [J Nucl Med. 2001]
Ictal hyperperfusion of cerebellum and basal ganglia in temporal lobe epilepsy: SPECT subtraction with MRI coregistration.
Shin WC, Hong SB, Tae WS, Seo DW, Kim SE. J Nucl Med. 2001 Jun; 42(6):853-8.
Arterial spin-labeling demonstrates ictal cortical hyperperfusion in epilepsy secondary to hemimegalencephaly. [J Neuroradiol. 2009]
Arterial spin-labeling demonstrates ictal cortical hyperperfusion in epilepsy secondary to hemimegalencephaly.
Altrichter S, Pendse N, Wissmeyer M, Jägersberg M, Federspiel A, Viallon M, Seeck M, Lövblad KO. J Neuroradiol. 2009 Dec; 36(5):303-5. Epub 2009 May 31.

10 free full-text articles in PubMed Central

Stimulus-induced, sleep-bound, focal seizures: a case report. [Sleep. 2011]
Stimulus-induced, sleep-bound, focal seizures: a case report.
Siclari F, Nobili L, Lo Russo G, Moscato A, Buck A, Bassetti CL, Khatami R. Sleep. 2011 Dec 1; 34(12):1727-30. Epub 2011 Dec 1.
Blood-brain barrier breakdown as a novel mechanism underlying cerebral hyperperfusion syndrome. [J Neurol. 2010]
Blood-brain barrier breakdown as a novel mechanism underlying cerebral hyperperfusion syndrome.
Ivens S, Gabriel S, Greenberg G, Friedman A, Shelef I. J Neurol. 2010 Apr; 257(4):615-20. Epub 2009 Nov 22.
Ictal SPECT statistical parametric mapping in temporal lobe epilepsy surgery. [Neurology. 2010]
Ictal SPECT statistical parametric mapping in temporal lobe epilepsy surgery.
Kazemi NJ, Worrell GA, Stead SM, Brinkmann BH, Mullan BP, O'Brien TJ, So EL. Neurology. 2010 Jan 5; 74(1):70-6.